A5100772072- Congenital heart defects research
- Photosynthetic Processes and Mechanisms
- Congenital Diaphragmatic Hernia Studies
- Polysaccharides and Plant Cell Walls
- Respiratory and Cough-Related Research
- Plant Stress Responses and Tolerance
- Plant Molecular Biology Research
- Natural Antidiabetic Agents Studies
- RNA modifications and cancer
- Mechanisms of cancer metastasis
- Pharmacological Effects of Medicinal Plants
- MicroRNA in disease regulation
- Microbial Community Ecology and Physiology
- Neural Networks and Applications
- Curcumin's Biomedical Applications
- Sugarcane Cultivation and Processing
- Pluripotent Stem Cells Research
- Plant responses to water stress
- Yersinia bacterium, plague, ectoparasites research
- Tannin, Tannase and Anticancer Activities
- MXene and MAX Phase Materials
- Plant-based Medicinal Research
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Renal and related cancers
Jiangxi University of Traditional Chinese Medicine
2013-2025
Shanghai University of Traditional Chinese Medicine
2022
XinHua Hospital
2020-2022
Shanghai Jiao Tong University
2020-2022
Nanjing Agricultural University
2022
Northeast Agricultural University
2018
Anhui Xinhua University
1990
Abstract Background Conotruncal defects (CTDs) are a type of heterogeneous congenital heart diseases (CHDs), but little is known about their etiology. Increasing evidence has demonstrated that fibroblast growth factor (FGF) 8 and FGF10 may be involved in the pathogenesis CTDs. Methods The variants FGF8 unrelated Chinese Han patients with CHDs (n = 585), healthy controls 319) were investigated. expression function these patient-identified detected to confirm potential pathogenicity...
ABSTRACT Background Brain imaging technologies can measure fluid intelligence (gF) levels more directly, objectively, and dynamically, compared to traditional questionnaire scales. To clarify the temporal mechanisms of graph theory in measuring gF, this study investigated relationship between theoretical indicators dorsolateral prefrontal cortex (DLPFC) gF under various time windows. Methods Using 30‐min resting‐state fNIRS (rs‐fNIRS) data Raven's Advanced Progressive Matrices from 116...
Soybean [Glycine max (L.) Merri.] is an important oilseed and food crop. In recent years, environmental degradation has accelerated soil alkalization, salinization, water deficit, which have seriously threatened the soybean quality yield. Chaperone DNAJ proteins play roles in plant response to a number of abiotic biotic stresses. Here, we investigated function gene, GmDNAJC7, tolerance GmDNAJC7 gene expression was induced by alkaline-salt, salt, drought treatments roots, suggesting its...
Purpose: To isolate and identify the cytotoxicity of constituents Sarcopyramis bodinieri var. delicate.Methods: S. delicate was extracted with hydrochloric acid-methanol fractionated ethyl acetate further. The chemical fraction were purified by a combination D101 macroporous resin Sephadex LH-20 column chromatography. structure characterized 1H-Nuclear Magnetic Resonance (NMR) electrospray ionization tandem mass spectrometry (ESI-MS). Apoptosis evaluated fluorescence staining Western blot...
Presently, over-the-counter drugs that can treat upper respiratory tract infections (URTI) are rarely effective and safe. Chaiqin Qingning Capsule (CQQNC), a Chinese patent medicine, which has been verified by long-term clinical practice is recommended experts for the treatment of URTI with fever. This study conducted prospective, double-blinded, randomized, multicenter controlled trial to evaluate effectiveness safety CQQNC in URTI.The was at 4 centers China. Eligible subjects were...
MicroRNAs play an important regulatory role in the proliferation and differentiation of skeletal muscle‐derived satellite cells (MDSCs). In particular, miR‐139 can inhibit tumor cell invasion, its expression is down‐regulated during C2C12 myoblast differentiation. The aim this study was thus to examine effect potential mechanism bovine MDSCs. found be significantly increased MDSC by stem‐loop reverse transcription‐polymerase chain reaction amplification. Statistical analysis myotube fusion...
Pulmonary atresia (PA) is a kind of congenital heart disease characterized by right ventricular outflow tract obstruction. It divided into PA with intact septum (PA/IVS) whose favorable form pulmonary valvular stenosis (PS), and septal defect (PA/VSD) tetralogy Fallot (TOF). Due to limitations in genetics etiology, whole-exome sequencing (WES) was utilized identify new variants associated the diseases.The data from PS-PA/IVS (n = 74), TOF-PA/VSD 100), 100 controls were obtained. The common...
Transcriptional regulation participates in heart development. However, the transcriptomes of human embryonic hearts during Carnegie stage (CS)10-CS16 have not been elucidated. Here, we found marked changes morphology and transcriptome from CS10 to CS11. At CS12-CS14, undergoes hypoxia-to-aerobic transformation. CS14-CS16, functions were related energy metabolism, cholesterol, processes inorganic substances. Moreover, cardiac progenitor cells derived stem (hESCs) most overlapped with those at...
Pulmonary atresia with ventricular septal defect (PA/VSD) is a rare congenital heart disease (CHD) characterized by lack of luminal continuity and blood flow from either the right ventricle or pulmonary artery, together VSDs. The prevalence PA/VSD about 0.2% live births approximately 2% CHDs. similar to tetralogy Fallot (TOF) in terms structural pathological characteristics. pathogenesis these two CHDs remains incompletely understood. It was previously reported that N‐myc...
Purpose: To isolate and identify chemical constituents with yeast α-glucosidase inhibitory activity from the methanol extract of V. myrtillus (blueberry) flowers.Methods: The active fraction (ethyl acetate extract) were chromatographed on C18 MPLC column, Sephadex LH-20 column semi-preparative HPLC column. isolated compounds identified by extensive 1H-nuclear magnetic resonance spectroscopy (NMR), 13C-NMR, 2D-NMR high resolution mass spectral (HR-MS) analyses.Results: Two phenolic compounds,...