A5100456720- Catalytic C–H Functionalization Methods
- Sulfur-Based Synthesis Techniques
- Radical Photochemical Reactions
- Chemical Synthesis and Reactions
- Oxidative Organic Chemistry Reactions
- Synthesis and Biological Evaluation
- Synthesis and Catalytic Reactions
- Supercapacitor Materials and Fabrication
- Fluorine in Organic Chemistry
- Advanced battery technologies research
- Electrocatalysts for Energy Conversion
- Conducting polymers and applications
- Multicomponent Synthesis of Heterocycles
- Synthesis and biological activity
- Advanced biosensing and bioanalysis techniques
- Catalytic Cross-Coupling Reactions
- Catalytic Processes in Materials Science
- Metal-Organic Frameworks: Synthesis and Applications
- Catalytic Alkyne Reactions
- Ammonia Synthesis and Nitrogen Reduction
- Electrochemical Analysis and Applications
- Fuel Cells and Related Materials
- Nanomaterials for catalytic reactions
- biodegradable polymer synthesis and properties
- Synthesis and Reactivity of Heterocycles
Zhejiang University of Technology
2016-2025
Central South University
2018-2025
Xiangya Hospital Central South University
2025
State Key Laboratory of Powder Metallurgy
2021-2024
Minjiang University
2024
The University of Texas at Dallas
2023-2024
Changzhi University
2023-2024
Peking University Cancer Hospital
2024
Peking University
2024
Taiyuan University of Technology
2023-2024
Electrosynthesis of hydrogen peroxide (H
Reduction-responsive biodegradable micelles were developed from disulfide-linked dextran-b-poly(ε-caprolactone) diblock copolymer (Dex-SS-PCL) and applied for triggered release of doxorubicin (DOX) in vitro inside cells. Dex-SS-PCL was readily synthesized by thiol-disulfide exchange reaction between dextran orthopyridyl disulfide (Dex-SS-py, 6000 Da) mercapto PCL (PCL-SH, 3100 Da). Dynamic light scattering (DLS) measurements showed that yielded with an average size about 60 nm a low...
Heteroatom-doping in metal-nitrogen-carbon single-atom catalysts (SACs) is considered a powerful strategy to promote the electrocatalytic CO2 reduction reaction (CO2 RR), but origin of enhanced catalytic activity still elusive. Here, we disclose that sulfur doping induces an obvious proton-feeding effect for RR. The model SAC catalyst with second-shell FeN4 (Fe1 -NSC) was verified by X-ray absorption spectroscopy and aberration-corrected scanning transmission electron microscopy. Fe1 -NSC...
Sulfonyl radicals generated from sulfonylhydrazides by the Bu4NI–tert-butyl hydroperoxide (TBHP) catalysis system underwent addition to a variety of α-methyl styrene derivatives give corresponding allylic sulfones. This selective sulfonylation is metal-free, operationally simple, and environmentally friendly.
A catalytic system consisting of KI, 18-crown-6, and TBHP for arylsulfonylation activated alkenes with sulfonylhydrazides as sulfonyl precursor is described. This protocol provides a practical environmentally benign method the construction sulfonated oxindoles in water.
Halosulfonylation of terminal alkynes was achieved with sulfonylhydrazides as the sulfonyl precursor and inexpensive iron halide source in presence TBHP, allowing regio- stereoselective generation (E)-β-chloro bromo vinylsulfones.
Circulating tumor cells (CTCs) are important indicators for diagnosis and metastasis. However, the extremely low levels of CTCs in peripheral blood challenges precise detection CTCs. Herein, we report DNA generated electrochemical current combined with rolling circle amplification (RCA) as well magnetic nanospheres highly efficient capture ultrasensitive The antiepithelial cell adhesion molecule (EpCAM) antibody-modified were used to enrich following binding an aptamer onto CTC surface...
A polycytosine DNA-based immunosensor for electrochemical detection was developed and tested of human epidermal growth factor receptor 2 (HER2), a breast cancer biomarker. We utilized gold nanoparticles (AuNPs) as supporting matrix to immobilize DNA sequence (dC20) current generation anti-HER2 antibodies. In the presence target HER2, sandwiched immunocomplex forms between peptide specific HER2 immobilized on electrode antibodies AuNPs. The captured by sensor is detected because reaction dC20...
