A5102942089- Mosquito-borne diseases and control
- Malaria Research and Control
- Viral Infections and Outbreaks Research
- Viral Infections and Vectors
- Influenza Virus Research Studies
- interferon and immune responses
- Infection Control and Ventilation
- Lipid Membrane Structure and Behavior
- SARS-CoV-2 detection and testing
- Disaster Response and Management
- Climate Change and Health Impacts
- Respiratory viral infections research
- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- COVID-19 and healthcare impacts
- Liver Diseases and Immunity
- Viral gastroenteritis research and epidemiology
- COVID-19 epidemiological studies
- Insect Pest Control Strategies
- Hepatitis Viruses Studies and Epidemiology
- Helminth infection and control
- Hepatitis B Virus Studies
- Zoonotic diseases and public health
- Building Energy and Comfort Optimization
- Mathematical and Theoretical Epidemiology and Ecology Models
United States Department of Homeland Security
2020-2021
Battelle
2020-2021
University of Virginia
2015-2020
The University of Queensland
2010-2016
Coronavirus disease 2019 (COVID-19) was first identified in China late and is caused by newly severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Previous studies had reported the stability of SARS-CoV-2 cell culture media deposited onto surfaces under a limited set environmental conditions. Here, we broadly investigated effects relative humidity, temperature, droplet size on simulated clinically relevant matrix dried nonporous surfaces. The results show that decayed more rapidly...
In the absence of a vaccine, preventing spread severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is primary means to reduce impact 2019 disease (COVID-19). Multiple studies have reported presence SARS-CoV-2 genetic material on surfaces suggesting that fomite transmission feasible. High temperature inactivation virus has been previously suggested, but not shown. present study, we investigated environmental stability in clinically relevant matrix dried onto stainless steel at high...
Indoor residual spray (IRS) of insecticides and insecticide-treated bednets (ITNs) are the two most important malaria vector control tools in tropical world. Application both same locations is being implemented for endemic epidemic Africa. The assumed to have synergistic benefits reducing transmission because they act at multiple stages cycle. However, this assumption has not been rigorously examined, empirically or theoretically. Using mathematical modelling, we obtained conditions which a...
Many enveloped viruses infect cells within endocytic compartments. The pH drop that accompanies endosomal maturation, often in conjunction with proteolysis, triggers viral proteins to insert into the membrane and drive fusion. Fusion dynamics have been studied by tracking living cells, which limits precision fusion can be synchronized controlled, reconstituting synthetic membranes, introduces nonphysiological curvature composition. To overcome these limitations, we report chemically...
Previous laboratory studies of Ebola virus aerosols have used a variety different sampling devices to collect viral material for analysis. However, vary in their ability aerosol particles and preserve the infectivity collected viruses. If not accounted for, this variability has potential bias study outcomes confound comparisons between which samplers are used. In present study, five laboratory-scale were assessed at low high relative humidities. Relative humidity did affect physical...
A variety of methods have been developed for quantification infectious Ebola virus in clinical or laboratory samples, but existing often require extensive operator involvement, manual assay scoring, the use custom reagents. In this study, we utilize a recently Ebola-specific reporter cell line that expresses ZsGreen response to infection, conjunction with semi-automated processing and techniques, develop an unbiased, high-throughput microtitration vitro. This was found equivalent sensitivity...