A5020030470- Pregnancy and preeclampsia studies
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Health Systems, Economic Evaluations, Quality of Life
- Cancer Risks and Factors
- Maternal and fetal healthcare
- Coronary Interventions and Diagnostics
- Maternal and Perinatal Health Interventions
- Pregnancy-related medical research
- Peripheral Artery Disease Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Bariatric Surgery and Outcomes
- Healthcare Systems and Practices
- Cardiac Health and Mental Health
- Immune Cell Function and Interaction
- Neonatal Respiratory Health Research
- Cardiac Imaging and Diagnostics
- Blood groups and transfusion
- Global Maternal and Child Health
- Acute Myocardial Infarction Research
- Cytomegalovirus and herpesvirus research
- Hematopoietic Stem Cell Transplantation
- Cardiovascular Issues in Pregnancy
- Emergency and Acute Care Studies
- Neutropenia and Cancer Infections
Stanford University
2006-2024
Stanford Medicine
2024
Cedars-Sinai Medical Center
2017
Stanford Health Care
2013-2016
University of California, Irvine Medical Center
2015
California Pacific Medical Center
2012
Pacific Business Group on Health
2012
Northwestern University
2010
University of Pittsburgh
2004-2010
University of Cincinnati
2010
To identify nutrients, foods, and dietary patterns associated with stress fracture risk changes in bone density among young female distance runners.Two-year, prospective cohort study. Observational data were collected the course of a multicenter randomized trial effect oral contraceptives on health.One hundred twenty-five competitive runners ages 18-26 years.Dietary variables assessed food frequency questionnaire.Bone mineral content (BMD/BMC) spine, hip, total body measured annually by dual...
Findings from studies examining risk of preterm birth associated with elevated prepregnancy body mass index (BMI) have been inconsistent.Within a large population-based cohort, we explored associations between BMI and spontaneous across spectrum BMI, gestational age, racial/ethnic categories. We analysed data for 989,687 singleton births in California, 2007-09. Preterm was grouped as 20-23, 24-27, 28-31, or 32-36 weeks gestation (compared 37-41 weeks). categorised <18.5 (underweight);...
Cesarean delivery rates in California and the United States rose by 50% between 1998 2008 vary widely among states, regions, hospitals, health care providers. The leading driver of both rise variation is first-birth cesarean deliveries performed during labor. With large increase primary deliveries, repeat now has emerged as largest single indication. economic costs, risks, negligible benefits for most mothers newborns these higher point to urgent need a new approach working with women This...
Background— Coronary bypass surgery (CABG) and angioplasty (PTCA) have been compared in several randomized trials, but data about long-term economic quality-of-life outcomes are limited. Methods Results— Cost were collected prospectively from 934 patients who the Bypass Angioplasty Revascularization Investigation (BARI) followed up for 10 to12 years. CABG had 53% higher costs initially, gap closed to <5% during first 2 years; after 12 years, mean cumulative cost of was $123 000 versus...
The economic outcomes of clinical management strategies are important in assessing their value to patients.Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) randomized patients with type diabetes mellitus and angiographically documented, stable coronary disease (1) prompt revascularization versus medical therapy delayed as needed relieve symptoms (2) insulin sensitization provision. Before randomization, the physician declared whether artery bypass grafting or...
Background— Health status is a key outcome for comparing treatments, particularly when mortality does not differ significantly. Methods and Results— Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) randomized 2368 patients with type diabetes mellitus stable ischemic heart disease to (1) prompt revascularization versus medical therapy (2) insulin sensitization provision. Randomization was stratified by the intended method of revascularization, coronary artery bypass...
Objective: To evaluate the association between pre-pregnancy body mass index (BMI) and adverse pregnancy outcomes using a large administrative database. Methods: Retrospective cohort study of California women delivering singletons in 2007. The BMI category were evaluated multivariate logistic regression. Results: Among 436,414 women, increasing was associated with odds outcomes. Obese (BMI = 30–39.9) nearly 3x more likely to have gestational diabetes (OR 2.83, 95% CI 2.74–2.92)...
In Brief OBJECTIVE: To examine the association of antenatal weight gain above and below 2009 Institute Medicine (IOM) guidelines in super-obese population (body mass index [BMI] 50 or higher) on maternal neonatal morbidities gestational hypertension preeclampsia (pregnancy-induced hypertension), diabetes mellitus, cesarean delivery, birth more than 4,000 g 4,500 g, low weight, preterm birth. METHODS: The effect was assessed this retrospective cohort study using California certificate patient...
To examine the impact of change in body mass index (BMI) during pregnancy on incidence macrosomia.This is a retrospective cohort study using 2007 linked birth certificate and discharge diagnosis data from state California. Adjusted odds ratios (aOR) with 95% confidence intervals (CI) were calculated for outcome macrosomia, as function categorical BMI: BMI loss (<-0.5), no (-0.5 to 0.5), minimal (0.6 5), moderate (5.1 10), excessive (>10). The was determined entire then stratified by...
To examine the impact of pregnancy changes in body mass index (BMI) on incidence cesarean delivery.This is a retrospective cohort study using linked birth certificate and discharge diagnosis data from year 2007. Adjusted odds ratios (aOR) were calculated for outcome delivery, as function categorical change BMI (kg/m(2)): loss (BMI change<-0.5), no (-0.5 to 0.5), minimal (0.6 5), moderate (5.1 10) excessive (>10). The was determined entire then stratified by prepregnancy category.The...
<b>Objective</b> The objective of this study was to assess utilization specialist coverage and checklists in perinatal settings examine by birth asphyxia rates. <b>Design</b> This is a survey California maternity hospitals concerning checklist use prepare for delivery room resuscitation 24-hour in-house (pediatrician/neonatologist, obstetrician, obstetric anesthesiologist) results linked hospital rates (preterm low weight births were excluded). <b>Results</b> Of 253 hospitals, 138 responded...
(R,R′)-4′-Methoxy-1-naphthylfenoterol (MNF) promotes growth inhibition and apoptosis of human HepG2 hepatocarcinoma cells via cannabinoid receptor (CBR) activation. The synthetic CB1R inverse agonist, AM251, has been shown to block the anti-mitogenic effect MNF in these cells; however, AM251 is also an agonist recently deorphanized, lipid-sensing receptor, GPR55, whose upregulation contributes carcinogenesis. Here, we investigated role GPR55 signaling PANC-1 cancer cell lines culture by...
In observational studies, clinical outcomes for black patients with coronary disease have been worse than white patients. There are few data from randomized trials comparing the of revascularization between and patients.We analyzed Bypass Angioplasty Revascularization Investigation trial. At study entry, 113 had significantly higher rates diabetes, hypertension, smoking, heart failure, abnormal left ventricular function 1653 Black mortality (hazard ratio, 2.16; P<0.001), which remained...