Milton Rocha Moraes

ORCID: 0000-0003-4818-9650
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About
Contact & Profiles
Research Areas
  • Cardiovascular and exercise physiology
  • Heart Rate Variability and Autonomic Control
  • Sports Performance and Training
  • Muscle metabolism and nutrition
  • Exercise and Physiological Responses
  • Adipose Tissue and Metabolism
  • Dialysis and Renal Disease Management
  • Physical Education and Gymnastics
  • Healthcare Regulation
  • Blood Pressure and Hypertension Studies
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Nutrition and Health in Aging
  • Obesity, Physical Activity, Diet
  • Iron Metabolism and Disorders
  • Immune Cell Function and Interaction
  • Erythropoietin and Anemia Treatment
  • Parathyroid Disorders and Treatments
  • Genetics and Physical Performance
  • Adipokines, Inflammation, and Metabolic Diseases
  • Physical Education and Sports Studies
  • Apelin-related biomedical research
  • Telomeres, Telomerase, and Senescence
  • Thermoregulation and physiological responses
  • Congenital Heart Disease Studies
  • Martial Arts: Techniques, Psychology, and Education

Universidade Católica de Brasília
2014-2024

Universidade Federal de São Paulo
2004-2019

Universidade de Mogi das Cruzes
2007-2018

Fundação de Apoio à Universidade Federal de São Paulo
2009-2013

Zero to Three
2013

University Gama Filho
1982-2011

Universidade Federal de Minas Gerais
2007

Universidade de São Paulo
2007

The Kallikrein-Kinin System (KKS) has been implicated in several aspects of metabolism, including the regulation glucose homeostasis and adiposity. Kinins des-Arg-kinins are major effectors this system promote their effects by binding to two different receptors, kinin B2 B1 respectively. To understand influence KKS on pathophysiology obesity type 2 diabetes (T2DM), we generated an animal model deficient for both receptor genes leptin (obB1B2KO). Six-month-old obB1B2KO mice showed increased...

10.1371/journal.pone.0040573 article EN cc-by PLoS ONE 2012-07-19

Abstract Post-exercise hypotension is an important event for blood pressure regulation, especially in hypertensive individuals. Although post-exercise a well-known phenomenon, the mechanism responsible still unclear. The kallikrein-kinin system involved control, but its role has not yet been investigated. Thus, purpose of this study was to investigate involvement vasodilators bradykinin and des-Arg 9 -BK kallikrein activity promoted by 35 min cycle ergometer (CE) or circuit weight-training...

10.1515/bc.2007.055 article EN Biological Chemistry 2007-05-01

To investigate the antihypertensive effects of conventional resistance exercise (RE) on blood pressure (BP) hypertensive subjects, 15 middle-aged (46 ± 3 years) volunteers, deprived medication (reaching 153 6/93 2 mm Hg systolic/diastolic BP after a 6-week washout period) were submitted to 12-week RE training program (3 sets 12 repetitions at 60% 1 repetition maximum, times week nonconsecutive days). Blood was measured in all phases study (washout, training, detraining). Additionally, plasma...

10.1519/jsc.0b013e31822dfc5e article EN The Journal of Strength and Conditioning Research 2011-11-30

Background: Arterial hypertension is a serious health problem affecting mainly the elderly population. Recent studies have considered both aerobic and resistance exercises as non-pharmacological aid for arterial treatment. However, cardiovascular responses of to isometric exercise (eg, handgrip [IHG]) not yet been documented. Objective: The purpose this study was investigate different intensities exercise, well occurrence post-isometric hypotension in hypertensive people under...

10.2147/cia.s40560 article EN cc-by-nc Clinical Interventions in Aging 2013-06-01

Epidemiologic studies suggest that moderately intense training promotes augmented immune function, whereas strenuous exercise can cause immunosupression. Because the combat of cancer requires high high-intensity could negatively affect host organism; however, despite epidemiologic data, there is a lack experimental evidence to show harmful system. Therefore, we tested influence treadmill (10 weeks, 5 days/week, 30 mins/day, 85% VO 2 max) on system function and tumor development in Walker 256...

10.3181/0704-rm-93 article EN Experimental Biology and Medicine 2007-11-01

As the size of adipocytes increases during obesity, establishment resident immune cells in adipose tissue becomes an important source proinflammatory mediators. Exercise and caloric restriction are two important, nonpharmacological tools against body mass increase. To date, their effects on obese organisms, specifically when a high-fat diet is consumed, have been poorly investigated. Thus, after consuming diet, mice were submitted to chronic swimming training or 30% order investigate both...

