A5100374029- Plant Molecular Biology Research
- Plant Genetic and Mutation Studies
- Phytochemicals and Antioxidant Activities
- Plant Stress Responses and Tolerance
- Neuroinflammation and Neurodegeneration Mechanisms
- Fungal Biology and Applications
- Magnetic and Electromagnetic Effects
- Bioactive Compounds in Plants
- Liver physiology and pathology
- Medicinal Plants and Neuroprotection
- Advanced Proteomics Techniques and Applications
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Meat and Animal Product Quality
- Liver Disease Diagnosis and Treatment
- Polysaccharides and Plant Cell Walls
- Traditional Chinese Medicine Studies
- Remote Sensing and Land Use
- Plant nutrient uptake and metabolism
- HIV/AIDS drug development and treatment
- Chromosomal and Genetic Variations
- Healthcare and Venom Research
- Advanced Drug Delivery Systems
- Tea Polyphenols and Effects
- Neuroscience and Neuropharmacology Research
Hebei Agricultural University
2022-2025
Affiliated Hospital of Shaanxi University of Chinese Medicine
2023-2024
Xiangya Hospital Central South University
2024
Central South University
2024
Wuhan Institute of Technology
2023-2024
Delft University of Technology
2024
Northeast Agricultural University
2022-2024
Huzhou University
2022-2023
Ministry of Agriculture and Rural Affairs
2022-2023
Jiangsu Academy of Agricultural Sciences
2022-2023
Abstract Background MicroRNAs (miRNAs) are a new class of endogenous small RNAs that play essential regulatory roles in plant growth, development and stress response. Extensive studies miRNAs have been performed model plants such as rice, Arabidopsis thaliana other plants. However, the number discovered maize is relatively low little known about involved very early stage during seed germination. Results In this study, RNA library from 24 hours after imbibition was sequenced by Solexa...
Tetraspanins are commonly believed to act only as "molecular facilitators," with no direct role in signal transduction. We herein demonstrate that upon ligation, CD37, a tetraspanin molecule expressed on mature normal and transformed B cells, becomes tyrosine phosphorylated, associates proximal signaling molecules, initiates cascade of events leading apoptosis. Moreover, we have identified two residues opposing regulatory functions: one lies the N-terminal domain CD37 predicted "ITIM-like"...
Citrus is a kind of common fruit and contains multiple beneficial nutrients for human beings. Flavonoids, as class plant secondary metabolites, exist in citrus fruits abundantly. Due to their broad range pharmacological properties, flavonoids have gained increased attention. Accumulative vitro vivo studies indicate protective effects polymethoxyflavones (PMFs) against the occurrence cancer. PMFs inhibit carcinogenesis by mechanisms like blocking metastasis cascade, inhibition cancer cell...
Tea (Camellia sinensis) is widely considered to promote feelings of calming and soothing. This effect attributed L-theanine (L-γ-glutamylethylamide) in tea, a non-protein amino acid mainly derived from tea leaves. As naturally occurring structural analogue glutamate, competes for the receptors with glutamate able pass blood-brain barrier exert its relaxation effect. review focuses on L-theanine, including animal models latest human trials as well potential molecular mechanisms regarding...
Seed germination plays a pivotal role during the life cycle of plants. As dry seeds imbibe water, resumption energy metabolism and cellular repair occur miRNA-mediated gene expression regulation is involved in reactivation events. This research was aimed at understanding miRNA molecular control seed imbibition process. Small RNA libraries constructed from imbibed maize embryos were sequenced using Illumina platform. Twenty-four conserved families identified both libraries. Sixteen them...
Tropomyosin (TM) is the major allergen in clams. This study aimed to evaluate effects of ultrasound-assisted high temperature-pressure treatment on structure and allergenicity TM from The results showed that combined significantly affected TM-converting α-helix β-sheet random coil, decreasing sulfhydryl group content, surface hydrophobicity, particle size. These structural changes caused unfolding protein, disrupting modifying allergenic epitopes. significant reduction was approximately...
Salinity is a major abiotic stress that limits plant productivity and quality throughout the world. Roots are sites of salt uptake. To better understand responses in maize, we performed comparative proteomic analysis seedling roots from salt-tolerant genotype F63 salt-sensitive F35 under 160 mM NaCl treatment for 2 days. Under salinity conditions, shoot fresh weight relative water content were significantly higher than F35, while osmotic potential was lower reduction K+/Na+ ratio less...
Melanoma is among the most life-threatening cancers. The pathogenesis of melanoma has not been fully elucidated. Recently, dysregulated macroautophagy/autophagy found to play a critical but inconsistent role in modulating growth at different stages, with regulatory mechanism unclear. histone deacetylase SIRT6 (sirtuin 6) known autophagy regulator, and its involvement cancer development reported. Therefore, we sought determine detect possible link current study. We initially observed that...
