Sumanth Gandra

ORCID: 0000-0003-1482-0854
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About
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Research Areas
  • Antibiotic Use and Resistance
  • Antibiotic Resistance in Bacteria
  • Bacterial Identification and Susceptibility Testing
  • Pneumonia and Respiratory Infections
  • Antibiotics Pharmacokinetics and Efficacy
  • Global Maternal and Child Health
  • Pharmaceutical Practices and Patient Outcomes
  • COVID-19 Clinical Research Studies
  • Pharmaceutical Economics and Policy
  • Biosensors and Analytical Detection
  • Patient Satisfaction in Healthcare
  • Nosocomial Infections in ICU
  • Sepsis Diagnosis and Treatment
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Urinary Tract Infections Management
  • Antimicrobial Resistance in Staphylococcus
  • Clostridium difficile and Clostridium perfringens research
  • Advanced biosensing and bioanalysis techniques
  • Infection Control in Healthcare
  • COVID-19 epidemiological studies
  • Advanced Biosensing Techniques and Applications
  • Streptococcal Infections and Treatments
  • Mycobacterium research and diagnosis
  • Tuberculosis Research and Epidemiology
  • Fungal Infections and Studies

Washington University in St. Louis
2019-2024

New York Proton Center
2024

Communities In Schools of Orange County
2024

University of Pittsburgh
2024

Lindsay Unified School District
2024

Oregon Medical Research Center
2024

Milliken & Company (United States)
2024

Jewish Hospital
2023

Barnes-Jewish Hospital
2023

University of Massachusetts Chan Medical School
2013-2022

10.1016/s1473-3099(17)30753-3 article EN The Lancet Infectious Diseases 2017-12-21

Significance Antibiotic resistance, driven by antibiotic consumption, is a growing global health threat. Our report on use in 76 countries over 16 years provides an up-to-date comprehensive assessment of trends consumption. We find that the consumption rate low- and middle-income (LMICs) has been converging to (and some surpassing) levels typically observed high-income countries. However, inequities drug access persist, as many LMICs continue be burdened with high rates infectious...

10.1073/pnas.1717295115 article EN cc-by Proceedings of the National Academy of Sciences 2018-03-26

Understanding of the factors driving global antimicrobial resistance is limited. We analysed and antibiotic consumption worldwide versus many potential contributing factors.Using three sources data (ResistanceMap, WHO 2014 report on resistance, contemporary publications), we created two indices for 103 countries using from 2008 to 2014: Escherichia coli resistance-the average prevalence E bacteria that were resistant third-generation cephalosporins fluoroquinolones, aggregate combined...

10.1016/s2542-5196(18)30186-4 article EN cc-by-nc-nd The Lancet Planetary Health 2018-08-31

Rising rates of antimicrobial resistance (AMR) globally continue to pose agrave threat human health. Low- and middle-income countries (LMICs) are disproportionately affected, partly due the high burden communicable diseases.We reviewed current trends in AMR LMICs examined forces driving those regions. The state interventions being undertaken curb across developing world discussed, impact COVID-19 pandemic on efforts is explored.The dynamics that drive inseparable from political, economic,...

10.1080/14787210.2021.1951705 article EN Expert Review of Anti-infective Therapy 2021-07-06

Abstract Background The threat posed by antibiotic resistance is of increasing concern in low- and middle-income countries (LMICs) as their rates use increase. However, an understanding the burden lacking LMICs, particularly for multidrug-resistant (MDR) pathogens. Methods We conducted a retrospective, 10-hospital study relationship between MDR pathogens mortality India. Patient-level antimicrobial susceptibility test (AST) results Enterococcus spp., Escherichia coli, Staphylococcus aureus,...

10.1093/cid/ciy955 article EN cc-by Clinical Infectious Diseases 2018-11-07

Guidance on the appropriate use of antibiotics for common infections is lacking in many settings. The World Health Organization (WHO) has recently released WHO AWaRe (Access, Watch, Reserve) antibiotic book which complements Model list essential medicines and children. gives specific guidance empiric model lists with a strong emphasis framework, centred around risk antimicrobial resistance development associated different antibiotics. Recommendations cover 34 primary hospital care both...

10.2471/blt.22.288614 article CA Bulletin of the World Health Organization 2023-04-01

Background We assessed the impact of coronavirus disease 2019 (COVID-19) epidemic in India on consumption antibiotics and hydroxychloroquine (HCQ) private sector 2020 compared to expected level use had not occurred. Methods findings performed interrupted time series (ITS) analyses sales volumes reported standard units (i.e., doses), collected at regular monthly intervals from January 2018 December obtained IQVIA, India. As children are less prone develop symptomatic severe acute respiratory...

10.1371/journal.pmed.1003682 article EN cc-by PLoS Medicine 2021-07-01

The WHO Model List of Essential Medicines (EML) prioritizes medicines that have significant global public health value. EML can also deliver important messages on appropriate medicine use. Since 2017, in response to the growing challenge antimicrobial resistance, antibiotics were reviewed and categorized into three groups: Access, Watch Reserve, leading a new categorization called AWaRe. These categories developed taking account impact different classes implications for their 2023 AWaRe...

10.1016/j.cmi.2024.02.003 article EN cc-by Clinical Microbiology and Infection 2024-02-09

There have been no long-term studies on trends in antibiotic resistance (ABR) a national scale India. Using private laboratory network, the ABR patterns of organisms most commonly associated with bacteremia, obtained from patients across India between 2008 and 2014, were examined.A retrospective study patient blood cultures collected over 7-year period (January 1, 2008-December 31, 2014) was conducted. Data microorganism(s) identified their antimicrobial susceptibility SRL Diagnostics...

10.1016/j.ijid.2016.08.002 article EN cc-by International Journal of Infectious Diseases 2016-08-11

The prevalence of carbapenem-resistant Enterobacteriaceae (CRE) infections is increasing in the United States. However, few studies have addressed their epidemiology children. To phenotypically identify CRE isolates cultured from patients 1-17 years age, we used antimicrobial susceptibilities reported to 300 laboratories participating Surveillance Network-USA database during January 1999-July 2012. Of 316,253 analyzed, 266 (0.08%) were identified as CRE. infection rate increases highest for...

10.3201/eid2111.150548 article EN cc-by Emerging infectious diseases 2015-10-14
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