A5071336978- Child Nutrition and Water Access
- Viral gastroenteritis research and epidemiology
- Parasitic Infections and Diagnostics
- Parasites and Host Interactions
- Amoebic Infections and Treatments
- Dental Research and COVID-19
- Zoonotic diseases and public health
- Global Maternal and Child Health
- Birth, Development, and Health
- Parasite Biology and Host Interactions
- Hepatitis Viruses Studies and Epidemiology
- Food Security and Health in Diverse Populations
- Healthcare professionals’ stress and burnout
- Infant Nutrition and Health
- Wastewater Treatment and Reuse
- Dental Health and Care Utilization
- Endodontics and Root Canal Treatments
- Cardiovascular Effects of Exercise
- HIV-related health complications and treatments
- Breastfeeding Practices and Influences
- Safety Warnings and Signage
- Occupational exposure and asthma
- Antibiotic Use and Resistance
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac electrophysiology and arrhythmias
Christian Medical College, Vellore
2011-2024
Ragas Dental College & Hospital
2020-2023
Tamil Nadu Dr. M.G.R. Medical University
2020-2022
Christian Medical College
2011-2016
Tufts University
2014
Tufts Medical Center
2011
Stunting or reduced linear growth is very prevalent in low-income countries. Recent studies have demonstrated a causal relationship between alterations the gut microbiome and moderate severe acute malnutrition children these However, there been no primary longitudinal comparing intestinal microbiota of persistently stunted to that non-stunted same community. In this pilot study, we characterized microbial community composition diversity fecal 10 with low birth weight persistent stunting...
Objective To estimate the burden and assess prenatal postnatal determinants of illnesses experienced by children residing in a semiurban slum, during first 1000 days life. Design Community-based birth cohort Setting Southern India Participants Four hundred ninety-seven 561 pregnant women recruited followed for 2 years with surveillance anthropometry. Main outcome measure Incidence rates illness; clinic visits hospitalisations; factors associated low weight, various growth. Results Data on 10...
ABSTRACT Diarrhea causes significant morbidity and mortality in Indian children under 5 years of age. Flies carry enteric pathogens may mediate foodborne infections. In this study, we characterized fly densities as a determinant infectious diarrhea longitudinal cohort 160 urban 80 rural households with 1,274 individuals (27% age) Vellore, India. Household questionnaires on living conditions were completed at enrollment. Fly abundance was measured during the wet dry seasons using ribbons...
Abstract The study examined relationships among meteorological parameters, water quality and diarrheal disease counts in two urban three rural sites Tamil Nadu, India. Disease surveillance was conducted between August 2010 March 2012; concurrently samples from street-level taps piped distribution systems household storage containers were tested for pH, nitrate, total dissolved solids fecal coliforms. Methodological advances data collection (concurrent prospective environmental monitoring)...
Background Hookworms (Necator americanus and Ancylostoma duodenale) remain a major public health problem worldwide. Infections with hookworms (e.g., A. caninum, ceylanicum braziliense) are also prevalent in dogs, but the role of dogs as reservoir for zoonotic hookworm infections humans needs to be further explored. Methodology/Principal Findings As part an open-label community based cluster-randomized trial tribal area Tamil Nadu (India; 2013–2015), total 143 isolates eggs from human stool...
To estimate the prevalence, spatial patterns and clustering in distribution of soil-transmitted helminth (STH) infections, factors associated with hookworm infections a tribal population Tamil Nadu, India.Cross-sectional study one-stage cluster sampling 22 clusters. Demographic risk factor data stool samples for microscopic ova/cysts examination were collected from 1237 participants. Geographical information systems mapping assessed infection.The overall prevalence STH was 39% (95% CI...
The risk factors for acquisition of cryptosporidial infection in resource-poor settings are poorly understood. A nested case-control study was conducted to assess associated with childhood cryptosporidiosis (detected by stool polymerase chain reaction) an endemic, Indian slum community using data from two community-based studies 580 children followed prospectively until their second birthday. Factors were assessed overall (N = 406), and multiple 208), asymptomatic 243), symptomatic 163)...
Introduction Socioeconomic status (SES) scales measure poverty, wealth and economic inequality in a population to guide appropriate public health policies. Measurement of poverty comparison material deprivation across nations is challenge. This study compared four SES which have been used locally internationally evaluated them against childhood stunting, as an indicator chronic deprivation, urban southern India. Methods A door-to-door survey collected information on socio-demographic...
