Nassim Safari

ORCID: 0000-0003-4742-6618
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About
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Research Areas
  • Plant Pathogens and Fungal Diseases
  • Mycotoxins in Agriculture and Food
  • Plant Disease Resistance and Genetics
  • Essential Oils and Antimicrobial Activity
  • Plant-Microbe Interactions and Immunity
  • Plant Stress Responses and Tolerance
  • Medicinal Plant Extracts Effects
  • Plant Virus Research Studies
  • Fungal and yeast genetics research
  • Redox biology and oxidative stress
  • Phytochemistry and Biological Activities
  • Insect and Pesticide Research
  • Wheat and Barley Genetics and Pathology
  • Mycorrhizal Fungi and Plant Interactions

Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau
2024

University of Kaiserslautern
2022-2024

University of Koblenz and Landau
2023

University of Zanjan
2020

Sapienza University of Rome
2020

Botrytis cinerea is a major plant pathogen infecting more than 1400 species. During invasion, the fungus rapidly kills host cells, which believed to be supported by induction of programmed cell death. To comprehensively evaluate contributions most currently known death inducing proteins (CDIPs) and metabolites for necrotrophic infection, an optimized CRISPR/Cas9 protocol was established allowed perform serial marker-free mutagenesis generate multiple deletion mutants lacking up 12 CDIPs....

10.1371/journal.ppat.1010367 article EN cc-by PLoS Pathogens 2022-03-03

Abstract Barley is a staple crop of major global importance and relatively resilient to wide range stress factors in the field. Transgenic reporter lines investigate physiological parameters during treatments remain scarce. We generated characterized transgenic homozygous barley (cv. Golden Promise Fast) expressing genetically encoded biosensor Grx1–roGFP2, which indicates redox potential antioxidant glutathione cytosol. Our results demonstrated functionality sensor living plants. determined...

10.1093/jxb/erae035 article EN Journal of Experimental Botany 2024-02-01

The devastating pathogen Botrytis cinerea infects a broad spectrum of host plants, causing great socio-economic losses. necrotrophic fungus rapidly kills plant cells, nourishing their wall and cellular contents. To this end, necrotrophs secrete cocktail cell degrading enzymes, phytotoxic proteins metabolites. Additionally, many fungi produce specialized invasion organs that generate high invasive pressures to force way into the cell. However, for most necrotrophs, including Botrytis,...

10.1111/nph.20025 article EN cc-by New Phytologist 2024-08-06

The use of plant extracts in pre- and post-harvest disease management agricultural crops to cope with aflatoxin B1 contamination has shown great promise due their capability managing toxins safe-keeping the quality. We investigated anti-aflatoxigenic effect multiple doses eight (Heracleum persicum, Peganum harmala, Crocus sativus, Trachyspermum ammi, Rosmarinus officinalis, Anethum graveolens, Berberis vulgaris, thunbergii) on Aspergillus flavus via LC-MS down-regulatory them aflR, aflM aflP...

10.3390/antibiotics9110728 article EN cc-by Antibiotics 2020-10-23

While Botrytis cinerea causes gray mold on many plants, its close relative, fabae, is host-specifically infecting predominantly faba bean plants. To explore the basis for narrow host range, a gapless genome sequence of B. fabae strain G12 (BfabG12) was generated. The BfabG12 encompasses 45.0 Mb, with 16 chromosomal telomere-to-telomere contigs that show high synteny and similarity to corresponding B05.10 (BcB0510) chromosomes. Compared BcB0510, it 6% larger, due AT-rich regions containing...

10.3390/jof10030216 article EN cc-by Journal of Fungi 2024-03-14

Melissa officinalis L. is used since ancient times in folk medicine because of its sedative, digestive, carminative, spasmolytic and analgesic effects. Its therapeutic impact due to the essential oil content rosmarinic acid. This study was designed determine chemical composition acid M. cultivated Fars province south Iran. The obtained by hydro-distillation dried aerial parts harvested analyzed gas chromatography-mass spectrometry (GC/MS). Rosmarinic determined high-performance liquid...

10.22092/jmpb.2020.123119 article EN Journal of Medicinal plants and By-product 2020-09-01

Abstract The devastating pathogen Botrytis cinerea infects a broad spectrum of host plants, causing great socio-economic losses. necrotrophic fungus rapidly kills plant cells, nourishing their walls and cellular contents. To this end, necrotrophs secretes cocktail cell wall degrading enzymes, phytotoxic proteins metabolites. Additionally, many fungi produce specialized invasion organs that generate high invasive pressures to force way into the cell. However, for most necrotrophs, including ,...

10.1101/2023.12.15.571920 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-12-16
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