Chestnut is one of China’s traditional export commodities in the international market and enjoys a positive reputation. Its key quality attributes are closely linked to changes physicochemical properties chestnut starch after thermal processing. This study investigated effects different temperatures (100 °C, 160 200 °C) times (10, 20, 30 min) dry heat treatment (DHT) on structural properties, as well functional starch. The results demonstrated that DHT increased solubility (S) water...
Atriplex prostrata Boucher, a facultative halophyte, exhibits significant reduction in height and biomass the width of cortex vascular tissue under saline conditions. Therefore, goal this investigation was to determine effect salinity on plant growth as well patterns lignification, peroxidase activity, extensin deposition. Biomass, leaf area, internode length, water potential, photosynthesis, transpiration, ion content were measured. In addition, lignin, peroxidase, were, respectively,...
Fatty acid (FA) composition of total lipids (TL) and phospholipids (PL) in breast milk obtained from 20 normal delivery healthy women Tokyo, Japan was analyzed. Total were extracted the samples then PL, consisting phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS), sphingomyelin (Sph) phosphatidylinositol (PI), separated by two-dimensional thin-layer chromatography. The FA TL PL analyzed gas liquid-chromatography. Compared with previous reports, contents...
The aim of the study was to develop a novel bioactive calcium alginate edible film for meat products based on antioxidant and antimicrobial properties Tinospora cordifolia, newly proposed ingredient. Goat sausages were utilized as model system analyse efficacy developed films with different concentration T. cordifolia viz. 0.0% (T1), 0.50% (T2), 1.0% (T3) along control (without film). Significant (p < 0.05) lower values observed thiobarbituric acid reacting substances (mg malonaldehyde/kg),...
Hyperoside, an active compound found in plants of the genera Hypericum and Crataegus , is reported to exhibit antioxidant, anticancer, anti-inflammatory activities. Induction hepatic stellate cell (HSC) apoptosis recognized as a promising strategy for attenuation fibrosis. In this study, we investigated whether hyperoside treatment can exert antifibrotic effects human LX-2 cells. We that induced cells decreased levels α -smooth muscle actin ( -SMA), type I collagen, intracellular reactive...
Increasing health-promoting effects of resveratrol and its molecular structural analogues have been discovered, the acting mechanism has explored. However, activity comparison such compounds in targeting macrophage-related inflammation associated with neurodegenerative diseases remains untouched. In this study, we evaluated activation polarization transition lipopolysaccharide (LPS)-stimulated BV-2 mouse microglial macrophages exposed to (RES) pterostilbene (PTE), oxyresveratrol (ORES),...
The phenolics from sea buckthorn (SP) exert various physiological functions. This study examined the interactions of SP on digestive and physicochemical properties rice (RS) wheat starch (WS), as well stability starch-phenolics during digestion. predominant were syringic acid (22.14%), gallic (15.23%), catechin (11.45%). addition manipulated rheology pastes affected rearrangement multi-scale structures gels. Fourier transform infrared spectroscopy X-ray diffraction revealed that interacted...
Acute liver injury resulting from several factors such as medication, food toxins, and herbal supplementation often leads to a severe health condition makes treatment difficult; thereby, the prevention of acute remains critical issue is great importance. In this study, we investigated preventive effects nobiletin (NOB) on mouse model concanavalin A (ConA)-induced injury. We observed that NOB (10 mg/kg) pretreatment ConA-treated mice significantly lowered levels enzymes including alanine...
Mushrooms contain multiple bioactive compounds of which dietary fibre is a representative type. Fortification extracted or naturally derived in staple starchy foods constitutes strategy to increase intake terms cardiovascular disease and other metabolic diseases. Food matrix viewed as physical domain containing nutrients interactions behaviours are different from those isolation free state. The nutritional effect mushrooms' addition the food reviewed together with alterations cooking...
Auricularia cornea var. Li. polysaccharide (ACP) has many important biological activities and potential application value in food engineering, pharmaceutical science, health care. The results were as follows: the extraction rate of ACP was 28.18% ± 1.41% purity 86.92% 2.80%. contains mannitol 32.41%, glucuronic acid 6.96%, rhamnose 0.32%, glucose 42.35%, galactose 0.77%, xylose 16.83%, fucose 0.36%, without galacturonic arabinose. In addition, an animal test diabetes mellitus II (DM II) with...
Diabetes has been listed as one of the three major diseases that endanger human health. Accurately injecting insulin (Ins) depending on level blood glucose (LBG) is standard treatment, especially controlling LBG in long-term by a single injection. Herein, pH-responsive hexa-histidine metal assembly (HmA) encapsulated with enzymes (GOx and CAT) Ins (HmA@GCI) engineered vehicle for glucose-mediated delivery. HmA not only shows high proteins loading efficiency, but also well retained activity...