Introduction CD44, a multistructural and multifunctional transmembrane glycoprotein, is promising cancer stem cell (CSC) marker that regulates the properties of CSCs, including self-renewal, tumor initiation, metastasis, confers resistance to chemotherapy radiotherapy. The aim present study was evaluate gene protein expression CD44 explore its prognostic value in head neck squamous carcinoma (HNSCC). Methodology observational employs computational tools for analysis. Cancer Genome Atlas...
Cryptosporidium is a leading cause of moderate to severe childhood diarrhea in resource-poor settings. Understanding the natural history cryptosporidiosis and correlates protection are essential develop effective sustainable approaches disease control prevention.Children (N = 497) were recruited at birth semiurban slums Vellore, India, followed for 3 years with twice-weekly home visits. Stool samples collected every 2 weeks during diarrheal episodes tested species by polymerase chain...
SUMMARY Diarrhoeal diseases are major causes of morbidity and mortality in developing countries. This longitudinal study aimed to identify controllable environmental drivers intestinal infections amidst a highly contaminated drinking water supply urban slums villages Vellore, Tamil Nadu southern India. Three hundred households with children (<5 years) residing two semi-urban three were visited weekly for 12–18 months monitor gastrointestinal morbidity. Households surveyed at baseline...
It is generally assumed that hookworm infections in humans are caused by Necator americanus and Ancylostoma duodenale. However, previous studies have also reported the presence of animal A. ceylanicum human stools. We determined children a tribal community Tamil Nadu, India, using semi-nested PCR-RFLP approach. The results indicate species account for majority (N. 39/41 [95%]; duodenale 6/41 [15%]), whereas only accounts minority (5%; 2/41). emphasize need to consider zoonotic...
Welders in the unorganized occupational sector economically developing world are exposed to respiratory, skin, eye, ear, and neurological problems exacerbated by non-usage of personal protective equipment (PPE).To study frequency health usage PPE among welders welding units Vellore, India.A cross-sectional survey was conducted 150 determine respiratory morbidity PPE. A group non-welders were chosen for comparison.Significant differences skin burns, redness, hyper pigmentation, itching, eye...
The World Health Organization (WHO) has defined moderate-to-heavy intensity (M&HI) infections with soil-transmitted helminths (Ascaris lumbricoides, Trichuris trichiura and the two hookworms, Ancylostoma duodenale Necator americanus) based on specific values of eggs per gram stool, as measured by Kato-Katz method. There are a variety novel microscopy DNA-based methods but it remains unclear whether applying current WHO thresholds to these allows for reliable classification M&HI infections....
Background: Antibiotic treatment of childhood illnesses is common in India. In addition to contributing antimicrobial resistance, antibiotics might result increased susceptibility diarrhea through interactions with the gastrointestinal microbiota. Breast milk, which enriches microbiota early life, may increase resilience against perturbations by antibiotics. Methods: a prospective observational cohort study, we assessed whether antibiotic exposures from birth 6 months affected rates up age 3...
Background Antibiotics are commonly given for the treatment of childhood diarrhoea, but not indicated in most cases. modify gastrointestinal microbiota, which may have unanticipated effects on risk subsequent diarrhoea.
Cryptosporidium spp. is a common, but under-reported cause of childhood diarrhea throughout the world, especially in developing countries. A comprehensive estimate burden cryptosporidiosis resource-poor settings not available.We used published and unpublished studies to diarrhea, hospitalization mortality due cryptosporidial infections Indian children. Our estimates suggest that annually, one every 6-11 children <2 years age will have an episode 1 169-633 be hospitalized 2890-7247 die...
Background: Sudden cardiac arrest (SCA) requiring cardiopulmonary resuscitation (CPR) is one of the common emergencies encountered in emergency department (ED) any hospital. Although several studies have reported predictors CPR outcome general, there are limited data from EDs India. Materials and Methods: This retrospective study included all patients above 18 years with SCA who were resuscitated ED a tertiary care hospital an annual census 60,000 between August 2014 July 2015. A modified...
The common species and subgenotypes causing cryptosporidiosis were studied in 394 children 627 animals with diarrhea Vellore southern India. Although no zoonotic strains identified 13 infected children, 1 of 12 had C. hominis, indicating the potential for cross-species transmission. This study also reports xiaoi first time
ASBTRACT Background The novel 2019 coronavirus(COVID-19) spreads by respiratory and aerosols. COVID19 driven pandemic causes panic, fear stress among all strata of society. Like other medical professions, dentists, particularly endodontists, who are highly exposed to aerosols would be stress. aim this study was assess the (dis)stress Indian endodontists factors that could influence (dis)stress. Methods From 8 th April 16 2020, we conducted an online survey in closed endodontic social media...