A5009959324- Tracheal and airway disorders
- Blood Coagulation and Thrombosis Mechanisms
- Neuroscience of respiration and sleep
- Ear Surgery and Otitis Media
- Prenatal Substance Exposure Effects
- HIV/AIDS Research and Interventions
- Airway Management and Intubation Techniques
- Obstructive Sleep Apnea Research
- Homelessness and Social Issues
- Child and Adolescent Psychosocial and Emotional Development
- Head and Neck Anomalies
- Vitamin K Research Studies
- Bacterial Genetics and Biotechnology
- Sepsis Diagnosis and Treatment
- Sinusitis and nasal conditions
- Esophageal and GI Pathology
- Microbial Natural Products and Biosynthesis
- Birth, Development, and Health
- Substance Abuse Treatment and Outcomes
- Early Childhood Education and Development
- Renin-Angiotensin System Studies
- TGF-β signaling in diseases
- HIV Research and Treatment
- Protease and Inhibitor Mechanisms
- Tumors and Oncological Cases
CSIRO Manufacturing
2021
Boston University
2009-2019
WellSpan York Hospital
2016-2019
James Cook University Hospital
2002-2018
Harvard University
2014
Doctors Hospital
2014
Boston Medical Center
2011-2012
Eli Lilly (United States)
1991-2008
Foundation for Applied Molecular Evolution
2008
Oregon Medical Research Center
2003-2006
<h3>Background</h3> Functional brain imaging studies in major depression have suggested abnormalities of areas, including the frontal cortex, cingulate gyrus, basal ganglia, and temporal cortex. We hypothesized that venlafaxine hydrochloride interpersonal psychotherapy (IPT) might each alter blood flow some or all these areas on sequential single photon emission computed tomography (SPECT) scans. <h3>Methods</h3> Twenty-eight men women aged 30 to 53 years with a<i>DSM-IV</i>major depressive...
To propose a staging system for patients with lymphatic malformations of the head and neck.Retrospective chart review.Fifty-six were treated from 1983 to 1993 at Children's Hospital Medical Center, Seattle, Wash. The charts reviewed anatomic location lesion, preoperative postoperative complications, number procedures control disease, long-term sequelae, persistence disease. Lesions characterized as being unilateral or bilateral suprahyoid and/or infrahyoid. five patient groups then compared...
A cDNA, cRKIN1, encoding a putative homologue of the yeast (Saccharomyces cerevisiae) SNF1-encoded protein-serine/threonine kinase, has been isolated from library prepared rye endosperm mRNA. Northern blot analysis demonstrated presence cRKIN1-related transcripts in developing endosperms but not shoots, and Southern showed small gene family. SNF1 plays central role carbon catabolite repression expression RKIN1 sequence snf1 mutants restored function. This suggests that protein control metabolism rye.
Craniofacial anomalies (CFA) predispose children to airway obstruction. A retrospective study was conducted describe intervention required manage patients with craniofacial syndromes and diseases involving the midface mandible (i.e., Pierre Robin, Apert, Treacher Collins, Saethre-Chotzen, CHARGE, Nager, Stickler, Goldenhar, Pfeiffer). The type of intervention, duration associated physical medical conditions were evaluated. One hundred nine had charts available for review met inclusion...
Retrospective recall-based measures administered to adults, like the Childhood Trauma Questionnaire (CTQ), are commonly used determine experiences of childhood trauma in home. However, CTQ has not been compared with prospective violence exposure, whether at home or community. We evaluated relationships between young adults' responses and their self-reports exposure adolescence. Participants were 127 (93% African American, 47% male) urban adults a longitudinal birth cohort study examining...
The relationship between drug use, school performance, and academic aspirations among 446 Anglo Hispanic youths, age nine to seventeen, is explored. Two groups of subjects–current substance users non-users–were interviewed. Subjects in each comparison group were similar age, ethnicity, gender. Overall results, consistent with prior research, indicate a significant current future educational aspirations, use. No difference was noted use on indicators general interest work or probability...
• Cystic hygromas usually present in infancy or early childhood as compressible masses that may rapidly and intermittently enlarge. While they arise any anatomic location, of the head neck are especially difficult to manage since enlargement cause serious sequela such airway obstruction, feeding difficulties, speech pathology. Complete extirpation these lesions is often impossible, recurrence rates accordingly high. We reviewed our 10-year experience treating cervicofacial cystic hygromas....
Abstract Functional endoscopic sinus surgery (FESS) is being advocated to treat children with chronic sinusitis. The surgeon performing FESS needs an intimate understanding of the anatomy adequately disease and avoid complications. One hundred thirty‐six patients who had were reviewed. Preoperative direct coronal computed tomography scans available for review in 114 patients. Several nasal paranasal anomalies uncovered during this evaluation. most common was hypoplasia maxillary sinuses. All...
Abstract Our experience with the diagnosis and surgical management of 37 patients congenital atresia or severe stenosis both posterior nasal choanae is presented. Twenty‐five were repaired transnasally 12 transpalatally. Soft stents fashioned from Silastic® tubing used for 6 to weeks postoperatively. In 64% transnasal operations 83% transpalatal operations, full patency was achieved without necessity dilatations. most remaining one lumen remained patent.
Previous research has been inconsistent in documenting a strong relationship between depression and HIV/AIDS, although recent meta-analysis of studies examining this issue indicates that rates are modestly higher for population. For the current study, conducted from 2001–2004, we sought to examine types depressive symptoms cohort patients receiving HIV care at two urban medical centers. These were participants an intervention study adherence mental health persons triply diagnosed with...
Abstract Peripheral Sleep Apnea syndrome has been associated with enlarged tonsils and adenoids as well other abnormalities which may cause upper airway obstruction in children. A multidisciplinary approach is used at the Disorder Center of Cincinnati General Hospital to evaluate role sleep apnea. Polysomnographic techniques combined cine studies document degree, site type obstruction. This presentation highlights entity obstructive apnea provides a rational clinical management these patients.
The anticonvulsant topiramate not only decreases ethanol consumption in alcohol dependence (AD) but also may produce several adverse events including cognitive impairment. Zonisamide is a structurally related that promising agent for the treatment of AD and have greater tolerability than topiramate. This study evaluated effects zonisamide (400 mg/d) on its neurotoxic subjects with AD. A double-blind placebo-controlled clinical trial was conducted using 2 comparator drugs, (300 levetiracetam...
The Effective Black Parenting Program (EBPP), a culturally adapted, cognitive-behavioral parenting skill training program, was field tested on two cohorts of inner-city African-American parents and their first– second-grade children. Pre-post changes parental acceptance-rejection, family relationships, child behavior problems social competencies were compared in quasi-experimental design totalling 109 treatment 64 control families over 1 year. Results from Cohort I indicated that the EBPP...
• Sixty-six patients with recurrent respiratory papillomatosis of juvenile onset were treated for six months interferon alfa-n1 (Wellferon) in a randomized crossover trial. Half received intramuscularly at dosage 5 megaunits per square meter daily 28 days and then thrice weekly five months, followed by observation. The other half observed treated. Operations performed every two to assess disease extent scale developed this purpose. score the during first observation period was stable. There...