A5084257942- Vaccine Coverage and Hesitancy
- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Virology and Viral Diseases
- Science and Education Research
- Public Health in Brazil
- Health, Nursing, Elderly Care
- Global Maternal and Child Health
- Hepatitis Viruses Studies and Epidemiology
- Hepatitis B Virus Studies
- Viral gastroenteritis research and epidemiology
- Mosquito-borne diseases and control
- Crime Patterns and Interventions
- Syphilis Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Child Nutrition and Water Access
- Cystic Fibrosis Research Advances
- Maternal and Neonatal Healthcare
- Food Security and Health in Diverse Populations
- Parvovirus B19 Infection Studies
- Child and Adolescent Health
- COVID-19 epidemiological studies
- Healthcare Regulation
- Youth, Drugs, and Violence
Faculdade de Ciências Médicas da Santa Casa de São Paulo
2015-2025
Fundação de Medicina Tropical
2024
Fundação Oswaldo Cruz
2024
Universidade Federal de Minas Gerais
2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2024
Universidade de São Paulo
2004-2022
Instituto de Saúde
2022
Irmandade da Santa Casa de Misericórdia de São Paulo
1997-2019
Governo do Estado de São Paulo
2016
Ministério da Saúde
2016
BackgroundButantan–Dengue Vaccine (Butantan-DV) is an investigational, single-dose, live, attenuated, tetravalent vaccine against dengue disease, but data on its overall efficacy are needed.MethodsIn ongoing phase 3, double-blind trial in Brazil, we randomly assigned participants to receive Butantan-DV or placebo, with stratification according age (2 6 years, 7 17 and 18 59 years); 5 years of follow-up planned. The objectives the were evaluate symptomatic, virologically confirmed any...
Background Since 1988, Brazil's Unified Health System has sought to provide universal and equal access immunisations. Inequalities in immunisation may be examined by contrasting vaccination coverage among children the highest versus lowest socioeconomic strata. The authors with routine infant immunisations from a survey of Brazilian according stratum residence census tract. Methods conducted household cluster tracts systematically selected five strata, average income head education, 26...
OBJECTIVE: To characterize patients of primary health care services according to demographic and socioeconomic aspects, habits lifestyle, condition, demand for medicines. METHODS: This study is part the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos – Serviços (PNAUM National Survey on Access, Use Promotion Rational Medicines Services), a cross-sectional carried out between 2014 2015. Interviews were conducted with over age 17 years, standardized...
Brazil implemented routine immunization with the human rotavirus vaccine, Rotarix, in 2006 and vaccination coverage reached 81% 2008 São Paulo. Our aim was to assess impact of on incidence severe acute gastroenteritis (AGE).We performed a 5-year (2004-2008) prospective surveillance at sentinel hospital Paulo, testing for all children less than 5 years age hospitalized AGE. Genotypes positive samples were determined by reverse transcription polymerase chain reaction.During study, 655 AGE...
ABSTRACT Despite almost universal use of measles vaccines in recent decades, epidemics the disease continue to occur. Understanding role primary vaccine failure (failure seroconvert after vaccination) and secondary failures (waning immunity seroconversion) is important for evaluation control programs developing countries. After a epidemic São Paulo, Brazil, 159 cases previously confirmed by detection specific immunoglobulin M (IgM) antibodies were tested IgG avidity, immune response,...
O Programa Nacional de Imunização, com mais três décadas existência, tem desempenhado papel fundamental no controle importantes doenças imunopreveníveis, atingindo atualmente altas taxas cobertura vacinal em praticamente todo território nacional. Esta situação instaura a necessidade se aprimorar as estratégias avaliação do programa, tanto na busca indicadores precisos, quanto mensuração e entendimento das desigualdades sociais relacionadas à vacinal. Entende-se que efetividade programa...
Despite the introduction of pneumococcal vaccine, Streptococcus pneumoniae remains a cause invasive diseases in Brazil. This study provides distribution serotypes and antimicrobial susceptibility patterns for isolates before during years COVID-19 pandemic two age groups, <5 ≥50 years. is national laboratory-based surveillance that uses data from Brazilian laboratory S. pre-COVID-19 (January 2016 to January 2020) (February 2020 May 2022) periods. Antimicrobial resistance was evaluated by...
A laboratory surveillance study was developed in Brazil 1993 to determine capsular types and antimicrobial susceptibility of Streptococcus pneumoniae strains. By studying 360 strains isolated from children with invasive infections three different cities, 8 out 34 were identified as being the most prevalent considered reference group for further analyses. This comprised 77.7% all studied, includes 1, 5, 6A/B, 9V, 14, 19F, 19A, 23F. The prevalence this significantly higher among pneumonia than...