A tetrabutylammonium iodide catalyzed method for the synthesis of allyl aryl sulfone derivatives with Baylis-Hillman acetates and sulfonylhydrazides using tert-butyl hydroperoxide as an oxidation agent in water has been developed. In this process, group eliminated from sulfonyl precursor is molecular nitrogen.
A novel arylalkoxycarbonylation of N-aryl acrylamides with carbazates leading to alkoxycarbonylated oxindoles has been developed. The reported reactions employ economical and environmentally benign FeCl2·4H2O as a catalyst easily accessible safe alkoxycarbonyl radical precursors.
Abstract Electrochemical production of hydrogen peroxide (H 2 O ) through two‐electron (2 e − oxygen reduction reaction (ORR) is an on‐site and clean route. Oxygen‐doped carbon materials with high ORR activity H selectivity have been considered as the promising catalysts, however, there still a lack direct experimental evidence to identify true active sites at complex surface. Herein, we propose chemical titration strategy decipher oxygen‐doped nanosheet (OCNS 900 catalyst for ORR. The OCNS...
Electrochemical CO2 reduction reaction (CO2 RR) is crucial to addressing environmental crises and producing chemicals. Proton activation transfer are essential in RR. To date, few research reviews have focused on this process its effect catalytic performance. Recent studies demonstrated ways improve RR by regulating proton dynamics. This Concept highlights the use of dynamics enhance for target product discusses modulation strategies operative mechanisms typical systems, including...
In oxygen reduction reaction to H
Abstract A practical and environmentally friendly strategy for generating alkoxycarbonyl radicals from readily available carbazates under metal‐free conditions has been developed. In the presence of tetrabutylammonium iodide tert ‐butyl hydroperoxide, 2‐isocyanobiphenyls smoothly underwent radical alkoxycarbonylation with to afford phenanthridine‐6‐carboxylates. magnified image
36 novel 1,5-benzodiazepine derivatives were synthesized and evaluated for their <italic>in vitro</italic> antimicrobial activity. The results revealed that most of the exhibited considerable potency against all tested strains.
A novel synthetic route toward pharmaceutically interesting β-keto-sulfone derivatives<italic>via</italic>TBAI/TBHP-mediated oxidative coupling of readily prepared enamides with sulfonylhydrazides is described.
Four porous interpenetrated fluorescent MOFs based on π-electron-rich N-donor ligands can effectively detect nitroaromatic explosives and exhibit highly sensitive responses to 2,4,6-trinitrophenol.
An efficient metal-free oxidative arylsulfonylation of α,β-unsaturated imides with sulfonylhydrazides leading to isoquinoline-1,3(2H,4H)-dione derivatives has been developed. The procedure involves the generation sulfonyl radicals via cleavage S-N bond sulfonylation and C-H functionalization. protocol uses economical environmentally friendly TBAI-TBHP catalytic system, corresponding isoquinoline-1,3(2H,4H)-diones various functional groups were obtained in moderate good yields.
A plausible mechanism for ring-opening polymerization of lactide catalyzed by Zn(C<sub>6</sub>F<sub>5</sub>)<sub>2</sub>-based Lewis pairs was proposed based on <italic>in situ</italic> NMR and MALDI-TOF MS analyses. Several experimental results show very good consistency with the mechanism.
The development of stable and effective catalysts to convert toxic H2S into high value-added sulfur is essential for production safety environmental protection. However, the inherent defects traditional iron- zirconium-based catalysts, such as poor activity, oxygen consumption, low selectivity, limit their further developments applications. Herein, Fe–Zr bimetallic organic framework FeUIO-66(x) with different cubic morphologies was synthesized via a facile solvothermal method. results...
The direct addition of in situ generated hydrazoic acid to alkynes is realized without solvent by using a gold catalyst derived from recently designed remotely functionalized biaryl-2-ylphosphine ligand (i.e., WangPhos). With terminal alkynes, the additions are mostly with 0.1 mol% loadings and at 40 °C. more challenging internal devoid EWG substitution, one-step transformation for first time generally high efficiency ambient temperature.