A5072224155- Organ Transplantation Techniques and Outcomes
- Clinical Nutrition and Gastroenterology
- Renal Transplantation Outcomes and Treatments
- Liver Disease and Transplantation
- Organ and Tissue Transplantation Research
- Pancreatic function and diabetes
- Hematopoietic Stem Cell Transplantation
- Transplantation: Methods and Outcomes
- Liver Disease Diagnosis and Treatment
- Organ Donation and Transplantation
- Immune Cell Function and Interaction
- Cytomegalovirus and herpesvirus research
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital Anomalies and Fetal Surgery
- Hepatitis C virus research
- Reconstructive Surgery and Microvascular Techniques
- Diabetes and associated disorders
- Metabolism and Genetic Disorders
- Nutrition and Health in Aging
- Intestinal Malrotation and Obstruction Disorders
- Liver Diseases and Immunity
- RNA Interference and Gene Delivery
- Diabetes Treatment and Management
- Enhanced Recovery After Surgery
- Viral-associated cancers and disorders
Miami Transplant Institute
2015-2025
Jackson Health System
2021-2025
University of Miami
2014-2024
Jackson Memorial Hospital
2006-2023
Hellenic Agency for Local Development and Local Government
2021
National and Kapodistrian University of Athens
2021
University of Rome Tor Vergata
2021
Sahlgrenska University Hospital
2021
University of Gothenburg
2021
Broward Health
2014
Background: The ideal goals in penile reconstruction are well described, but the multitude of flaps used for phalloplasty only demonstrates that none these techniques is considered ideal. Still, radial forearm flap most frequently and universally as standard technique. Methods: In this article, authors describe largest series to date 287 phalloplasties performed by same surgical team. Many different outcome parameters have been described separately previously published articles, main purpose...
In Brief Objective: The objective of this study was to summarize the evolution multivisceral transplantation over a decade experience and evaluate its current status. Summary Background Data: Multivisceral can be valuable for treatment patients with massive abdominal catastrophes. Its major limitations have been technical rejection intestinal graft. Methods: This consisted an outcome analysis 98 consecutive who received at our institution. represents largest single center date. Results: most...
Tactile and erogenous sensitivity in reconstructed genitals is one of the goals sex reassignment surgery. Since November 1993 until April 2003, a total 105 phalloplasties with radial forearm free flap 127 vaginoclitoridoplasties inverted penoscrotal skin dorsal glans pedicled have been performed at Ghent University Hospital. The specific surgical tricks used to preserve genital tactile are presented. In phalloplasty, hood clitoris incorporated into neoscrotum; transposed, buried, fixed...
To identify complications associated with different techniques utilized to treat portal vein thrombosis (PVT) during primary liver transplantation and their impact on survival.PVT remains an intricate problem in transplantation, the long-term outcomes of patients PVT who undergo are not well defined.We performed a retrospective cohort analysis all consecutive adult underwent isolated from 1998 2009 (median follow-up period, 89 months). The were compared those without PVT.Among 1379...
Mortality on the liver waitlist remains unacceptably high. Donation after circulatory determination of death (DCD) donors are considered marginal but a potentially underutilized resource. Thoraco-abdominal normothermic perfusion (TA-NRP) in DCD might result higher quality livers and offset mortality. We retrospectively reviewed outcomes first 13 transplanted from TA-NRP US. Nine centers eight organ procurement organizations. Median donor age was 25 years; median agonal phase minutes....
In Brief Objective: To describe a single-center experience of pediatric intestinal transplantation (Itx) and to provide an overview the children who underwent this procedure along with their outcomes. Summary Background Data: Pediatric Itx presents multiple challenges because very young ages at which patients require higher susceptibility infectious complications. Methods: We have performed 141 in 123 median age 1.37 years. Primary grafts included isolated intestine (n = 28), liver 27),...
Background. The development of strategies to enhance survival transplanted organs and potentially lower or even discontinue immunosuppressive therapy would represent a significant advance in posttransplant patient care. aim this clinical trial was determine the effect timing dose peripheral donor bone marrow cell (DBMC) infusion on graft after liver transplantation. Methods. DBMC, obtained from vertebral bodies, were administered 101 recipients allografts (OLTX). There 107 patients for whom...
We investigated the role of donor bone marrow cell (DBMC) infusions in immunosuppression withdrawal adult liver transplantation. Patients enrolled were at least 3 years post-transplantation, with stable graft function. Forty-five (study group: G1) received DBMC, and 59 (control G2) did not. Immunosuppression was reduced by one third upon enrollment, another second year study completely withdrawn year. Patient survival similar between two groups. Although rejection episodes significantly less...
