A5059332651- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Radiomics and Machine Learning in Medical Imaging
- Amino Acid Enzymes and Metabolism
- Alzheimer's disease research and treatments
- Dementia and Cognitive Impairment Research
- Advanced MRI Techniques and Applications
- Prostate Cancer Treatment and Research
- Glioma Diagnosis and Treatment
- Epigenetics and DNA Methylation
- Cancer, Hypoxia, and Metabolism
- Prostate Cancer Diagnosis and Treatment
- Metabolism and Genetic Disorders
- Functional Brain Connectivity Studies
- Neuroscience and Neuropharmacology Research
- MRI in cancer diagnosis
- Neurotransmitter Receptor Influence on Behavior
- Neuroblastoma Research and Treatments
- Cardiac Imaging and Diagnostics
- Treatment of Major Depression
- Radiation Dose and Imaging
- Lanthanide and Transition Metal Complexes
- Advanced Neuroimaging Techniques and Applications
- Medical Imaging and Pathology Studies
- S100 Proteins and Annexins
University of Alabama at Birmingham
2016-2025
Emory University
2001-2025
National Institutes of Health
2025
Johns Hopkins University
2025
Duke University
2023
University of Pennsylvania
2023
O'Neal Comprehensive Cancer Center
2020-2022
University of Colorado Denver
2020-2022
University of Colorado Cancer Center
2020-2022
University of Alabama
2022
These joint practice guidelines, or procedure standards, were developed collaboratively by the European Association of Nuclear Medicine (EANM), Society and Molecular Imaging (SNMMI), Neurooncology (EANO), working group for Response Assessment in with PET (PET-RANO). Brain imaging is being increasingly used to supplement MRI clinical management glioma. The aim these standards/guidelines assist nuclear medicine practitioners recommending, performing, interpreting reporting results brain...
<h3>Importance</h3> In vivo tau imaging may become a diagnostic marker for Alzheimer disease (AD) and provides insights into the pathophysiology of AD. <h3>Objective</h3> To evaluate usefulness [<sup>18</sup>F]-AV-1451 positron emission tomography (PET) to stage AD assess associations among β-amyloid (Aβ), tau, volume loss. <h3>Design, Setting, Participants</h3> An study conducted at Knight Disease Research Center Washington University in St Louis, Missouri. A total 59 participants who were...
The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an international scientific professional organization founded in 1954 to promote the science, technology, practical application nuclear medicine. Its 18,000 members are physicians, technologists, scientists specializing
The importance of stereochemistry in drug action is gaining greater attention medical practice, and a basic knowledge the subject will be necessary for clinicians to make informed decisions regarding use single-enantiomer drugs. Many drugs currently used psychiatric practice are mixtures enantiomers. For some therapeutics, formulations can provide selectivities their biological targets, improved therapeutic indices, and/or better pharmacokinetics than mixture This article reviews...
The two primary molecular pathologies in Alzheimer's disease are amyloid-β plaques and tau-immunoreactive neurofibrillary tangles. Investigations into these have been restricted to cerebrospinal fluid assays, positron emission tomography tracers that can image plaques. Tau recently introduced the field, although utility of tracer its relationship other Alzheimer biomarkers still unknown. Here we examined tau deposition 41 cognitively normal 11 impaired older adults using radioactive ligand...
The NCCN Clinical Practice Guidelines in Oncology for Hodgkin Lymphoma (HL) provide recommendations the management of adult patients with HL. panel meets at least annually to review comments from reviewers within their institutions, examine relevant data, and reevaluate update recommendations. Current classic HL involves initial treatment chemotherapy alone or combined modality therapy followed by restaging PET/CT assess response. Overall, introduction less toxic more effective regimens has...
Haploinsufficiency of the SLC2A1 gene and paucity its translated product, glucose transporter-1 (Glut1) protein, disrupt brain function cause neurodevelopmental disorder, Glut1 deficiency syndrome (Glut1 DS). There is little to suggest how reduced causes cognitive dysfunction no optimal treatment for DS. We used model mice demonstrate that low protein arrests cerebral angiogenesis, resulting in a profound diminution microvasculature without compromising blood-brain barrier. Studies define...
Hodgkin lymphoma (HL) is an uncommon malignancy of B-cell origin. Classical HL (cHL) and nodular lymphocyte–predominant are the 2 main types HL. The cure rates for have increased so markedly with advent modern treatment options that overriding considerations often relate to long-term toxicity. These NCCN Guidelines Insights discuss recent updates focusing on (1) radiation therapy dose constraints in management patients HL, (2) advanced-stage relapsed or refractory cHL.
To assess the presence of brain and systemic inflammation in subjects newly diagnosed with Parkinson's disease (PD).Evidence for a pathophysiologic role PD is growing. However, several key gaps remain as to PD, including extent immune activation at early stages, potential effects treatments on whether pro-inflammatory signals are associated clinical features and/or predict more rapid progression.We enrolled de novo (n = 58) age-matched controls 62). Subjects underwent assessments, Movement...
Abstract The Dominantly Inherited Alzheimer Network (DIAN) is an international collaboration studying autosomal dominant disease (ADAD). ADAD arises from mutations occurring in three genes. Offspring families have a 50% chance of inheriting their familial mutation, so non-carrier siblings can be recruited for comparisons case–control studies. age onset highly predictable within families, allowing researchers to estimate individual’s point the trajectory. These characteristics allow candidate...
Abstract The American College of Radiology (ACR) and Nuclear Medicine (ACNM) collaborated to develop a clinical practice document for the performance fluciclovine positron-emission tomography (PET) / computed (CT) in evaluation patients with suspected prostate cancer recurrence based on elevation prostate-specific antigen (PSA) level (biochemical recurrence) after prior therapy. Prostate is third leading cause death United States. Up 50% diagnosed will biochemical failure initial...