A5087083320- Railway Engineering and Dynamics
- Mechanical stress and fatigue analysis
- Mechanical Engineering and Vibrations Research
- Traditional Chinese Medicine Analysis
- Engineering Applied Research
- Tea Polyphenols and Effects
- Fatigue and fracture mechanics
- Brake Systems and Friction Analysis
- Genomics, phytochemicals, and oxidative stress
- Bioactive Compounds and Antitumor Agents
- Metabolomics and Mass Spectrometry Studies
Tongji University
2021-2022
Beijing University of Chinese Medicine
2017-2018
Angelica sinensis root (ASR) extract was obtained to investigate its effects on colorectal carcinogenesis in different stages of an Azoxymethane/Dextran sodium sulphate (AOM/DSS) model. In this study, we showed that ASR administration the initial stage AOM/DSS model had cancer preventive with decreasing tumor incidence and a high-grade intraepithelial neoplasia incidence. With respect DNA damage, amounts 8-oxoguanine γ-H2AX were suppressed colon tissue. The balance apoptosis proliferation...
Under-chassis equipment for a high-speed railway vehicle contributes significantly to the vibration response characteristics of car body. To study influence pattern under-chassis parameters and position distributions on body, rigid-flexible coupling dynamics model is established. The impact suspension frequency mass apparatus body was analyzed. Subsequently, device placement investigated. Furthermore, found that from single point cannot represent performance entire when adjusting...
This study aimed to investigate the colorectal cancer preventive effect of combined administration phenolic acids and supercritical extracts from Angelica sinensis. The AOM/DSS model in mice was adopted. Phenolic were administrated orally initial stage at a dose 1 g·kg⁻¹ BW, which withtherectal with three doses (15, 30, 60 BW). PCNA, 8-oxoguaine, γ-H2AX, iNOS COX-2 tested by immunohistochemistry Western blot assays. results showed that A. sinensis suppressed tumor growth cell proliferation,...
Based on the actual parameters of capacitor energy storage cabinet top monorail train, built cabinet’s finite element model. Then, according to EN 12663-1, set calibration conditions and fatigue working conditions. Carried out simulation calculation under different conditions, respectively. The results static show that maximum equivalent stress each node model is smaller than allowable all Therefore, strength meets design requirements. Plotted Goodman limit diagrams base metal weld modified...