A5037956991- Malaria Research and Control
- Mosquito-borne diseases and control
- SARS-CoV-2 and COVID-19 Research
- Travel-related health issues
- Influenza Virus Research Studies
- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Viral Infections and Vectors
- Mobile Health and mHealth Applications
- Tuberculosis Research and Epidemiology
- Parasites and Host Interactions
- Global Maternal and Child Health
- Traffic and Road Safety
- Bird parasitology and diseases
- Pneumonia and Respiratory Infections
- ICT in Developing Communities
- Data-Driven Disease Surveillance
- Hepatitis Viruses Studies and Epidemiology
- Dengue and Mosquito Control Research
- Vector-borne infectious diseases
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis B Virus Studies
- Zoonotic diseases and public health
- Diagnosis and treatment of tuberculosis
- COVID-19 Clinical Research Studies
Mahidol University
2016-2025
Mahidol Oxford Tropical Medicine Research Unit
2015-2024
Biophics
2023-2024
Ministry of Public Health
2015-2022
University of Bremen
2022
Department of Disease Control
2015
Japan Anti Tuberculosis Association
2013
University of Maryland, Baltimore
2006-2010
Malaria still remains a public health problem in some districts of Bhutan despite marked reduction cases last few years. To strengthen the country's prevention and control measures, this study was carried out to develop forecasting prediction models malaria incidence endemic using time series ARIMAX.This retrospectively monthly reported from centres Vector-borne Disease Control Programme (VDCP) meteorological data Meteorological Unit, Department Energy, Ministry Economic Affairs. Time...
Production of affordable coronavirus disease 2019 (COVID-19) vaccines in low- and middle-income countries is needed. NDV-HXP-S an inactivated egg-based recombinant Newcastle virus vaccine expressing the spike (S) protein severe acute respiratory syndrome 2 (SARS-CoV-2). It's being developed by public sector manufacturers Thailand, Vietnam, Brazil; herein are initial results from Thailand.This phase 1 stage a randomised, dose-escalation, observer-blind, placebo-controlled, 1/2 trial was...
ABSTRACT Chloroquine combined with primaquine has been the standard radical curative regimen for Plasmodium vivax and ovale malaria over half a century. In an open-label crossover pharmacokinetic study, 16 healthy volunteers (4 males 12 females) aged 20 to 47 years were randomized into two groups of three sequential hospital admissions receive single oral dose 30 mg (base) primaquine, 600 chloroquine, drugs together. The coadministration did not affect chloroquine or desethylchloroquine...
Production of affordable coronavirus disease 2019 (COVID-19) vaccines in low- and middle-income countries is needed. NDV-HXP-S an inactivated egg-based Newcastle virus (NDV) vaccine expressing the spike protein severe acute respiratory syndrome 2 (SARS-CoV-2) Wuhan-Hu-1. The was stabilized incorporated into NDV virions by removing polybasic furin cleavage site, introducing transmembrane domain cytoplasmic tail fusion NDV, six prolines for stabilization prefusion state. Vaccine production...
Abstract Background Plasmodium vivax has a dormant hepatic stage, called the hypnozoite, which can cause relapse months after initial attack. For 50 years, primaquine been used as hypnozoitocide to radically cure P. infection, but major concerns remain regarding side-effects of drug and adherence 14-day regimen. This study examined effectiveness using directly-observed therapy (DOT) method for radical treatment malaria prevent reappearance parasite within 90-day follow-up period. Other...
Village malaria workers (VMWs) and mobile (MMWs) are a critical component of Cambodia's national strategy to eliminate Plasmodium falciparum by 2025. Since 2004, VMWs have been providing diagnosis through the use rapid diagnostic tests free-of-charge artemisinin-based combination therapy in villages more than 5 km away from closest health facility. They also played key role delivery behaviour change communication interventions this target population. This study aimed assess job performance...
Acute undifferentiated febrile illness (AUFI) has been a diagnostic dilemma in the tropics. Without accurate point-of-care tests, information on local pathogens and clinical parameters is essential for presumptive diagnosis. A prospective hospital-based study was conducted at Bangkok Hospital Tropical Diseases from 2013 to 2015 determine common etiologies of AUFI. total 397 adult AUFI cases, excluding malaria by blood smear, were enrolled. Rapid tests tropical infections performed admission,...
With the goal for malaria elimination in Thailand set 2024, increased coverage and utilization of bed net, especially insecticide-treated net (ITN) or long-lasting insecticidal (LLIN) is a key strategy. This study aims to provide necessary information about ownership among population at risk living along Thai-Myanmar border Tak province.A cross-sectional was conducted using mixed-method approach 331 households from 5 hamlets villages border. The research tools included questionnaire,...
Dengue infection has been a public health problem worldwide, especially in tropical areas. A lack of sensitive diagnostic methods the early phase illness is one challenging problems clinical practices. We, herein, analyzed 86 sera acute febrile patients, from both dengue and non-dengue illness, to study performance diagnostics. When compared with detection by Polymerase Chain Reaction (PCR), NS1 enzyme-linked immunosorbent assay (ELISA) had highest sensitivity 82.4% (with 94.3% specificity),...
