Abstract Background Uncomplicated urinary tract infection (uUTI) is predominantly caused by Escherichia coli, which has increasing antimicrobial resistance (AMR) at the United States (US)-community level. As uUTI often treated empirically, assessing AMR challenging, and there are limited contemporary data characterizing period prevalence in US. Methods This was a retrospective study of using Becton, Dickinson Company Insights Research Database (Franklin Lakes, New Jersey, US) collected...

Abstract Background Antimicrobial resistance research in uncomplicated urinary tract infection typically focuses on the main causative pathogen, Escherichia coli ; however, little is known about antimicrobial burden of Klebsiella species, which can also cause infections. This retrospective cohort study assessed prevalence and geographic distribution among species trends for K. pneumoniae United States (2011–2019). Methods oxytoca urine isolates (30-day, non-duplicate) female outpatients...

Abstract Background While many studies address the clinical management of participants with uncomplicated urinary tract infection (uUTI), emotional impact uUTIs has been investigated less often. The aim this qualitative study was to understand experience women uUTIs. Methods This a qualitative, exploratory, in-depth interview-based conducted among in United States (US) and Germany. Women aged ≥ 18 years at least one uUTI treated antibiotics past year were recruited through patient community...

Abstract Real-world data were collected to examine antimicrobial resistance (AMR) prevalence, treatment patterns, and clinical outcomes among female patients with uncomplicated urinary tract infection (uUTI) in Germany. Data from a retrospective physician-based chart review completed by physicians treating uUTI. Non-pregnant women aged ≥ 12 years, uUTI diagnosis, an E. coli- positive urine culture between January 2017–December 2019, susceptibility test results for 4 drug classes eligible....

Abstract Background Uncomplicated urinary tract infections (uUTIs), usually caused by Escherichia coli (E. coli), are common infections, affecting ∼50% of women globally in their lifetime. The presence extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales limits effective oral treatment options for uUTI. Using uropathogen susceptibility data from two randomized controlled trials (RCTs) uUTI, we compared baseline characteristics patients with ESBL-positive (ESBL+) versus non-ESBL...

Abstract Background Acute cystitis in men is classified as complicated urinary tract infection (UTI), despite the absence of functional and/or structural anatomical abnormalities tract, associated with a higher risk treatment failure. We conducted systematic literature review (SLR) to identify and summarize evidence on epidemiology (incidence, etiology, antimicrobial resistance [AMR], recurrence) patterns acute or afebrile UTI among no signs systemic infection. Methods Systematic searches...

Background Uncomplicated urinary tract infections (uUTIs) affect more than half of women in their lifetime and can impact on quality life. We analyzed social media posts discussing uUTIs to gather insights into the patient experience, including aspects disease management journey associated opinions concerns. Objective This study aims experience by analyzing that discussed uUTI. Methods A search string (“urinary infection” [UTI] or “bladder “cystitis” “UTI” not “interstitial cystitis”) was...

Infection by Aspergillus species causes a wide spectrum of pulmonary disease in humans. In two patients with semi-invasive Aspergillus-induced lung disease, significantly reduced levels interferon-γ secretion peripheral blood mononuclear cells were found after vitro stimulation the T-cell mitogen phytohaemagglutinin. Despite anti-fungal therapy, both exhibited progressive and adjunctive therapy was associated significant clinical improvement. The data suggest that impaired production can be...

Abstract Background Increasing antimicrobial resistance makes treating uncomplicated urinary tract infections (uUTIs) difficult. We compared whether adverse short-term outcomes among US female patients were more common when initial therapy did not cover the causative uropathogen. Methods This retrospective cohort study used data from outpatients aged ≥12 years, with a positive urine culture and dispensing of an oral antibiotic ±1 day index culture. Isolate susceptibility to initially...

Asthma and allergic rhinitis (AR) frequently coexist, having both asthma AR is associated with uncontrolled a heavier disease burden. The Asia-Pacific Survey of Physicians on Allergic Rhinitis (ASPAIR) aimed to assess physicians' perceptions their management practices for patients coexistent disease.A total 1,204 general physicians pediatricians from six countries in Asia, who routinely treat patients, were interviewed in-person. questioned about attitudes beliefs asthma-AR, how they...

Abstract Background Uncomplicated urinary tract infections (uUTIs) are one of the most common community-acquired infections, particularly among women. Common symptoms UTI include dysuria, urgency and increased frequency, lower abdominal pain. With appropriate treatment, may resolve in a few days. However, there is lack research on emotional impact this disease. We conducted qualitative, interview-based study to gain greater understanding uUTIs women China Japan. Methods A exploratory,...

Urinary tract infections (UTIs) caused by antimicrobial-resistant Enterobacterales are a global health threat. There limited surveillance data available to characterize the prevalence of antimicrobial resistance among outpatients in United States (US).

Background Uncomplicated urinary tract infections (uUTIs) are common bacterial infections. Aim Evaluate the burden of uUTI in England for 1) potential determinants disease progression; 2) extent and impact antimicrobial prescribing non-concordant with treatment guidelines; 3) economic costs. Design & setting Retrospective cohort study utilising patient data from Clinical Practice Research Datalink (CPRD) linked to English Hospital Episodes Statistics. Method Female patients aged≥12 years...

Antimicrobial resistance is an urgent global healthcare concern. Beyond carbapenems as broad-spectrum, often 'last resort' antibiotics, oral penem antibiotics currently are approved only in Japan and India, used for the treatment of indications including urinary tract infections (UTIs). Exploring use to better understand impact antibiotic on public health would help inform management infectious diseases, UTIs.This scoping review investigated faropenem other penems Enterobacterales infection...

Background: In China, the prevalence of allergic rhinitis (AR) and asthma has increased in past decade. As these two diseases frequently coexist, Asia-Pacific Survey Physicians on Asthma Allergic Rhinitis (ASPAIR) study aimed to assess physicians’ beliefs treatment patterns coexistent asthma-AR across six Asian countries. This analysis presents results from China. Methods: The 200 hospital-based general physicians pediatricians were interviewed five cities questioned in-person about their...

Background Underdiagnosis and undertreatment of allergic rhinitis (AR) in patients with asthma can worsen treatment outcomes. There is limited evidence clinical practices for management coexistent AR-asthma Thailand. Methods A multicountry, cross-sectional study (Asia-pacific Survey Physicians on Asthma Rhinitis) to evaluate physician perceptions related overlap 6 Asian countries was conducted. For Thailand specifically, linkage questionnaires were developed translated Thailaland. General...

<h3>Objectives</h3> According to NHS QOF (Quality and Outcomes Framework) figures, 3.3 million UK citizens have asthma. Previous studies shown an association of asthma with increased direct indirect healthcare costs, but similar not been conducted specifically for patients. The aim the current study is assess impact poor control on patients treated ICS + LABA maintenance treatment. <h3>Methods</h3> Data were from 2010 2011 National Health Wellness Survey (NHWS), Internet-based questionnaire...

The aim was to study the quality of care at a dia betic clinic large hospital in Sri Lanka; sam ple 200 patients randomly selected. A ques tionnaire designed assess patient knowledge diabetic management and service provision. Clinic attendance records were also used. Measures outcome taken be (i) patient's level understanding their condition, (ii) avail ability diagnostic tests, (iii) provision reg ular screening (iv) length consultation time. average each four-hour 174 patients. With three...