Hongwei Guo

ORCID: 0000-0003-4819-5874
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About
Contact & Profiles
Research Areas
  • Plant Molecular Biology Research
  • Plant Stress Responses and Tolerance
  • Plant Gene Expression Analysis
  • Photosynthetic Processes and Mechanisms
  • Postharvest Quality and Shelf Life Management
  • Plant Reproductive Biology
  • Light effects on plants
  • Plant Physiology and Cultivation Studies
  • Plant tissue culture and regeneration
  • Plant nutrient uptake and metabolism
  • Plant responses to water stress
  • Plant-Microbe Interactions and Immunity
  • Aortic Disease and Treatment Approaches
  • Cardiac Valve Diseases and Treatments
  • Insect-Plant Interactions and Control
  • Plant Micronutrient Interactions and Effects
  • Plant Virus Research Studies
  • Polysaccharides and Plant Cell Walls
  • Plant biochemistry and biosynthesis
  • Plant Parasitism and Resistance
  • Chromosomal and Genetic Variations
  • Greenhouse Technology and Climate Control
  • Aortic aneurysm repair treatments
  • Plant Pathogenic Bacteria Studies
  • Cardiac, Anesthesia and Surgical Outcomes

Southern University of Science and Technology
2017-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025

Peking University
2010-2024

Peking University People's Hospital
2024

First Automotive Works (China)
2022

82th Hospital of Pla
2021

Beijing Forestry University
2019-2021

AstraZeneca (Sweden)
2020

Center for Life Sciences
2011-2017

Hunan University
2012

The shift in plants from vegetative growth to floral development is regulated by red-far-red light receptors (phytochromes) and blue-ultraviolet A (cryptochromes). mutation the Arabidopsis thaliana CRY2 gene encoding a blue-light receptor apoprotein (CRY2) allelic late-flowering mutant, fha. Flowering cry2/fha mutant only incompletely responsive photoperiod. Cryptochrome 2 (cry2) positive regulator of flowering-time CO, expression which Analysis flowering cry2 phyB mutants response different...

10.1126/science.279.5355.1360 article EN Science 1998-02-27

Jasmonate (JA) and ethylene (ET) are two major plant hormones that synergistically regulate development tolerance to necrotrophic fungi. Both JA ET induce the expression of several pathogenesis-related genes, while blocking either signaling pathway abolishes induction these genes by alone or in combination. However, molecular basis JA/ET coaction interdependency is largely unknown. Here, we report Arabidopsis ET-stabilized transcription factors (EIN3 EIL1) integrate regulation gene...

10.1073/pnas.1103959108 article EN Proceedings of the National Academy of Sciences 2011-07-07

The phytohormone ethylene regulates multiple aspects of plant growth and development responses to environmental stress. However, the exact role in freezing stress remains unclear. Here, we report that negatively Arabidopsis thaliana. Freezing tolerance was decreased overproducer1 by application precursor 1-aminocyclopropane-1-carboxylic acid but increased addition biosynthesis inhibitor aminoethoxyvinyl glycine or perception antagonist Ag+. Furthermore, ethylene-insensitive mutants,...

10.1105/tpc.112.098640 article EN The Plant Cell 2012-06-01

Cryptochrome is a group of flavin-type blue light receptors that regulate plant growth and development. The function Arabidopsis cryptochrome 2 in the early photomorphogenesis seedlings was studied by using transgenic plants overexpressing CRY2 protein, cry2 mutant accumulating no protein. It found mediates light-dependent inhibition hypocotyl elongation stimulation cotyledon opening under low intensities light. In contrast to CRY1, expression rapidly down-regulated light-intensity dependent...

10.1073/pnas.95.5.2686 article EN Proceedings of the National Academy of Sciences 1998-03-03

Abstract Plant responses to ethylene are mediated by regulation of EBF1/2-dependent degradation the ETHYLENE INSENSITIVE3 (EIN3) transcription factor. Here, we report that level EIL1 protein is upregulated through an pathway. Genetic analysis revealed and EIN3 cooperatively but differentially regulate a wide array responses, with mainly inhibiting leaf expansion stem elongation in adult plants largely regulating multitude seedlings. When EBF1 EBF2 disrupted, constitutively accumulate nucleus...

10.1105/tpc.110.076588 article EN The Plant Cell 2010-07-01

Abstract The interactions between phytohormones are crucial for plants to adapt complex environmental changes. One example is the ethylene-regulated local auxin biosynthesis in roots, which partly contributes ethylene-directed root development and gravitropism. Using a chemical biology approach, we identified small molecule, l-kynurenine (Kyn), effectively inhibited ethylene responses Arabidopsis thaliana tissues. Kyn application repressed nuclear accumulation of ETHYLENE INSENSITIVE3 (EIN3)...

10.1105/tpc.111.089029 article EN The Plant Cell 2011-11-01

Abstract Numerous endogenous and environmental signals regulate the intricate highly orchestrated process of plant senescence. Ethylene is a well-known inducer senescence, including fruit ripening flower leaf However, underlying molecular mechanism ethylene-induced senescence remains to be elucidated. Here, we examine ETHYLENE-INSENSITIVE3 (EIN3), key transcription factor in ethylene signaling, find that EIN3 functional senescence-associated gene. Constitutive overexpression or temporary...