10.1155/2013/395672 article EN cc-by Mediators of Inflammation 2013-01-01

Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown relationship between changes mass the cardiovascular system. However, this has not been fully elucidated. Methods. One hundred thirty community-dwelling Brazilian women (65.4 ± 6.3 years) were recruited to participate study. Data on body composition (via bioelectrical impedance measurements), parameters (using an automatic...

10.1155/2015/109824 article EN cc-by Journal of Aging Research 2015-01-01

This study aimed to verify the effect of 6 months periodized resistance training (RT) with and without blood flow restriction (BFR) in patients stage 2 chronic kidney disease (CKD) on glomerular filtration rate (GFR), uremic parameters, cytokines, klotho-fibroblast growth factor 23 (FGF23) axis.A total 105 subjects were randomized three groups 35 each: control (CTL), RT, RT + BFR. A first visit was required for an anamnesis evaluate number medications anthropometric measurements (body...

10.1249/mss.0000000000002465 article EN Medicine & Science in Sports & Exercise 2020-08-21

Abstract Patients in maintenance hemodialisys (HD) present sleep disorders, increased inflammation, unbalanced redox profiles, and elevated biomarkers representing endothelial dysfunction. Resistance training (RT) has shown to mitigate the loss of muscle mass, strength, improve inflammatory function while decreasing oxidative stress for those HD. However, relation between factors quality are inadequately described. The aim this study was verify effects 3 months RT on quality, balance, nitric...

10.1038/s41598-020-68602-1 article EN cc-by Scientific Reports 2020-07-16

Abstract Souza, LR, Vicente, JB, Melo, GR, Moraes, VC, Olher, RR, Sousa, IC, Peruchi, LH, Neves, RV, Rosa, TS, Ferreira, AP, and MR. Acute hypotension after moderate-intensity handgrip exercise in hypertensive elderly people. J Strength Cond Res 32(10): 2971–2977, 2018—Isometric (IHG) training is effective reducing blood pressure (BP), but little known about the occurrence of acute by postisometric (PIEH) underlying mechanisms. Ten sedentary people (7 women 3 men) individuals, with a mean...

10.1519/jsc.0000000000002460 article EN The Journal of Strength and Conditioning Research 2018-01-31

This study compared the effectiveness of dynamic resistance training (DRT) versus isometric RT (IRT) on osteogenesis and hormonal mechanisms involved in maintenance hemodialysis (MHD) patients. One hundred ninety-three MHD patients were randomized into three groups: control (CTL) (n = 60), DRT 66), IRT 67). A first visit was required for an anamnesis to evaluate number medications, biochemical, anthropometric measurements (dialysis adequacy, creatinine, urea, body mass, height, mass index)....

10.1152/japplphysiol.00416.2020 article EN Journal of Applied Physiology 2020-11-26

Studies have shown a positive influence of intense athletic training on several biomarkers aging, but it remains unclear whether this is dependent exercise-training-mode. This study compared redox balance, cytokine levels and aging between master sprinters endurance athletes, as well in young middle-aged individuals controls.Participants were male (SA, 50 ± 8.9yrs; n = 13) runners (EA, 53 8.2yrs; 18) with remarkable experience (~25yrs practice), besides untrained (YC, 22.7 3.9yrs; 17)...

10.1016/j.niox.2020.05.004 article EN publisher-specific-oa Nitric Oxide 2020-06-18

Resistance training (RT) has been recommended as a non-pharmacological treatment for moderate hypertension. In spite of the important role exercise intensity on prescription, there is still no data regarding effects RT severe hypertension (SH).This study examined two protocols (vertical ladder climbing), performed at different overloads maximal weight carried (MWC), blood pressure (BP) and muscle strength spontaneously hypertensive rats (SHR) with SH.Fifteen male SHR ENT#091;206 ± 10 mmHg...

10.5935/abc.20160019 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2016-03-01

The aim of this study was to examine the influence physical fitness on cardiac autonomic control in passengers prior to, during and following commercial flights. Twenty-two, physically active men (36.4 ± 6.4 years) undertook assessments followed by recordings 24-h heart rate (HR), variability (HRV), blood pressure (BP) a Control (no flight) Experimental (flight) day. Recordings were analyzed using two-way analysis variance for repeated measures with relationships between variables examined...

10.3389/fphys.2016.00648 article EN cc-by Frontiers in Physiology 2016-12-26

Abstract The Ironman is one of the most popular triathlon events in world. Such a race involves great number tactical decisions for healthy finish and best performance. Dehydration widely postulated to decrease performance known as cause dropouts Ironman. Despite importance hydration status after an triathlon, there clear lack review especially meta-analysis studies on this topic. Therefore, objective was systematically literature carry out investigating triathlon. We conducted systematic up...

10.2478/hukin-2018-0096 article EN Journal of Human Kinetics 2019-11-30
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