OBJECTIVE: To compare the costs and benefits of pneumococcal conjugate vaccination compared with no from perspectives health care system society. METHODS: Using data established sources, we estimated incidence mortality due to invasive disease, pneumonia, acute otitis media (AOM) for a hypothetical birth cohort children 5 years. RESULTS: A universal program was capable annually avoiding 1 047 cases 58 226 209 862 AOM. When herd immunity effects were considered, prevented 1.3 million disease...
In 1992 a major vaccination strategy against measles-mumps-rubella was introduced in the State of Sāo, Brazil. This based on mathematical models and comprised pulse covering aII children aged 1–10 years, followed by inclusion this vaccine routine calendar at 15 months age. The present work reports evaluation efficacy mixed strategy. A rubella seroprevalence survey carried out immediately one year after campaign, comprising 4953 1–15 years. We show that average increased from 0.40 to 0.97...
Rubella vaccination is contraindicated during pregnancy. During mass immunization of women childbearing age against rubella, unknowingly pregnant may be vaccinated. To evaluate the effects rubella pregnancy, Brazilian state São Paulo conducted a follow-up study vaccinated campaign in 2001.Women pregnancy were reported to national surveillance system. In Paulo, included household interviews. Serum samples from tested for antirubella antibodies classify susceptibility infection. Children born...
This study analyzes the epidemiological behavior of meningococcal disease in city São Paulo, Brazil, over course 20th century. Applying data from patient records, death certificates, and surveillance, authors describe trends throughout century, seasonal variations, incidence distribution by area, age, gender. The temporal show constant during endemic periods, interrupted epidemic events. Four events last century occurred circumstances serious social disturbances were caused serogroups A (the...
OBJETIVO: Avaliar aspectos epidemiológicos, clínicos e terapêuticos de idosos com doenças cardiovasculares (DCV), no Brasil. MÉTODOS: Idosos DCV, atendidos em 36 serviços Cardiologia Geriatria do Brasil, foram investigados através questionário aplicado aos que tinham consulta marcada para o período analisado (um mês). RESULTADOS: Estudados 2196 65 a 96 anos, sendo 60% mulheres analisados os fatores risco: sedentarismo (74%), pressão arterial (PA) elevada (53%), LDL colesterol aumentado...
Resumo Com o processo de desinstitucionalização psiquiátrica, as famílias passaram a ser principais provedoras cuidados aos pacientes. Essa mudança marcou uma alteração no modo como família vinha participando do cuidado ao doente mental, mas dificuldades enfrentadas desempenho papel cuidador têm contribuído para transformações na sua vida. Esta pesquisa objetivou observar quais mudanças ocorrem nos âmbitos social, familiar e sexual cuidadores crianças adolescentes com transtornos mentais...
Meningococcal C conjugate (MenC) vaccine was introduced as part of the Brazilian National Immunisation Program in 2010 for children < 1 year age.The study objective to evaluate impact this vaccination strategy.An observational, mixed ecological and analytical conducted, based on time series panel data from surveillance records (2001-2013).A total 37,538 meningococcal disease cases were recorded during period. Of these, 19,997 attributed serogroup C. A decrease (MDC) incidence among aged...
Resurgent outbreaks of vaccine-preventable diseases that have previously been controlled or eliminated observed in many settings. Reactive vaccination campaigns may successfully control but must necessarily be implemented the face considerable uncertainty. Real-time surveillance provide critical information about at-risk population and optimal targets, itself limited by specificity disease confirmation. We propose an integrated modelling approach synthesizes historical demographic data with...
<b><i>Introduction:</i></b> Oculocutaneous albinism is an autosomal recessive disease caused by complete absence of or decrease in melanin biosynthesis melanocytes. Due to the reduction melanin, albinos are highly susceptible harmful effects ultraviolet radiation and at greater risk actinic damage skin cancer. There no epidemiological data on incidence Brazil. <b><i>Objective:</i></b> To analyze clinical profile patients with treated Pró-Albino...
OBEJETIVO: Analisar a representatividade da amostra e precisão das estimativas obtidas com o uso metodologia por conglomerados (30 7) proposta pela Organização Mundial Saúde mediante sua aplicação em inquéritos de cobertura vacinal realizados Diadema São Caetano do Sul, Estado Paulo, Brasil, 2000. MÉTODO:A amostras foi avaliada através comparação entre os setores censitários sorteados para demais nos dois municípios termos características sociodemográficas (estrutura etária população,...