- Photonic and Optical Devices
- Advanced Fiber Laser Technologies
- Advanced Fiber Optic Sensors
- Semiconductor Lasers and Optical Devices
- Metamaterials and Metasurfaces Applications
- Photonic Crystals and Applications
- Plasmonic and Surface Plasmon Research
- Laser-Matter Interactions and Applications
- Retinal Diseases and Treatments
- Visual perception and processing mechanisms
- Surgical Sutures and Adhesives
- Advanced Antenna and Metasurface Technologies
- Ophthalmology and Visual Impairment Studies
- Intramuscular injections and effects
- Orbital Angular Momentum in Optics
- Gold and Silver Nanoparticles Synthesis and Applications
- Intraocular Surgery and Lenses
- Mass Spectrometry Techniques and Applications
- Connective Tissue Growth Factor Research
- Advanced Fluorescence Microscopy Techniques
- Skin Protection and Aging
- Nonlinear Optical Materials Studies
- Corneal surgery and disorders
- Laser Material Processing Techniques
- Connexins and lens biology
Ludwig-Maximilians-Universität München
2008-2025
Nanosystems Initiative Munich
2020-2025
Center for NanoScience
2023
Max Planck Institute of Quantum Optics
2022
Kansas State University
2019
Women's General Hospital
2008
Abstract The realization of lossless metasurfaces with true chirality crucially requires the fabrication three-dimensional structures, constraining experimental feasibility and hampering practical implementations. Even though assembly metallic nanostructures has been demonstrated previously, resulting plasmonic resonances suffer from high intrinsic radiative losses. concept photonic bound states in continuum (BICs) is instrumental for tailoring losses diverse geometries, especially when...
Due to their broken symmetry, chiral plasmonic nanostructures have unique optical properties and numerous applications. However, there is still a lack of comprehension regarding how chirality transfer occurs between circularly polarized light (CPL) these structures. Here, we thoroughly investigate the plasmon-assisted growth nanoparticles from achiral Au nanocubes (AuNCs) via CPL without involvement any molecule stimulators. We identify structural our synthesized using circular differential...
<h3>Purpose:</h3> To evaluate the effect of intravitreal bevacizumab (Avastin) injections on visual acuity (VA) and foveal retinal thickness in patients with macular oedema secondary to branch vein occlusion. <h3>Methods:</h3> A prospective, non-comparative, consecutive, interventional case series 34 patients. Patients received repeated 1.25 mg bevacizumab. Main outcome measures were VA (Snellen charts ETDRS) (optical coherence tomography measurements) a follow-up period 6 months....
Light-field driven charge motion links semiconductor technology to electric fields with attosecond temporal control. Motivated by ultimate-speed electron-based signal processing, strong-field excitation has been identified viable for the ultrafast manipulation of a solid's electronic properties but found evoke perplexing post-excitation dynamics. Here, we report on single-photon-populating conduction band wide-gap dielectric within approximately one femtosecond. We control subsequent Bloch...
Abstract Due to their broken symmetry, chiral plasmonic nanostructures have unique optical properties and numerous applications. However, there is still a lack of comprehension regarding how chirality transfer occurs between circularly polarized light (CPL) these structures. Here, we thoroughly investigate the plasmon‐assisted growth nanoparticles from achiral Au nanocubes (AuNCs) via CPL without involvement any molecule stimulators. We identify structural our synthesized using circular...
Conformational isomerism plays a crucial role in defining the physical and chemical properties biological activity of molecules ranging from simple organic compounds to complex biopolymers. However, it is often significant challenge differentiate separate these isomers experimentally as they can easily interconvert due their low rotational energy barrier. Here, we use momentum correlation fragment ions produced after inner-shell photoionization distinguish conformational 1,2-dibromoethane...
The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured RPE cells were exposed 2, 4, 8, 12% CSE concentration for 24 hours. Cell loss detected by viability assay. Lipid peroxidation assessed cis-parinaric acid (PNA) fluorescence. Senescence-associated ß-galactosidase (SA-ß-Gal) activity...
Due to their unique capabilities, hollow-core waveguides are playing an increasingly important role, especially in meeting the growing demand for integrated and low-cost photonic devices sensors. Here, we present antiresonant microgap waveguide as a platform on-chip investigation of light-gas interaction over centimeter-long distances. The design consists segments separated by gaps that allow external access core region, while samples with lengths up 5 cm were realized on silicon chips...
Off-axis twisted waveguides possess unique optical properties such as circular and orbital angular momentum (OAM) birefringence, setting them apart from their straight counterparts. Analyzing mode formation in helical relies on the use of specific coordinate frames that follow twist structure. In this paper, differences between modes forming high-contrast off-axis defined three most important systems---the Frenet-Serret, helicoidal, or Overfelt frame---are investigated through numerical...
