A5057357641- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Functional Brain Connectivity Studies
- Psychosomatic Disorders and Their Treatments
- Treatment of Major Depression
- Mental Health Research Topics
- Sleep and related disorders
- Electroconvulsive Therapy Studies
- Neural and Behavioral Psychology Studies
- Sleep and Wakefulness Research
- Mindfulness and Compassion Interventions
- Neuroscience and Music Perception
- Child and Adolescent Psychosocial and Emotional Development
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Tryptophan and brain disorders
- Attention Deficit Hyperactivity Disorder
- Perfectionism, Procrastination, Anxiety Studies
- Bipolar Disorder and Treatment
- Advanced Neuroimaging Techniques and Applications
- Obsessive-Compulsive Spectrum Disorders
- Neurotransmitter Receptor Influence on Behavior
- Smoking Behavior and Cessation
- Stress Responses and Cortisol
- Behavioral Health and Interventions
- Heart Rate Variability and Autonomic Control
University of Basel
2020-2025
University of Zurich
2012-2024
University of Cambridge
2013-2024
Universitäre Psychiatrische Kliniken Basel
2021-2024
University Hospital of Basel
2021-2024
Kermanshah University of Medical Sciences
2023
Psychiatry Baselland
2023
University Hospital of Zurich
2012-2022
Klinik und Poliklinik für Psychiatrie und Psychotherapie
2015-2022
Amt für Umwelt
2022
Mindfulness—an attentive non-judgmental focus on present experiences—is increasingly incorporated in psychotherapeutic treatments as a skill fostering emotion regulation. Neurobiological mechanisms of actively induced regulation are associated with prefrontally mediated down-regulation of, for instance, the amygdala. We were interested neurobiological correlates short mindfulness instruction during emotional arousal. Using functional magnetic resonance imaging, we investigated effects...
CYP46, the gene encoding cholesterol 24-hydroxylase, plays a key role in hydroxylation of and thereby mediates its removal from brain.To study association polymorphic sites on CYP46 with Alzheimer disease (AD) traits risk development AD.Alzheimer (beta-amyloid load, beta-amyloid peptides, hyperphosphorylated tau protein) were assessed brain tissues cerebrospinal fluid patients AD control subjects. Genetic associations studied 2 independent populations.Specialized centers for memory disorders...
Insomnia is a common problem in the general population. To treat insomnia, medication therapies and insomnia-related cognitive-behavioral interventions are often applied. The aim of present study was to investigate influence acceptance commitment therapy (ACT) on sleep quality, dysfunctional beliefs attitudes, experiential avoidance, problems individuals with compared control condition. A total 35 participants diagnosed insomnia (mean age: 41.46 years old; 62.9% females) were randomly...
Abstract Investigation of the brain's white matter fiber tracts in social anxiety disorder (SAD) may provide insight into underlying pathophysiology. Because models pathological posit altered frontolimbic interactions, uncinate fasciculus (UF) connecting (orbito‐) frontal and temporal areas including amygdala is particular interest. Microstructural alterations parts UF have been reported previously, whereas examination as discrete tract with regard to more large‐scale properties still...
Social anxiety disorder (SAD) is the second leading disorder. On functional neurobiological level, specific brain regions involved in processing of anxiety-laden stimuli and emotion regulation have been shown to be hyperactive hyper-responsive SAD such as amygdala, insula orbito- prefrontal cortex. level structure, prior studies on anatomical differences resulted mixed partially contradictory findings. Based previous models SAD, this study examined cortical thickness structural magnetic...
The symptoms of obsessive-compulsive disorder (OCD) have been postulated to result from impaired executive functioning and excessive habit formation at the expense goal-directed control objectively demonstrated using neuropsychological tests in such patients. This study tested whether there is functional hypoactivation as well dysconnectivity discrete frontostriatal pathways during planning patients with OCD their unaffected first-degree relatives. In total, 21 comorbidity-free OCD, 19...
Research conducted on individuals with depression reveals that major depressive disorders (MDDs) coincide diminished levels of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) in brain, as well modifications subunit composition primary receptors (GABAA receptors) responsible for mediating GABAergic inhibition. Furthermore, there is substantial evidence supporting significant role GABA regulating stress within which a pivotal vulnerability factor mood disorders. readily available...
Smart phone use has become a part of people's everyday life. However, when the lack using smart to establish and maintain electronic communication is related psychological distress, such behavior may be considered modern-age phobia, or nomophobia (no mobile phobia). The aims present study were investigate among sample young adults associations between scores for symptoms depression, anxiety, stress, insomnia, obsessive-compulsive disorders.A total 537 students (mean age: 25.52 years; 42.3%...
The higher prevalence of major depressive disorder (MDD) in females relative to males is well-established. Some authors have posited this difference arises divergent symptom profiles vs. males. However, empirical tests hypothesis yielded equivocal results. Here, we investigate sex differences MDD individual symptoms and networks a treatment-seeking sample.