A5003034392- Natural Antidiabetic Agents Studies
- Drug-Induced Hepatotoxicity and Protection
- Ethnobotanical and Medicinal Plants Studies
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Biological Activities
- Antioxidant Activity and Oxidative Stress
- Pharmacology and Obesity Treatment
- Morinda citrifolia extract uses
- Fungal Biology and Applications
- Phytochemicals and Antioxidant Activities
- Chemotherapy-induced cardiotoxicity and mitigation
- Natural product bioactivities and synthesis
- Seed and Plant Biochemistry
- Biochemical effects in animals
- Microbial bioremediation and biosurfactants
- Insect Utilization and Effects
- Cholesterol and Lipid Metabolism
- Pharmacological Effects of Medicinal Plants
- Bioactive Compounds and Antitumor Agents
- Biochemical Acid Research Studies
- Vitamin K Research Studies
- Moringa oleifera research and applications
- African Botany and Ecology Studies
- Therapeutic Uses of Natural Elements
- Hibiscus Plant Research Studies
University of Port Harcourt
2014-2023
The proximate and mineral profiles of the larva Oryctes rhinoceros were investigated. fatty acid profile larval oil amino protein also determined from latter, score was evaluated. A high content (42.29% wet weight) rich in essential acids (with histidine, methionine phenylalanine being predominant) with a 72.97% valine as limiting observed. had proportion (60.34%) unsaturated acids, including linoleic acid. ash (12.70% containing manganese iron (3.80 mg 100 gG 10.70 , respectively) 1 other...
Rutin (RUT) is an antioxidant flavonoid with well-known metal chelating potentials.This study was designed to evaluate the protective effects of RUT against cadmium (Cd) + ethanol (EtOH)-induced hepatic and renal toxicity in rats.Wistar rats were treated Cd (50 mg/kg) alone or combination EtOH (5 (25, 50 100 for 15 days. After treatment, liver, kidney serum removed biochemical assays by spectrophotometric methods.Serum, malondialdehyde (MDA) levels highest group lowest animals co-treated...
Abstract An aqueous leaf extract of Talinum triangulare was screened for the presence bioactive molecules, using gas chromatography coupled with pulse and flame ionization detectors. It had high carotenoids; moderate benzoic acid derivatives, hydroxycinnamates flavonoids; low terpenes, alkaloids, phytosterols, allicins, glycosides, saponins, lignans contents. Ten known carotenoids (mainly 50.42% carotene 33.30% lycopene), nine derivatives 84.63% ferulic 11.92% vanillic acid), six (55.44%...
The leaves of Tridax procumbens were screened for the presence bioactive molecules. They had high flavonoids, alkaloids, hydroxycinnamates, tannins and phytosterols, moderate benzoic acid derivatives lignans, low carotenoids contents. Thirty nine known alkaloids (mainly akuammidine, 68.756%), twenty three flavonoids 17.593% kaempferol 12.538% (-)-epicatechin), five lutein, 62.608%), four ferulic acid, 46.091%), two phytosterols stigmasterol, 80.853%) six lignans galgravin, 77.326%) detected....
The major draw-back of doxorubicin's use in chemotherapy is its toxicity on various organs including the kidneys. This study investigated potential protective role aqueous leaf-extracts Chromolaena odorata and Tridax procumbens against nephrotoxicity induced by doxorubicin.To this end, their impact plasma biomarkers kidney function, as well renal lipid profile, oxidative stress, electrolyte profile activities ATPases was monitored doxorubicin treated rats. Metformin (250 mg/kg body weight,...
The effect of aqueous extract the leaves Chromolaena odorata on body weight, organ sizes, lipid profiles and atherogenic indices was investigated in normal sub-chronic salt-loaded rats. treatment control groups were fed 100% commercial feed, while test control, reference received an 8% diet. (at 100 200 mg/kg weight) moduretics 1 orally administered daily. appropriate volumes water. screened for bioactive components using gas chromatography-coupled-flame ionization detector. main glycosides,...
Abstract The profile of phenolic compounds in the leaves and stems Pandiaka heudelotii was investigated using gas chromatography coupled with flame ionization detector. had high flavonoids benzoic acid derivatives content, moderate levels lignans hydroxycinnamates. Twenty‐eight known were detected, which consisted mainly kaempferol (41.93% 47.97% stems), (+)‐catechin (17.12% 16.11% quercetin (13.83% 9.39% luteolin (7.34% 7.71% artemetin (6.53% 4.83% stems). Of six hydroxycinnamates...
The proximate, minerals, vitamins, amino acid, alkaloids, phytosterols, carotenoids, glycosides and saponins profiles of the leaves stems Pandiaka heudelotii were determined using standard methods. had high contents (g/100g) fibre (10.3–12.9) carbohydrate (47.2–55.3); moderate protein (4.4–9.8) crude fat (6.7–10.2); respectively, equivalent to 41.1–51.6%, 15.7–17.8%, 8.8–19.6%, 10.3–15.7% corresponding daily values. They iron, manganese, calcium, magnesium, potassium, selenium, vitamins C, E...
To investigate the effects of an aqueous leaf extract Acalypha wilkesiana (A. wilkesiana) on plasma chemistry and hematological indices sub-chronic salt-loaded rats.The control group received a diet consisting 100% commercial feed, while four test groups were 8% salt 92% feed all through, except for reference treatment that had its salt-loading discontinued after six weeks. The was orally administered daily at 200 250 mg/kg body weight; control, appropriate volumes water by same route.The no...