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Research Areas
- Cardiomyopathy and Myosin Studies
- Cardiac tumors and thrombi
- Cardiovascular Effects of Exercise
The University of Texas Health Science Center at Houston
2022
Arrhythmogenic cardiomyopathy (ACM) is hereditary caused by pathogenic variants (mutations) in genes encoding the intercalated disc (ID), particularly desmosome proteins. ACM mutations DSP gene desmoplakin (DSP) characterized prominence of cell death, myocardial fibrosis, and inflammation, referred to as cardiomyopathy.The aim this article was gain insight into pathogenesis Dsp exclusively deleted cardiac myocytes using tamoxifen-inducible MerCreMer (Myh6-McmTam) floxed (DspF/F) mice...
10.20517/jca.2022.34
article
EN
The Journal of Cardiovascular Aging
2022-01-01
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