Acute and persistent myocardial ischemia is the main cause of acute infarction (AMI) heart failure. MicroRNA-21(miR-21) contributes to pathophysiological consequences by targeting downstream crucial regulators. Thus, miR-21 mimics are a promising strategy for treatment AMI. However, their poor stability insufficient cellular uptake major challenges. Herein, we encapsulated into liposomes modified with cardiac troponin T (cTnT) antibody targeted delivery miR-21(cT-21-LIPs) ischemic...

Lanthanide metal possesses multiple oxide states, which endows it with potential advantages as promising catalysts for electrochemical ammonia synthesis. A universal method was developed to prepare Ln2O3@C (Ln = La, Er, Tb, and Eu) nanosheets via calcinating Ln-citrate under a N2 atmosphere. were obtained cation change method. The carbon from the carbonization of citrate not only supported generated lanthanide but also inhibited aggregation nanoparticles during high-temperature calcination....

As China’s economic development has shifted from quantitative growth to qualitative improvement, stakeholders have enforced stricter corporate social responsibility (CSR) requirements for listed companies. However, few studies focused on companies and CSR in such developing economies. We used the scoring system Hexun Finance’s website group Chinese according their scores. By comparing effects of merger acquisition (M&A) announcements different scores, we found that, first, average...

Purpose Based on resource dependence theory and transaction cost economics this study explores how green customer integration (GCI) affects financial performance via information sharing opportunistic behavior, the moderating effects of trust. Design/methodology/approach This develops a theoretical model tests it using data from two-waved survey 206 Chinese manufacturers. The hypotheses were tested hierarchical linear regression analysis. Findings results show that GCI has significant...

In a complex environment, how to construct resilient supply chain network (SCN) that can resist disruptions is problem of great concern in management. order provide some insights for constructing SCN, this paper studies the influence structures on SCN resilience from perspective networks. Considering exit and reselection enterprises have been ignored previous studies, we propose new model which nodes are connected with each other based degree, fitness distance. Subsequently, different...

The aim of this study is to investigate the impact network characteristics on supply chain resilience (SCNR) when risk propagation occurs in networks (SCNs). we here (e.g., clustering coefficient, scalar index, node type, etc.) are exceptionally important for real-life SCNs, but not sufficiently considered previous research SCNR. To end, first construct an SCN model with adjustable parameters multiple characteristics. Second, combined a susceptible–infectious–susceptible model. Third,...

We used the corporate social responsibility (CSR) data from Hexun Finance to analyze three channels of market investor evaluation in process Chinese listed companies’ mergers and acquisitions (M&A). found that: (1) because many CSR behaviors companies are passive, driven by environment, government, regulatory authority, rather than proactive for long-term interests company, investors not concerned with performance acquirers before merger; (2) passive behavior cannot change system risk...

The participation of Communist Party China （thereafter CPC） in corporate governance is an important feature structure China. CPC organizations play a political core or leading role both state-owned and non-state-owned companies. institution “two-way entry cross-appointment” combines with mechanisms such as the board directors supervisors organically enables to significant roles companies’ major production operation activities. Tax avoidance not only means that more wealth can be left...

Domain-specific term extraction contributes to all domain-oriented natural language processing tasks. Given a small set of domain-specific terms as seed terms, new from unlabeled corpora can be extracted by bootstrapping classifier discover the association between and terms. Traditional representation method for represents in feature space documents, which depicts share common documents. This can't depict inner-document information requires occur multiple A global contextual is proposed this...

We propose a tractable model of entrepreneur dynamics where the investment conditions are stochastic. Applying approach stochastic control and optimization, we solve entrepreneur’s optimal investment, consumption portfolio allocation under regime switching. find that interactions precautionary savings liquidation boundary advance/postpone motives generate rich implications for dynamics. Facing threat financial crisis, entrepreneurs build cash reserves bring forward option exercise to...

Discovering the relationship between protein sequence pattern and secondary structure is important for accurately predicting of sequence. A dictionary constructed using its corresponding in this paper. Based on dictionary, we propose four effect factors pattern, including 1) core itself; 2) patterns or amino acid residues that neighbor with pattern; 3) are far away from 4) segment match pattern. Statistical measures adopted to analyze these factors. The experimental result shows reliability...