10.1105/tpc.113.113340 article EN The Plant Cell 2013-09-01

The effects of auxins on plant growth and development have been known for more than 100 years, yet our understanding how plants synthesize this essential hormone is still fragmentary at best. Gene loss- gain-of-function studies conclusively implicated three gene families, CYTOCHROME P450 79B2/B3 (CYP79B2/B3), YUCCA (YUC), TRYPTOPHAN AMINOTRANSFERASE OF ARABIDOPSIS1/TRYPTOPHAN AMINOTRANSFERASE-RELATED (TAA1/TAR), in the production reference Arabidopsis thaliana. Each these families believed...

10.1105/tpc.111.088047 article EN The Plant Cell 2011-11-01

Leaf senescence is a highly coordinated, complicated process involving the integration of numerous internal and environmental signals. Salicylic acid (SA) reactive oxygen species (ROS) are two well-defined inducers leaf whose contents progressively interdependently increase during via an unknown mechanism. Here, we characterized transcription factor WRKY75 as positive regulator in Arabidopsis thaliana. Knockdown or knockout delayed age-dependent senescence, while overexpression accelerated...

10.1105/tpc.17.00438 article EN The Plant Cell 2017-10-23

Abstract Pathogen/microbe-associated molecular patterns (PAMPs/MAMPs) trigger plant immunity that forms the first line inducible defenses in plants. The regulatory mechanism of MAMP-triggered immunity, however, is poorly understood. Here, we show Arabidopsis thaliana transcription factors ETHYLENE INSENSITIVE3 (EIN3) and INSENSITIVE3-LIKE1 (EIL1), previously known to mediate ethylene signaling, also negatively regulate PAMP-triggered immunity. Plants lacking EIN3 EIL1 display enhanced PAMP...

10.1105/tpc.108.065193 article EN cc-by The Plant Cell 2009-08-01

Ethylene has been regarded as a stress hormone to regulate myriad responses. Salinity is one of the most serious abiotic stresses limiting plant growth and development. But how ethylene signaling involved in response salt poorly understood. Here we showed that Arabidopsis plants pretreated with exhibited enhanced tolerance stress. Gain- loss-of-function studies demonstrated EIN3 (ETHYLENE INSENSITIVE 3) EIL1 (EIN3-LIKE 1), two ethylene-activated transcription factors, are necessary...

10.1371/journal.pgen.1004664 article EN cc-by PLoS Genetics 2014-10-16

Plants have evolved sophisticated systems for adaptation to their natural habitat. In response developmental and environmental cues, plants produce perceive jasmonate (JA) signals, which induce degradation of JASMONATE-ZIM-Domain (JAZ) proteins derepress the JAZ-repressed transcription factors regulate diverse aspects defense responses processes. Here, we identified bHLH subgroup IIId (bHLH3, bHLH13, bHLH14 bHLH17) as novel targets JAZs. These act repressors function redundantly negatively...

10.1371/journal.pgen.1003653 article EN cc-by PLoS Genetics 2013-07-25

Significance PHYTOCHROME-INTERACTING FACTORS (PIFs) are central integrators of plants’ responses to various environmental signals. In this study, we show that PIF3 acts as a negative regulator plant cold acclimation by directly repressing the expression CBF genes, whereas its protein stability is negatively regulated two F-box proteins, EBF1 and EBF2, via 26S proteasome pathway. Moreover, EBF2 degraded under stress, which enhances protein. Collectively, our study establishes an important...

10.1073/pnas.1706226114 article EN Proceedings of the National Academy of Sciences 2017-07-24

Abstract The apical hook is an essential structure that enables epigeal plants to protrude through the soil. Arabidopsis thaliana HOOKLESS1 (HLS1) reported be a key regulator of development and direct target gene ethylene (ET)-activated transcription factors ETHYLENE INSENSITIVE3 (EIN3) its close homolog EIN3-Like1. Previous research has shown phytohormones jasmonate (JA) ET antagonistically regulate development, although underlying molecular mechanism largely unknown. Here, we report JA...

10.1105/tpc.113.122002 article EN The Plant Cell 2014-03-01

Abstract During leaf senescence, the final stage of development, nutrients are recycled from leaves to other organs, and therefore proper control senescence is thus critical for plant fitness. Although substantial progress has been achieved in understanding annual plants, molecular factors that perennial woody plants largely unknown. Using RNA sequencing, we obtained a high-resolution temporal profile gene expression during autumn poplar (Populus tomentosa). Identification hub transcription...

10.1093/plcell/koab046 article EN cc-by-nc-nd The Plant Cell 2021-02-04

ABSTRACT The Arabidopsis photoreceptors cry1, cry2 and phyB are known to play roles in the regulation of flowering time, for which molecular mechanisms remain unclear. We have previously hypothesized that mediates a red-light inhibition floral initiation blue-light function. Studies cry2/phyB double mutant provide direct evidence support this hypothesis. function cryptochromes induction was further investigated using cry2/cry1 mutants. mutants showed delayed monochromatic blue light, whereas...

10.1242/dev.126.10.2073 article EN Development 1999-05-15

The ability to switch from skotomorphogenesis photomorphogenesis is essential for seedling development and plant survival. Recent studies revealed that COP1 phytochrome-interacting factors (PIFs) are key regulators of this transition by repressing the photomorphogenic responses and/or maintaining skotomorphogenic state etiolated seedlings. Here we report hormone ethylene plays a crucial role in facilitating greening seedlings upon light irradiation. Activation EIN3/EIL1 both necessary...

10.1073/pnas.0907670106 article EN Proceedings of the National Academy of Sciences 2009-12-01
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