The objective of this work was to review comparisons the efficacy 68Ga-PSMA-11 (prostate-specific membrane antigen) PET/CT and multiparametric magnetic resonance imaging (mpMRI) in detection prostate cancer among patients undergoing initial staging prior radical prostatectomy or experiencing recurrent cancer, based on histopathological data. A comprehensive search conducted PubMed Web Science, relevant articles were analyzed with various parameters, including year publication, study design,...

This research aimed to measure the received photon and thermal neutron doses contralateral breast (CB) in cancer radiotherapy for various field sizes presence of physical dynamic wedges. The measurement was carried out on right region RANDO phantom (as CB) 18 MV beams. dose measurements were performed by thermoluminescent dosimeter chips. These obtained findings this study showed that (both neutron) CB wedge 11 × 13, 17 21 cm2 5.92, 6.36 6.77% prescribed dose, respectively as well 2.92, 4.63...

In the current study, we aimed to mitigate radiation-induced small intestinal toxicity using post-irradiation treatment with nano-micelle curcumin.Small intestine is one of most radiosensitive organs within body. Wholebody exposure an acute dose ionizing radiation may lead severe injuries this tissue and even cause death after some weeks.This study evaluate histopathological changes in following whole-body irradiation nanocurcumin.Forty male Nordic Medical Research Institute mice were...

This study was aimed at determining the effects of alpha-lipoic acid on ionizing irradiation-induced oxidative damage and apoptosis in brain rats.The animals were exposed to whole-brain X-radiation with a 15 Gy single dose absence or presence (200 mg/kg body weight) pretreatment for one week. The rats divided into four groups (5 each group): vehicle control, alone (ALA), radiation (RAD), plus (RAD+ALA). In next stage, malondialdehyde (MDA), nitric oxide, catalase (CAT), superoxide dismutase...

Spermatogenesis system is one of the most radiosensitive organs in body. A usual therapeutic dose radiation such as conventional 2 Gy each fraction radiotherapy and lower doses seen diagnostic radiology or a disaster affect process spermatogenesis potently. Selenium zinc are two important elements playing key roles development sperms also have radioprotective effects.In this study aims to evaluate effect selenium against radiation-induced mice testis injury.In experimental study, 30 were...

Background: Although radiotherapy is a common choice for cancer therapy, various types of toxicities in irradiated normal tissues limit the received dose by tumor cells. The gastrointestinal tract one most sensitive organs to detrimental effects radiation. As result high ionizing radiation, acute morphological changes intestine are observed within days weeks. Objectives: In this study, we aimed evaluate protective metformin against radiation-induced small injury. Methods: experimental used...

Coronavirus disease 2019 (COVID-19) is an acute respiratory illness caused by novel coronavirus SARS-CoV-2. The clinical manifestations of this infection have a range and typically include impairment smell, taste disturbance, cough, fever, shortness breath. Gastrointestinal been reported in anywhere from 3% to 50% patients with concomitant SARS-CoV-2 pulmonary infection. Abnormalities coagulation markers hospitalized COVID-19. During article, we will introduce patient COVID 19 but the most...

One of the treatment modalities for thyroid cancer and hyperthyroidism is radioiodine-131 (I-131) therapy. The use this therapeutic modality not completely safe can lead to oxidative stress, eventually DNA damages. However, these radiation-induced damages be reduced by antioxidants. This study aimed investigate potential radioprotective effects melatonin selenium nanoparticles (SeNPs) on double-stranded breaks (DSBs) caused I-131.After obtaining informed consent, 6 ml blood was taken from...

The current study aimed to investigate the potential role of melatonin in mitigation radiation-induced gastrointestinal injury.Organs system such as intestines, colon, duodenum, ileum etc. are sensitive ionizing radiation. Mitigation injury is an interesting topic radiobiology and a life-saving approach for exposed persons after radiation event or improving quality life radiotherapy patients.The find possible effect on damage small large intestines.40 male mice were randomly assigned into...

The present study aimed to assess the effects of extremely low-frequency electromagnetic fields (ELF-MF) on structural changes human osteosarcoma cells by analyzing stained cytoskeleton for assessing relationship between fractal dimension parameter and proliferation rate radiation-induced cells.In this study, 2-mT magnetic with various waveforms, including sinusoidal, triangular, pulsed shapes, were employed determine biological ELF-EMF MG-63 cell line. All experiments performed in two...

Secondary cancer risk estimation following prostate radiotherapy through gEUD concept and NCRP-116 recommendations

<title>Abstract</title> Background and Objectives: Recent advancements in artificial intelligence (AI), particularly through convolutional neural networks (CNNs), have led to significant progress tumor detection classification systems. This study aims train evaluate the performance of four distinct CNN models for 4-way glioma, meningioma, pituitary tumors, non-tumor magnetic resonance images (MRI). Methods Data augmentation techniques were applied MRI slices from Figshare, Br35H, Brain Tumor...

Background: Radiotherapy, a highly effective method of radiation-based treating cancers, can reduce the size tumors and affect healthy tissues. Radiation-induced lymphopenia as side effect radiation therapy effectiveness treatment.Objective: This study aimed to examine how taurine protect peripheral blood lymphocytes from apoptosis.Material Methods: In this experimental study, effects on were studied, samples divided into three groups: negative control group that was not treated, positive...

Lung lesions can increase the CT number and affect water-equivalent diameter (Dw), Dw-based conversion factor (CFw), size-specific dose estimate (SSDEw). We evaluated effect of COVID-19 total severity score (TSS) on radiation considering automatic tube current modulation (ATCM) fixed (FTC). A 186 chest scans were categorised into five TSS groups, including healthy, minimal, mild, moderate severe. The effective (Deff), Dw, CFw, Deff-based (CFeff), volume computed tomography index (CTDIVol),...