Background. Graft-versus-host-disease (GVHD) is a rare complication but carries high mortality after transplantation. We retrospectively evaluated the incidence, risk factors and impact of this on survival outcome intestinal transplantation at single center. Methods. 241 patients who underwent between March 1994 July 2007 were analyzed for evidence GVHD. A diagnosis GVHD was based clinical presentations confirmed by histological findings. Results. Of patients, 22 (9.1%) diagnosed as The...
Introduction. Abdominal wall closure management has become an important challenge during recipient candidate selection, at the time of donor to matching and planning surgical procedure for intestinal or multiorgan transplantation. Different strategies have been proposed overcome lack abdominal domain: reduce graft size increase domain. Based on recent concept using acellular dermis matrix (Alloderm) availability tissues from same organ donor, we conceived idea fascia rectus muscle (FoRM) as...
Progressive graft dysfunction (GDF) and loss of insulin independence (II) have been invariably observed in islet transplant recipients under the "Edmonton protocol." To reestablish II, we performed supplemental infusions (SI) allogeneic alone, displaying GDF. improve engraftment long-term function SI, exenatide (EXN) etanercept treatment at infusion, EXN were tested a non-randomized pilot clinical trial.
Selvaggi, Gennaro M.D.; Monstrey, Stan M.D., Ph.D.; Hoebeke, Piet Ceulemans, Peter Van Landuyt, Koen Hamdi, Moustapha Cameron, Bowman Blondeel, Phillip Ph.D. Author Information
Porto-caval hemitransposition (PCH) in liver transplantation allows revascularization of the when porto-mesenteric axis is thrombosed. We, here, review our experience over an 11-year period. A total 23 patients underwent using PCH. Immunosuppression was based on tacrolimus, with sirolimus used case renal insufficiency. Most common diagnoses were hepatitis C, Laennec's, Budd-Chiari and cryptogenic cirrhosis. Six needed splenectomy prior to transplant, 5 during 1 post-transplant, 11 had no...
Background. A current limitation of islet transplantation is reduced long-term graft function. The glucagon-like peptide-1 receptor agonist, exenatide (Byetta, Amylin Pharmaceuticals, CA) has properties that could improve existing function, prevent further loss mass and possibly even stimulate regeneration. Methods. This prospective study evaluated the safety, efficacy, metabolic effects in subjects with type 1 diabetes mellitus allograft dysfunction requiring exogenous insulin. Results....
Evaluation of the clinical impact including donor colon and ileocecal valve in patients receiving primary intestinal transplantation has not been performed a sufficiently large series cases.Cox stepwise regression overall cause-specific graft survival was to evaluate our single center cohort 245 consecutive transplant recipients, among which 93 received colon.Inclusion had no significant on either univariable (P=0.13) or multivariable (P=0.45) analysis, nor hazard rates death caused by...
Background. The beneficial effects of glycemic control on both survival and function transplanted kidneys in patients with type 1 diabetes mellitus (T1DM) end-stage renal disease (ESRD) have been recognized. Methods. Herein, we present the clinical outcome a single-center pilot trial islet after kidney (IAK) transplantation seven T1DM. immunosuppression protocol for graft was converted to sirolimus+tacrolimus regimen 6 months before exclude negative function. Primary endpoint achievement...
Background. Donor-specific antibodies (DSA) are associated with acute kidney graft rejection, but their role in small bowel/multivisceral allograft remains unclear. We carried out a prospective study to understand the impact of DSA setting intestinal rejection. Methods. Thirteen patients (15 grafts) were serially evaluated for levels pre- and posttransplant. was determined by Luminex results interpreted as fluorescence intensity (FI), FI more than 3000 considered positive. Results. The...
Protocol Doppler ultrasonography of the liver (DUSL) is useful for detecting early hepatic artery thrombosis (HAT). Urgent exploration based on DUSL findings and immediate revascularization may avoid HAT-related sequelae, namely, biliary complications retransplantation after pediatric transplantation.Case-control study.University hospital.Group 1 included 96 transplantations performed in 75 patients from June 1, 1994, to August 31, 1999. Group 2 43 39 September 1999, 30, 2001.In group was...
Due to the known high recurrence rate of hepatitis C virus (HCV) among orthotopic liver transplant (OLT) recipients who receive tacrolimus+corticosteroid maintenance, use steroid-free induction was considered.OLT with HCV were randomized tacrolimus+daclizumab (steroid-free) vs. tacrolimus+corticosteroids during 1999-2001 and then tacrolimus+mycophenolate mofetil (MMF)+daclizumab tacrolimus+MMF+corticosteroids 2002-2005. Patients in arm both periods received no steroids except for treating...
Background. The immune monitoring of islet transplant recipients includes the assessment panel reactive antibodies (PRA). A negative association PRA+ with allogeneic solid organ graft survival has been recognized, but scattered data is available for transplantation. Methods. We performed a retrospective analysis PRA status in 66 patients type 1 diabetes mellitus recipient allografts between 1985 and 2006. Results. Pretransplant was observed 10 subjects old trials associated kidney...