- Light effects on plants
- Photosynthetic Processes and Mechanisms
- Advanced biosensing and bioanalysis techniques
- Environmental and Agricultural Sciences
- Plant Stress Responses and Tolerance
- Crop Yield and Soil Fertility
- Plant Molecular Biology Research
- Wheat and Barley Genetics and Pathology
- MicroRNA in disease regulation
- RNA Interference and Gene Delivery
- Polysaccharides and Plant Cell Walls
- Animal Nutrition and Physiology
- Gene expression and cancer classification
- Cancer-related molecular mechanisms research
- Advanced Nanomaterials in Catalysis
- Plant-Microbe Interactions and Immunity
- Hydrogels: synthesis, properties, applications
- Plant Micronutrient Interactions and Effects
- Plant Disease Resistance and Genetics
- Plant tissue culture and regeneration
- Effects and risks of endocrine disrupting chemicals
- Electrochemical sensors and biosensors
- Polysaccharides Composition and Applications
- Advanced Materials and Mechanics
- Heavy metals in environment
Huazhong University of Science and Technology
2023-2025
Northwest A&F University
2022-2025
Affiliated Eye Hospital of Wenzhou Medical College
2025
Wenzhou Medical University
2025
Chinese Academy of Sciences
2012-2025
Tianjin Normal University
2012-2025
Ocean University of China
2025
Xinjiang University
2020-2025
Wuhan Botanical Garden
2017-2025
Shenzhen Institutes of Advanced Technology
2025
<p indent="0mm">Antibiotics have received extensive attention due to their sophisticated effects on human health and ecosystems. However, there is an extreme scarcity of information composition, content, geographic distribution, risk riverine antibiotics at a large spatial scale. Based systematic review over 600 pieces literature (1999–2021), we established global dataset containing more than 90,000 records covering 169 metabolites in surface water sediment across 76 countries. The...
The critical challenge for cancer vaccine-induced T-cell immunity is the sustained activation of antigen cross-presentation in antigen-presenting cells (APCs) with innate immune stimulation. In this study, it first discovered that clinically used magnetic contrast agents, iron oxide nanoparticles (IONPs), markedly augment type-I interferon (IFN-I) production profile stimulator genes (STING) agonist MSA-2 and achieve a 16-fold dosage-sparing effect human STING haplotype. Acid-ionizable...
Plant-derived Vitamin C (l-ascorbic acid (AsA)) is crucial for human health and wellbeing thus increasing AsA content of interest to plant breeders. In plants GDP-l-galactose phosphorylase (GGP) a key biosynthetic control step here evidence presented two new transcriptional activators GGP. measurement, transcriptomics, transient expression, hormone application, gene editing, yeast 1/2-hybrid, electromobility shift assay (EMSA) methods were used identify positively regulating transcription...
Abstract Cold stress seriously affects plant development, resulting in heavy agricultural losses. L-ascorbic acid (AsA, vitamin C) is an antioxidant implicated abiotic tolerance and metabolism of reactive oxygen species (ROS). Understanding whether how cold elicits AsA biosynthesis to reduce oxidative damage important for developing cold-resistant plants. Here, we show that the accumulation response a common mechanism conserved across kingdom, from single-cell algae angiosperms. We...
Hsp60 is an important component of defense mechanisms against diabetic myocardial injury; however, the cause reduction in myocardium remains unknown. After stimulation cardiomyocytes with high glucose vivo and vitro, significant up‐regulation miR‐1/miR‐206 post‐transcriptional modulation Hsp 60 were observed. Serum response factor (SRF) MEK1/2 pathway involved miR‐1 miR‐206 expression cardiomyocytes. regulated post‐transcriptionally accelerated cardiomyocyte apoptosis through Hsp60. These...
Stem cell genetics research may be critical to our understanding of carcinogenesis, as both stem cells and cancer possess the ability self-renew. Recent discoveries have indicated that piwi family genes plays an essential role in self-renewal diverse organisms. The hiwi gene, human homolog family, participates germ proliferation its overexpression cause development malignancy, but expression function epithelial solid cancers not been explored. In present study, we investigated whether there...
