A5066669807- Environmental Toxicology and Ecotoxicology
- Pharmaceutical and Antibiotic Environmental Impacts
- Heavy metals in environment
- Toxic Organic Pollutants Impact
- Pesticide and Herbicide Environmental Studies
- Aquatic Invertebrate Ecology and Behavior
- Water Quality and Pollution Assessment
- Environmental DNA in Biodiversity Studies
- Microplastics and Plastic Pollution
- Carbohydrate Chemistry and Synthesis
- Glycosylation and Glycoproteins Research
- Per- and polyfluoroalkyl substances research
- Freshwater macroinvertebrate diversity and ecology
- Aquatic Ecosystems and Phytoplankton Dynamics
- Effects and risks of endocrine disrupting chemicals
- Mine drainage and remediation techniques
- Chromium effects and bioremediation
- Mercury impact and mitigation studies
- Chemical Synthesis and Analysis
- Microbial Community Ecology and Physiology
- Soil and Water Nutrient Dynamics
- Analytical chemistry methods development
- Atmospheric chemistry and aerosols
- Parasite Biology and Host Interactions
- Historical and Environmental Studies
École Polytechnique Fédérale de Lausanne
2016-2025
Swiss Federal Institute of Aquatic Science and Technology
2015-2024
Agroscope
2020
Forel Klinik
2004-2018
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2013-2017
Communauté urbaine de Lyon
2014-2016
Stress Environnementaux et Biosurveillance des Milieux Aquatiques
2010-2016
University of Geneva
2004-2013
Sanofi (France)
1994-2010
Biologie des Organismes et Écosystèmes Aquatiques
2009
Abstract In this study, exposure and ecotoxicity data of six human pharmaceuticals (carbamazepine, clofibric acid, diclofenac, ofloxacin, propranolol, sulfamethoxazole) were collected, including our own experimental literature data. From collection, the two-tiered European draft guideline on environmental risk assessment was tested. Measured concentrations in effluents from France surface waters Germany compared to predicted (PECs) both countries. a similar manner, no-effect (PNECs) derived...
DNA barcoding and metabarcoding is increasingly used to effectively precisely assess monitor biodiversity in aquatic ecosystems. As these methods rely on data availability quality of barcode reference libraries, it important develop follow best practices ensure optimal traceability the metadata associated with barcodes for identification. Sufficient metadata, as well vouchers, corresponding each must be available reliable library curation and, thereby, provide trustworthy baselines...
Tire and road wear particles (TRWP) account for an important part of the polymer released into environment. There are scientific knowledge gaps as to potential bioaccessibility chemicals associated with TRWP aquatic organisms. This study investigated solubilization seven most widely used tire-associated organic four their degradation products from cryogenically milled tire tread (CMTT) fish digestive fluids using in vitro digestion model based on Oncorhynchus mykiss. Our results showed that...
Recent advances in molecular biomonitoring open new horizons for aquatic ecosystem assessment. Rapid and cost-effective methods based on organismal DNA or environmental (eDNA) now offer the opportunity to produce inventories of indicator taxa that can subsequently be used assess biodiversity ecological quality. However, integration these DNA-based into current monitoring practices is not straightforward, will require coordinated actions coming years at national international levels. To plan...
Starting from the structure of novel nonpeptide AT1 receptor antagonist DuP 753 (losartan), a new series potent antagonists was designed. In these compounds central imidazole nucleus replaced by dihydroimidazol-4-one structure. The most active had spirocyclopentane or spirocyclohexane ring in position 5. Like series, best substituents were linear butyl chain 1 and [2'-(tetrazol-5-yl)biphenylyl]methyl group 3. Antagonistic activity assessed ability to competitively inhibit [125I]AII binding...
Negative impacts of human activities on stream ecosystems include the reduction/modification connectivity between surface water and groundwater contamination these resources. Vertical hydrological exchanges principally occur through coarse sediments hyporheic zone (porous matrix) compartments have property to store pollutants. Such participate in self-purification infiltration polluted can lead groundwater. A complete environmental monitoring program should therefore assessment biological...
Abstract Municipal solid waste incinerator bottom ash (MSWIBA) was used as a test matrix for comparing the responses of different variables (solid phase vs leachate media) through toxicity tests and resulting endpoints. Toxicity solid‐phase MSWIBA evaluated with three terrestrial plants, namely oats ( Avena sativa L.), Chinese cabbage Brassica campestris L. cv. chinensis ), lettuce Lactuca L.). Assessment endpoints these plant were biomass fresh weight, germination rate, oxidant stress...
Environmental risk assessment associated with aquatic and terrestrial contamination is mostly based on predicted or measured environmental concentrations of a limited list chemicals in restricted number compartments. High resolution mass spectrometry (HRMS) can provide more comprehensive picture exposure to harmful chemicals, particularly through the retrospective analysis digitally stored HRMS data. Using this methodology, our study characterized various compartments including 154 surface...
Tire and road wear particles (TRWP) have been shown to represent a large part of anthropogenic released into the environment. Nevertheless, potential ecological risk TRWP in different environmental compartments their toxic impacts on terrestrial aquatic organisms remain largely underinvestigated. Several heavy metals compose TRWP, including Zn, which is used as catalyst during vulcanization process rubber. This study investigated solubilization from cryogenically milled tire tread (CMTT)...
Three 2-acetamido-2-deoxy-α-d-galactopyranose residues attached to Ser2, Thr3 Thr4 of the amino-terminal portion glycophorin AM are responsible for so-called TN blood group specificity. In a continuation earlier work, this report describes first chemical synthesis triglycosylated pentapeptide H2N-Ser1-Se*r2-Th*r3-Th*r4-Gly5-OH, in which (*) represents 2-acetamido-2-deoxy-α-d-galactopyranosyl residue. This compound constitutes G1-G5 sequence human AM, main erythrocyte membrane glycoprotein....
Abstract Purpose Basing decisions for the management of contaminated sediments on ecotoxicological data is still often met with skepticism by European stakeholders. These concerns are discussed as they pertain to bioassays show how may provide added value sustainable sediment in aquatic systems. Materials and methods Five “concerns” selected that raised The practice light knowledge gained recent decades compared chemical analysis data. Results discussion Common assumptions such a higher...