A5073552185- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Infective Endocarditis Diagnosis and Management
- Virology and Viral Diseases
- Cystic Fibrosis Research Advances
- Probiotics and Fermented Foods
- Respiratory viral infections research
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
- Antibiotic Resistance in Bacteria
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- Microbial Metabolites in Food Biotechnology
- Actinomycetales infections and treatment
- Poxvirus research and outbreaks
- Streptococcal Infections and Treatments
- Genital Health and Disease
- Healthcare and Environmental Waste Management
- Immunodeficiency and Autoimmune Disorders
- Myasthenia Gravis and Thymoma
- Tracheal and airway disorders
- Pharmacovigilance and Adverse Drug Reactions
- Heparin-Induced Thrombocytopenia and Thrombosis
- Women's cancer prevention and management
- Criminal Justice and Corrections Analysis
Fundação Oswaldo Cruz
2025
Ministério da Saúde
2015-2024
Ministério da Saúde
2011-2023
Secretaria da Saúde
2022-2023
Governo do Distrito Federal
2022
Secretaria de Estado de Educação do Distrito Federal
2021
Universidade de Brasília
2015-2017
Universidade Federal de Viçosa
2011-2012
Fundação Estadual de Produção e Pesquisa em Saúde
2008
Routine infant immunization with meningococcal C conjugate (MCC) vaccination started in Brazil November 2010, scheduled at three and five months plus a booster 12–15 of age. No catch-up was implemented. We assessed the impact on disease (MenC) four years after start National Immunization Program. performed an ecological quasi-experimental design from 2008 to 2014 using deterministic linkage between Notification Reference Laboratory databases for meningitis. conducted interrupted time-series...
To evaluate the system for Health Surveillance of Populations Exposed to Chemical Substances (Vigipeq) in Brazil from 2011 2021. Qualitative attributes (simplicity; acceptability, or engagement individuals and institutions surveillance; flexibility; utility, achievement objectives) were assessed using a semi-structured anonymous questionnaire completed by representatives environmental health surveillance agencies capital cities. Quantitative attributes, including sensitivity (case...
Abstract Objective: to describe human papillomavirus (HPV) vaccination coverage in the Northeast region of Brazil, period from 2013 2021. Methods: this was a descriptive study conducted with data obtained National Immunization Program, which sets goal 80% HPV girls aged between 9 and 14 years boys 11 years. Results: 73.9%, regarding first dose, 54.3% second for boys, each dose 49.7% 32.6%, respectively; exception states Ceará Paraíba, reached above girls, none both doses. Conclusions: 2021,...
Summary Objective To describe the epidemiology of meningococcal disease (MD) in southern Brazil. Methods Retrospective cohort study among 2215 MD cases reported from 1995 to 2003 Rio Grande do Sul (RS) State. Results The overall incidence fell by 50%; case‐fatality rate during this period was 22%. Even so, remained high after epidemic ended 1999. Together, age groups 1–4 years and infants accounted for 54.1% with incidences 11.3/100 000 31.3/100 000, respectively; 69.8% were caused Neisseria...
The objective of this study was to analyze the impact vaccination against Streptococcus pneumoniae on morbidity and mortality from pneumococcal meningitis in children ≤ 2 years Brazil, 2007 2012. This is a descriptive ecological analysis using data Information System Notifiable Diseases. Pre-vaccination (2007-2009) post-vaccination (2011-2012) periods were defined compare incidence rates mortality. A total 1,311 cases 430 deaths reported during period. Incidence decreased 3.70/100,000...
To prevent secondary invasive meningococcal disease (IMD) cases and outbreaks, antimicrobial prophylaxis of high-risk contacts is indicated. This study reports two ciprofloxacin-resistant Neisseria meningitidis strains in Brazil. The 3523 N. isolates collected throughout Brazil from 2009 to 2016 were evaluated for resistance. Meningococcal showing minimal inhibitory concentrations, MICs≥0.125µg ml-1 ciprofloxacin, analysed determine the presence mutations quinolone resistance-determining...
SUMMARY An outbreak of meningococcal disease (MD) with severe morbidity and mortality was investigated in midwestern Brazil order to identify control measures. A MD case defined as isolation Neisseria meningitidis , or detection polysaccharide antigen a sterile site, presence clinical purpura fulminans, an epidemiological link laboratory-confirmed case-patient, between June August 2008. In 8 out 16 cases studied, serogroup C ST103 complex identified. Five (31%) had neurological findings five...
To describe the antimicrobial resistance profile of Neisseria meningitidis isolates causing invasive disease in Brazil from 2009 to 2016.Among 3548 N. received, 2888 (81.4 %) were analysed for using broth microdilution technique, as recommended by Clinical and Laboratory Standards Institute. Isolates tested ciprofloxacin, chloramphenicol, ceftriaxone, penicillin G, ampicillin rifampin.All susceptible while 953 (33.0 %), 1307 (45.3 2 (0.07 G-, ampicillin- rifampin-intermediate, respectively....