Differentiating dengue patients from other acute febrile illness is a great challenge among physicians. Several diagnosis methods are recommended by WHO. The application of specific laboratory tests still limited due to high cost, lack equipment, and uncertain validity. Therefore, clinical remains common practice especially in resource settings. Bayesian networks have been shown be useful tool for diagnostic decision support. This study aimed construct network models using basic demographic,...
Cross-border disease transmission is a key challenge for prevention and control of outbreaks. Variation in surveillance structure national guidelines used different countries can affect their data quality the timeliness outbreak reports. This study aimed to evaluate reporting four Mekong Basin Disease Surveillance network (MBDS). Data on outbreaks occurring from 2010 2015 were obtained reports Cambodia, Lao PDR, Myanmar, Vietnam. included total cases, geographical information, dates at...
In low malaria transmission areas, many people acquire multiple infections within a single season. This study aimed to describe the pattern and epidemiological profile of recurrence in hypoendemic area western Thailand identify factors associated with having episodes.An open cohort 7000 residents seven clusters along Thai-Myanmar border was followed during 6.5-year period (2011-mid 2017). Symptomatic asymptomatic were detected by passive case detection (PCD), weekly household visit, mass...
The study aimed to compare the immunogenicity and safety of fractional (half) third doses heterologous COVID-19 vaccines (AZD1222 or BNT162b2) full after two-dose CoronaVac when boosting three different extended intervals.
Dengue is one of the health problems in Myanmar. Thus, promotion schools considered a key approach for reducing risk-taking behaviours related to dengue.The study aimed evaluate dengue training programme high school students measure changes knowledge, attitude and practices (KAP) towards dengue; effectiveness improving prevention control among families determining larval indices their dwelling places.The was conducted Grades 9 10 Yangon. In total, 300 intervention received were compared with...
Speeding tickets are the most commonly used tool to deter speeders, yet little is known about how speeding citations affect individual drivers' behavior over time. This study examined effects of being cited for and types legal consequences on subsequent citations, which an indicator behavior.A cohort 3,739,951 Maryland licensed drivers were identified followed one year. Drivers categorized by whether or not they received a citation in May 2002. Among those 2002, grouped type penalty (fines...
Effective malaria control has successfully reduced the burden in many countries, but to eliminate malaria, these countries will need further improve their efforts. Here, a programme was critically evaluated very low-endemicity Thai-Myanmar border population, where early detection and prompt treatment have substantially reduced, though not ended, Plasmodium falciparum transmission, part due carriage of late-maturing gametocytes that remain post-treatment. To counter this effect, WHO...
Background Each year millions of travelers visit Southeast Asia where rabies is still prevalent. This study aimed to assess the risk exposure, i.e., by being bitten or licked an animal, among in Asia. The secondary objective was their attitudes and practices related rabies. Methodology/Principal Findings Foreign departing destination outside were invited fill out questionnaire departure hall Bangkok International Airport. They asked about demographic profile, travel characteristics,...
At the verge of elimination malaria in Bhutan, this study was carried out to analyse trend endemic districts Bhutan and identify clusters at sub-districts. The findings would aid implementing control activities. Poisson regression performed incidences district level from 1994 2008. Spatial Empirical Bayesian smoothing deployed sub-district 2004 Trend overall most have decreased except Pemagatshel, which has an increase trend. cluster-outlier analysis showed that were mostly concentrated...
Background Thailand is among the top five countries with effective COVID-19 transmission control. This study examines how news of presence in Thailand, as well varying levels government restriction on movement, affected human mobility a rural Thai population along border Myanmar. Methods makes use data collected using smartphone app. Between November 2019 and June 2020, four major events concerning information dissemination or intervention give rise to time intervals analysis. Radius...
<sec> <title>BACKGROUND</title> Protecting personal health information (PHI) has long been a key ethical concern in healthcare, but with the rise of eHealth systems, privacy concerns have intensified. In least developed countries (LDCs) like Myanmar, where digital literacy is low, public and governmental awareness issues limited, data protection laws are lacking, PHI challenges remain largely unaddressed understudied. </sec> <title>OBJECTIVE</title> This study aimed to assess extent related...
The rising prevalence of Plasmodium vivax ( P. ) malaria challenges elimination efforts, particularly in the Greater Mekong Subregion, although adherence to required 14-day primaquine (PQ) regimen remains a major obstacle. This study evaluated effectiveness family-administered, directly observed treatment intervention improving PQ among patients with confirmed from October 2022 March 2023. A cluster-randomized controlled trial was conducted five villages and control Kachin State, Myanmar....
The area along the Thai-Cambodian border is considered an epicenter of anti-malarial drug resistance. Recently, parasite resistance to artemisinin-based therapies has been reported in area. artemisinin containment project was initiated November 2008, with aim limit resistant parasites and eliminate malaria this region. This study describes response therapy among falciparum patients area, using data from surveillance programmed under project.The conducted seven provinces Thailand border. Data...