Emerging applications in spectroscopy-related bioanalytics demand for integrated devices with small geometric footprints and fast response times. While hollow core waveguides principally provide such conditions, currently used approaches include limitations as long diffusion times, limited light–matter interaction, substantial implementation efforts, difficult waveguide interfacing. Here, we introduce the concept of optofluidic light cage that allows reliable spectroscopy using a novel...
Purpose To evaluate the efficacy of a laser photolysis (LP) system in preventing posterior capsule opacification (PCO) human ex vivo PCO model. Setting Ars Ophthalmica Study Center, Department Ophthalmology, General Hospital Linz, Medical Faculty Johannes Kepler University, Austria, and Ludwig-Maximillians-University, Munich, Germany. Design Prospective randomized controlled laboratory trial. Methods Open sky extracapsular cataract extraction following implantation capsular tension ring...
Three-dimensional laser nanoprinting represents a unique approach for implementing on-chip hollow-core waveguides. Here we discuss the fabrication characteristics of light cage geometry arising from used two-photon polymerization lithography. We reveal current limits achievable waveguide length (3 cm), single strand aspect ratio (8200) and modal attenuation. Very high reproducibility cages on same chip is found, while different conditions in cycles impose chip-to-chip variations. also...
Twisted optical fibers are a promising platform for manipulating circularly polarized light and orbital angular momentum beams applications such as nonlinear frequency conversion, communication, or chiral sensing. However, integration into chip-scale technology is challenging because twisted incompatible with planar photonics the achieved twist rates limited. Here, we address these challenges by introducing concept of 3D-nanoprinted on-chip hollow-core cages. We show theoretically...
Interfacing integrated on-chip waveguides with spectroscopic approaches represents one research direction within current photonics aiming at reducing geometric footprints and increasing device densities. Particularly relevant is to connect chip-integrated established fiber-based circuitry, opening up the possibility for a new class of devices field photonics. Here, attractive waveguide light cage, confining guiding in low-index core through anti-resonance effect. This waveguide, implemented...
Nanoparticle tracking analysis (NTA) is a widely used methodology to investigate nanoscale systems at the single species level. Here, we introduce locally structured on-chip optofluidic hollow-core light cage, as novel platform for waveguide-assisted NTA. This hollow waveguide guides by antiresonant effect in sparse array of dielectric strands and includes local modification realize aberration-free individual nano-objects, defining solution with properties specifically tailored The key...
Here, we unlock the properties of recently introduced on-chip hollow-core microgap waveguide in context optofluidics which allows for intense light-water interaction over long lengths with fast response times. The nanoprinted operates by anti-resonance effect visible and near-infrared domain includes a hollow core defined gaps every 176 µm. spectroscopic capabilities are demonstrated various absorption-related experiments, showing that Beer-Lambert law can be applied without any...
The on-chip detection of fluorescent light is essential for many bioanalytical and life-science related applications. Here, the optofluidic cage consisting a sparse array micrometer encircling hollow core represents an innovative concept, particularly waveguide-based spectroscopy. In present work, we demonstrate potential concept in context integrated fluorescence Specifically, show that from dye-doped aqueous solution generated nanoprinted dual-ring can be efficiently captured guided to...
PURPOSE: To evaluate a capsular tension ring (CTR)–supported anterior and posterior capsule opacification (PCO) model in cadaver eyes. The effect of CTR designs on lens shape epithelial cell (LEC) growth were investigated vitro. SETTING: Department Ophthalmology, Ludwig-Maximilians-University, Munich, Germany. METHODS: Following open-sky extracapsular cataract extraction, models implanted 32 eyes 16 human donors. expansion by the CTRs was evaluated. bags supported excised maintained at...
The realization of lossless metasurfaces with true chirality crucially requires the fabrication three-dimensional structures, constraining their feasibility for experiments and hampering practical implementations. Even though assembly metallic nanostructures has been demonstrated previously, resulting plasmonic resonances suffer from high intrinsic radiative losses. concept photonic bound states in continuum (BICs) is instrumental tailoring losses diverse geometries, especially when...
Hollow-core waveguides represent a promising type of on-chip waveguide, enabling strong light-matter interactions for guiding light directly in the medium interest. are very established fiber optics, while they receive much less attention photonics. Here, we will show how 3D nanoprinting is used to transfer hollow-core waveguide concepts from optics Two main types nanoprinted discussed, yielding high-power fraction core and lateral access region. We explain applications these gas-...
Off-axis twisted waveguides possess unique optical properties such as circular and orbital angular momentum (OAM) birefringence, setting them apart from their straight counterparts. Analyzing mode formation in helical relies on the use of specific coordinate frames that follow twist structure, making waveguide invariant along one new coordinates. In this study, differences between modes forming high-contrast off-axis defined three most important systems - Frenet-Serret, helicoidal, or...