An outbreak of coronavirus disease began in a large penitentiary complex Brazil on April 1, 2020. By June 12, there were 1,057 confirmed cases among inmates and staff. Nine patients hospitalized, 3 died. Mean serial interval was ≈2.5 days; reproduction number range 1.0-2.3.
Meningococcal C conjugate (MenC) vaccine was introduced as part of the Brazilian National Immunisation Program in 2010 for children < 1 year age.The study objective to evaluate impact this vaccination strategy.An observational, mixed ecological and analytical conducted, based on time series panel data from surveillance records (2001-2013).A total 37,538 meningococcal disease cases were recorded during period. Of these, 19,997 attributed serogroup C. A decrease (MDC) incidence among aged...
to evaluate meningococcal disease (MD) surveillance from 2007-2017, according its attributes.this was a descriptive study of the 'timeliness', 'representativeness', 'simplicity', 'flexibility', 'data quality', 'acceptability' and 'usefulness' attributes system, based on Centers for Disease Control Prevention guidelines; we used National Notifiable Diseases Information System (SINAN) data, with onset symptoms between 2007-2017.the system found be complex eight case definitions six laboratory...
Invasive meningococcal disease (IMD) has a high rate of fatality and may cause severe clinical sequelae. Over the years, epidemiology IMD changed significantly in various regions world, laboratory surveillance this is important for mapping epidemiologic changes.To perform phenotypic characterization Neisseria meningitidis strains isolated from invasive Brazil 2002 to 2017, as complementation data obtained period 1990-2001.In total, 8,689 isolates sent Adolfo Lutz Institute confirmed N. by...
The recent licensure of two different serogroup B recombinant protein meningococcal vaccines in Brazil emphasizes the importance a better knowledge real burden (MenB) disease to establish evidence-based vaccination policies. We performed an observational, descriptive study, from 2001 2015, analyzing incidence and case fatality rates (CFR) MenB Brazil, according age group region. In absence any vaccine use targeting disease, significant decline 90% overall was observed (from 0.55...
To assess SARS-CoV-2 prevalence and health outcomes among inmates over 60 years during a COVID-19 outbreak in major penitentiary complex the Federal District, Brazil.A mass test campaign was performed on May 13, 2020, using antibody-detection rapid tests for asymptomatic reverse transcriptase-polymerase chain reaction testing those who were symptomatic. Those with negative results retested June 16. Inmates interviewed to characterise background conditions presence of symptoms.A total 159...
A basic requirement for the prediction of potential use lactic acid bacteria (LAB) in dairy industry is identification specific genes involved flavour-forming pathways. The probiotic Lactobacillus delbrueckii UFV H2b20 was submitted to a genetic characterisation and phylogenetic analysis protein catabolism. Eight belonging this system were identified, which possess closely relationship NCFM strains representative, as it demonstrated oppC oppBII , encoding oligopeptide transport components....
There are three main reasons for using lactic acid bacteria (LAB) as starter cultures in industrial food fermentation processes: preservation due to production; flavour formation a range of organic molecules derived from sugar, lipid and protein catabolism; probiotic properties attributed some strains LAB, mainly lactobacilli. The aim this study was identify genes involved lactose metabolism the Lactobacillus delbrueckii UFV H2b20, analyse its production during growth skimmed milk. following...
Introduction. Invasive meningococcal disease is a major health problem, impacting morbidity and mortality worldwide. Exploratory genomics has revealed insights into adaptation, transmissibility virulence to elucidate endemic, outbreaks or epidemics caused by Neisseria meningitidis serogroup W (MenW) strains.Gap Statement. Limited information on the of meningitis ST11/cc11 available from emerging countries, especially in contemporary isolates.Aim. To (i) describe antigenic diversity...
Os autores externos submeteram sua publicação para apresentação de trabalho no evento "International Symposium on Immunobiologicals", que foi coordenado e organizado pelo Instituto Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fundação Oswaldo Cruz.
This study aims to estimate the overall SARS-CoV-2 seroprevalence and evaluate accuracy of an antibody rapid test compared a reference serological assay during COVID-19 outbreak in prison complex housing over 13,000 prisoners Brasília.
Summary: The pandemic of COVID-19 has presented as a threat to prison systems worldwide, overcrowding, limited possibility social distancing and sanitary restrictions favouring viral spread. SARS-CoV-2 seroprevalence studies in settings are important tools understand transmission develop control measures. We aimed estimate the overall evaluated accuracy an antibody rapid test compared reference serological assay during outbreak complex housing over 13,000 inmates Brasília. Methods: conducted...
Introdução: Mpox é uma doença viral, declarada Emergência de Saúde Pública Importância Internacional entre 23 julho 2022 e 11 maio 2023. Apesar afetar qualquer indivíduo, as hospitalizações os óbitos concentram-se na população vivendo com HIV, globalmente no Brasil, destacando-se a necessidade gerar informações sobre ocorrência da nesse grupo para embasar ações prevenção controle âmbito do Sistema Único (SUS). Objetivo: Analisar casos confirmados em pessoas que vivem HIV e/ou...