To date, little is known about the effects of different light sources on growth and quality non-heading Chinese cabbage (Brassica campestris L.). The objective present study was to evaluate light-emitting diodes (LEDs) (blue, blue plus red, red), fluorescent lamps sunlight vitamin C, soluble protein, sucrose, sugar, starch pigment concentrations in seedlings. dry mass shoots fresh masses roots were highest seedlings grown under red LEDs with weak lights. concentration despite altered...
The chloroplast structural alteration and the photosynthetic apparatus activity of cherry tomato seedlings were investigated under dysprosium lamp [white light control (C)] six light-emitting diode (LED) treatments designated as red (R), blue (B), orange (O), green (G), (RB), red, blue, (RBG) with same photon flux density ( PPFD ) (≈320 μmol·m −2 ·s −1 for 30 days. Compared C treatment, net photosynthesis leaves was increased significantly B, RB, RBG reduced R, O, G. Chloroplasts RB...
Poly(acrylic acid) (PAA) hydrogels with superior mechanical properties, based on a single network structure dual cross-linking, are prepared by one-pot free radical polymerization. The of the PAA is composed cross-linking: dynamic and reversible ionic cross-linking among chains enabled Fe3+ ions, sparse covalent cross-linker (Bis). Under deformation, covalently cross-linked remain intact to maintain their original configuration, while Fe3+-enabled broken dissipate energy then recombined. It...
Rapeseed (Brassica napus L.) is sensitive to light quality. The factory production of rapeseed seedlings for vegetable use and transplanting in the field requires an investigation responses This study evaluated leaf (cv. 'Zhongshuang 11') different ratios red-photonflux (RPF) blue-photonflux (BPF) from emitting diodes (LEDs). treatments were set as monochromatic lights, including 100R:0B% 0R:100B%, compound lights (CLs), 75R:25B%, 50R:50B% 25R:75B%. total photonflux all was 550 μmolm-2s-1....
Membrane lipid composition associates closely with membrane stability and fluidity under water stress. In this study, lipidomic analyses based on electrospray ionization mass spectrometry (ESI-MS/MS) were carried out to explore dynamic changes of lipids in term molecular species caused by PEG (Polyethylene glycol-6000)-induced stress wheat seedlings.Among the main phospholipids, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylglycerol (PG) are primary degradation...
Kiwifruit is a recently domesticated horticultural fruit crop with substantial economic and nutritional value, especially because of the high content vitamin C in its fruit. In this study, we de novo assembled two telomere-to-telomere kiwifruit genomes from Actinidia chinensis var. 'Donghong' (DH) latifolia 'Kuoye' (KY), total lengths 608 327 852 640 561 626 bp for 29 chromosomes, respectively. With burst structural variants involving inversion, translocations, duplications within 8.39...
In this research, the ultrasound-assisted extraction (UAE) conditions of water-soluble polysaccharide (FCPS) from Ficus carica fruits were optimized using response surface methodology. The optimal FCPS yield was 7.97 % achieved by conducting four times at a solid–liquid ratio 1:20 (g/mL) and an ultrasound temperature 70 °C. Then, structure, antioxidant properties, hypoglycemic effects, immunomodulatory activities evaluated. characterized as irregular, rough-surfaced, flaky materials...
External environments (e.g., pollutants, irritants, ultraviolet radiation, etc) probably activate oxidative stress on the ocular surface, further leading to inflammatory responses and cellular apoptosis. For treating ophthalmic diseases, one of strategies is regulate through antioxidants. Here we conjugate a polyphenolic antioxidant drug (i.e., caffeic acid) with small peptide protein tag generate peptide‐drug as nanodrug. With self‐assembled ability form nanoparticles, nanodrug mainly...
ABSTRACT Targeted gene disruption studies in the mouse have demonstrated crucial roles for Brn3 POU domain transcription factor genes, Brn3a, Brn3b, Brn3c (now called Pou4f1, Pou4f2, Pou4f3, respectively) sensorineural development and survival. During retinogenesis, Brn3b is expressed a large set of postmitotic ganglion cell precursors required their early terminal differentiation. In contrast, Brn3a which are later cells, appear to be dispensable development. To understand mechanism that...