Mengmeng Wen

ORCID: 0000-0003-4687-219X
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About
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Research Areas
  • Functional Brain Connectivity Studies
  • Neural dynamics and brain function
  • Mental Health Research Topics
  • Advanced MRI Techniques and Applications
  • Advanced Neuroimaging Techniques and Applications
  • Neurotransmitter Receptor Influence on Behavior
  • Schizophrenia research and treatment
  • Obstructive Sleep Apnea Research
  • Impact of Technology on Adolescents
  • Ferroptosis and cancer prognosis
  • Optical Imaging and Spectroscopy Techniques
  • Tracheal and airway disorders
  • Attention Deficit Hyperactivity Disorder
  • Motivation and Self-Concept in Sports
  • Online Learning and Analytics
  • Neuroscience of respiration and sleep
  • Glioma Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Innovative Teaching Methods
  • Heart Rate Variability and Autonomic Control

Zhengzhou Central Hospital
2022-2023

First Affiliated Hospital of Zhengzhou University
2020-2022

Peking University
2017

Abstract Background As a neuroprogressive illness, depression is accompanied by brain structural abnormality that extends to many regions. However, the progressive alteration pattern remains unknown. Methods To elaborate of according illness duration, we recruited 195 never-treated first-episode patients with and 130 healthy controls (HCs) undergoing T1-weighted MRI scans. Voxel-based morphometry method was adopted measure gray matter volume (GMV) for each participant. Patients were first...

10.1017/s0033291721003986 article EN Psychological Medicine 2021-09-29

Background: Patients with Internet gaming disorder (IGD) and attention-deficit/hyperactivity (ADHD) have high comorbidity but it is still unknown whether these disorders shared distinctive neuroimage alterations. Objective: The aim of this meta-analysis was to identify disorder-specific structural, functional, multimodal abnormalities between IGD ADHD. Methods: A systematic literature search conducted for whole-brain voxel-based morphometry (VBM) functional magnetic resonance imaging (fMRI)...

10.3389/fpsyt.2021.679437 article EN cc-by Frontiers in Psychiatry 2021-07-01

Background: Major depressive disorder (MDD) has demonstrated abnormalities of static intrinsic brain activity measured by amplitude low-frequency fluctuation (ALFF). Recent studies regarding the resting-state functional magnetic resonance imaging (rs-fMRI) have found is inherently dynamic over time. Little known, however, temporal dynamics local neural in MDD. Here, we investigated whether changes spontaneous are influenced Methods: We recruited 81 first-episode, drug-naive MDD patients and...

10.3389/fpsyt.2021.683610 article EN cc-by Frontiers in Psychiatry 2021-07-19

Abstract Smoking is companied with altered intrinsic activity of the brain measured by amplitude low‐frequency fluctuation. Evidence has revealed that human a highly dynamic and rapidly changing system. How exactly cigarette smoking affect temporal not fully understood nor it clear how severity influences spontaneous activity. Dynamic fluctuation (dALFF) was used to examine variability in 93 participants (63 smokers, 30 nonsmokers). We further divided smokers into light heavy smokers. The...

10.1111/adb.13050 article EN Addiction Biology 2021-06-03

Previous studies have implicated abnormal functional coordination in brain regions of smokers. Neuroimaging demonstrated alternations connectivity by using the resting-state (rsFC) method which arbitrarily chooses specific networks or seed as priori selections and cannot provide a full picture FC changes chronic The aim this study was to investigate whole-brain measured density (FCD). As variance activity, dynamic FCD (dFCD) performed integration In total, 120 smokers 56 nonsmokers were...

10.3389/fpsyt.2022.843254 article EN cc-by Frontiers in Psychiatry 2022-04-21

Early diagnosis is important for treatment and prognosis of obstructive sleep apnea (OSA)in children. Polysomnography (PSG) the gold standard OSA. However, due to various reasons, such as inconvenient implementation, less equipped in primary medical institutions, etc., it used children, especially young This study aims establish a new diagnostic method with imaging data upper airway clinical signs symptoms.In this retrospective study, were collected from children ≤10 years old who underwent...

10.3389/fmed.2023.1150321 article EN cc-by Frontiers in Medicine 2023-03-17

BACKGROUND:The tract-based spatial statistics (TBSS) method was used to investigate the changes of white matter microstructure in tobacco addicts, and analyze its correlation with smoking index, years, daily amount. MATERIAL AND METHODS:Routine magnetic resonance imaging (excluding intracranial lesions) diffusion tensor (DTI) sequence scanning were performed 156 nicotine addicts (nicotine dependence group) 81 non-nicotine (control recruited from study group. TBSS preprocess DTI data, age...

10.12659/msm.919105 article EN Medical Science Monitor 2020-01-03

Abstract Objective To study the value of whole-tumor histogram analysis which is based on apparent diffusion coefficient maps in grading diagnosis ependymoma. Methods 71 patients with ependymal tumors were retrospectively analyzed, including 13 cases WHO grade I, 28 II, and 30 III. Mazda software was used to draw region interest (ROI) three groups every layer tumor level. The gray carried obtained nine characteristic parameters, mean, variance, kurtosis, skewness, Perc.01%, Perc.10%,...

10.1007/s42058-019-00019-w article EN cc-by Chinese Journal of Academic Radiology 2020-01-09

Objective To understand the current situation of scientific exercise literacy middle school students, including basic knowledge, attitude, skills and habits. Methods One was selected from each Shulan county in Jilin province, Wuxi city Jiangsu province Chengdu Sichuan two junior high schools one senior school. Two classes were randomly grade three schools. All students took part study. 1 360 questionnaires distributed all collected, 355 them qualified questionnaires. The questionnaire...

10.3760/cma.j.issn.1674-0815.2017.05.006 article EN Chin J Health Manage 2017-10-20

Objective: To explore the alterations of cerebral cortical thickness in severe nicotine addicts by using surface-based morphology (SBM) method and further analyzing association these changes with smoking-related characteristics. Methods: Data were retrospectively collected from August 2014 to 2019 [aged 25 52(38±8)years] 56 non-smokers healthy volunteers 22 51(36±8)years]. All subjects underwent 3.0 T magnetic resonance scans, FreeSurfer software was used analyze difference between two...

10.3760/cma.j.cn112137-20220706-01499 article EN PubMed 2022-09-20
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