- Inflammatory Bowel Disease
- Microscopic Colitis
- Orthopaedic implants and arthroplasty
- Hip disorders and treatments
- Orthopedic Surgery and Rehabilitation
- Total Knee Arthroplasty Outcomes
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Gastrointestinal Bleeding Diagnosis and Treatment
- Foot and Ankle Surgery
- Autoimmune and Inflammatory Disorders
- Eosinophilic Esophagitis
- Sports injuries and prevention
- Colorectal Cancer Screening and Detection
- Bone fractures and treatments
- Hip and Femur Fractures
- Knee injuries and reconstruction techniques
- Pancreatic and Hepatic Oncology Research
- Shoulder Injury and Treatment
- Gallbladder and Bile Duct Disorders
- Tendon Structure and Treatment
- Immunodeficiency and Autoimmune Disorders
- Diverticular Disease and Complications
- Head and Neck Surgical Oncology
- Orthopedic Infections and Treatments
Université de Lille
2013-2025
Hôpital Claude Huriez
2013-2025
Centre Hospitalier Universitaire de Lille
2013-2025
Institut de France
2025
Centre Hospitalier Régional Universitaire de Brest
2007-2023
Hôpital Saint-Antoine
2023
Sorbonne Université
2018-2023
Assistance Publique – Hôpitaux de Paris
2018-2023
Laboratoire de Traitement de l'Information Médicale
2006-2023
Inserm
2006-2020
Objectives The aim of this study was to compare endoscopic ultrasound‐guided choledochoduodenostomy (EUS‐CDS) vs. EUS‐gallbladder drainage (EUS‐GBD) in cases failed retrograde cholangiopancreatography (ERCP) for jaundice resulting from malignant distal biliary obstruction (MDBO). Methods This multicenter retrospective included patients with obstructive secondary MDBO who underwent EUS‐GBD or EUS‐CDS lumen‐apposing metal stents after ERCP. primary end‐point clinical success rate. Secondary...
Abstract Background and study aims Capsule endoscopy (CE) is the preferred method for small bowel (SB) exploration. With a mean number of 50,000 SB frames per video, SBCE reading time-consuming tedious (30 to 60 minutes video). We describe large, multicenter database named CAD-CAP (Computer-Assisted Diagnosis CAPsule Endoscopy, CAD-CAP). This serve development CAD tools CE reading. Materials methods Twelve French centers were involved. All available third-generation SB-CE videos (Pillcam,...
Cementless primary total hip arthroplasty (THA) is associated with risks of bleeding and thromboembolism. Anticoagulants are effective as venous thromboprophylaxis, but an increased risk bleeding. Tranexamic acid (TXA) efficient antifibrinolytic agent, the mode timing its administration remain controversial. This study aimed to determine whether two intravenous (IV) TXA regimens (a three-hour two-dose (short-TXA) 11-hour four-dose (long-TXA)) were more than placebo in reducing perioperative...
ABSTRACT Background The number of studies exploring esophageal motility disorders using high‐resolution manometry (HRM) in patients with diverticula (ED) is limited. goal this study was to describe HRM ED and assess the added value provocative testing these patients. Methods Patients who underwent between 2010 2022 were retrospectively included. findings compared based on single water swallows (SWS), solid food upright seated position, both ManoView Medical Measurement Systems software. We...
Summary Background The notion of Crohn's disease (CD) as a chronic, progressive and disabling condition has led to the development new indexes: Lémann Index measuring cumulative bowel damage Inflammatory Bowel Disease (IBD) Disability Index, assessing functional disability. Aims To measure IBD in large prospective cohort CD patients assess correlation between these two indexes. Methods We performed study tertiary referral centre including all consecutive outpatients. assessed questionnaire...
Background and study aims We aimed to identify risk factors salvage technique for technical failures of endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) evaluate the short long-term consequences in patients with biliary obstruction. Patients methods This retrospective multicenter included EUS-CDS from 2018 2024. Cases were defined as failure classified follow: type1 (digestive-flange mispositioned), type2 (biliary-flange type3 (stent deployment failure), type4 (catheter-LAMS...
Monitoring muscle atrophy in patients undergoing anterolateral cruciate ligament reconstruction is pivotal for optimizing postoperative recovery. Conventionally, the uninjured contralateral limb serves as control. However, its relevance with prolonged physical activity hiatus due to knee instability remains uncertain. Our objectives were compare limbs within a control group by assessing combined force measurements, cross-sectional areas (CSAs), and neuromuscular activation. In addition, we...
Background: Prospective data about the acceptance and outcomes of switching from adalimumab (ADA) reference product (RP) to multiple ADA biosimilars in inflammatory bowel disease (IBD) patients are lacking. Objectives: To evaluate rate RP biosimilars, identify factors associated with non-acceptance, assess persistence at 6 12 months, determine reasons for discontinuation, analyze changes activity, explore patient perceptions months. Design: A prospective study was conducted a French tertiary...
Abstract Background and aims New techniques for endoscopic resection, including submucosal dissection (ESD), have been developed to allow en-bloc resection with very low recurrence rates organ sparing in patients without inflammatory bowel disease (IBD). Data on ESD the management of colorectal dysplasia IBD are scarce. We aimed evaluate efficacy safety treatment IBD. Methods conducted a retrospective multicenter cohort study that evaluated consecutive procedures visible from 20 French...
Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown etiology. The treatment UC challenging, especially when it associated with primary sclerosing cholangitis (PSC), the bile ducts that affects around 5% patients UC, and leads to an increased risk cholangiocarcinoma colorectal cancer. Microbiota considered play important role in pathogenesis although efficacy antibiotics this context only limited transient. Several studies have investigated use for PSC adult pediatric...
Abstract Introduction and study aims Accurate real-time endoscopic characterization of colorectal polyps is key to choosing the most appropriate treatment. Mastering currently available classifications challenging. We used validated criteria for these create a single table, named CONECCT, evaluated impact teaching program based on this tool. Methods A prospective multicenter involving GI fellows attending physicians was conducted. During first session, each trainee completed pretest...
When initial resection of rectal neuroendocrine tumors (r-NETs) is not R0, persistence local residue could lead to disease recurrence. This study aimed evaluate the interest systematic non-R0 r-NET scars.
Infliximab (IFX) is effective in inducing and maintaining remission patients with luminal anoperineal Crohn's disease (CD). However, treatment failure within 12 months after initiating IFX observed a significant proportion of patients. The aim the present study was to determine whether body mass index (BMI) affects response during first year CD. All CD who began between January 2010 May 2014 were prospectively included. BMI calculated before begun, divided into 3 groups: normal (BMI < 25...
Abstract Background Although ulcerative proctitis [UP] can dramatically impair quality of life, treatment efficacy has been poorly investigated in UP as it was historically excluded from phase 2/3 randomised controlled trials colitis. Our aim to assess the effectiveness and safety tofacitinib for UP. Methods We conducted a retrospective, multicentre study 17 GETAID centres, including consecutive patients with treated tofacitinib. The primary endpoint steroid-free remission between Week 8 14,...
Abstract Background Standard high-volume polyethylene glycol [PEG] bowel preparations [PEG-4L] are recommended for patients with inflammatory disease [IBD] undergoing colonoscopy. However, low-volume [≤2 L of active volume] often used in clinical practice. The aim this study was to evaluate the efficacy, tolerability, and safety various IBD, including preparations. Methods We conducted a French prospective multicentre observational over period 1 month. Patients aged 18–75 years IBD an...