A5019706094- Rabies epidemiology and control
- Virology and Viral Diseases
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Poxvirus research and outbreaks
- Malaria Research and Control
- Influenza Virus Research Studies
- Microbial infections and disease research
- Vaccine Coverage and Hesitancy
- Travel-related health issues
- Pneumonia and Respiratory Infections
- Vibrio bacteria research studies
- Viral Infections and Outbreaks Research
- Respiratory viral infections research
- Bacterial Infections and Vaccines
- Streptococcal Infections and Treatments
- Antibiotic Use and Resistance
- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- Antifungal resistance and susceptibility
- Yersinia bacterium, plague, ectoparasites research
- Leptospirosis research and findings
- Fungal Infections and Studies
- Nosocomial Infections in ICU
- Bacillus and Francisella bacterial research
Chulalongkorn University
2014-2025
Queen Saovabha Memorial Institute
2009-2024
Thai Red Cross Society
2009-2024
King Chulalongkorn Memorial Hospital
2000-2023
Office of Infectious Diseases
2022
Thammasat University
2012
When severe, COVID-19 shares many clinical features with bacterial sepsis. Yet, secondary infection is uncommon. However, as epithelium injured and barrier function lost, products entering the circulation might contribute to pathophysiology of COVID-19. We studied 19 adults, severely ill patients infection, who were admitted King Chulalongkorn Memorial Hospital, Bangkok, Thailand, between 13th March 17th April 2020. Blood samples on days 1, 3, 7 enrollment analyzed for endotoxin activity...
Dengue is the most common mosquito-borne flaviviral infection in world today. Several factors contribute and act synergistically to cause severe infection. One of these dysregulated host immunological mediators that transient pathophysiology during These on endothelium increase vascular permeability, which leads plasma leakage compromising hemodynamics coagulopathy. We conducted a prospective study explore expression pro- anti-inflammatory cytokines how they relate clinical dengue...
Patients exposed to a rabid animal often travel long distances receive postexposure prophylaxis (PEP), which requires 4 or 5 visits. Reducing the number of clinic visits would not only reduce costs for patient but may also help increase compliance complete PEP. We made an effort develop PEP completed in 1 week.We administered 4-site intradermal injections 0.1 mL purified Vero cell rabies vaccine deltoids and thighs on days 0, 3, 7, with without equine immunoglobulin (40 IU/kg). A control...
Human immunodeficiency virus (HIV)–infected patients with low CD4+ T lymphocyte counts had a poor neutralizing antibody response to pre- and postexposure rabies vaccination. This study of HIV-infected <200/μL indicated that after 4-site intradermal vaccinations (4-4-4-0-2-2, doubling the doses cell-culture vaccine).
We report an atypical case of paralytic rabies presenting with trismus followed by limb weakness, areflexia, ophthalmoparesis, and bilateral ptosis. Atypical presentations history postexposure prophylaxis led to delayed diagnosis. Nucleocapsid glycoprotein genes viruses from the patient's biting dog's brains were identical sequences.
Background Each year millions of travelers visit Southeast Asia where rabies is still prevalent. This study aimed to assess the risk exposure, i.e., by being bitten or licked an animal, among in Asia. The secondary objective was their attitudes and practices related rabies. Methodology/Principal Findings Foreign departing destination outside were invited fill out questionnaire departure hall Bangkok International Airport. They asked about demographic profile, travel characteristics,...
There has been an alarming increase in the number of HIV-infected children worldwide [1]. Dog bites are a serious publichealth problem developing countries, and one-fourth chil-dren Thailand have experienced animal [2]. We con-ducted this study to evaluate safety immunogenicity ofrabies vaccine infected with HIV type 1 (HIV-1).HDCV (human diploid-cell rabies vaccine, lot 0544, antigencontent 9.3 IU/mL; Institut Merieux, Lyon, France) wasgiven 13 HIV-1–infected (study group) 9 healthychildren...
Although pertussis has been considered a disease of childhood, it is also recognized as an important respiratory tract infection in adolescents and adults. However, countries with routine vaccination against high coverage, not usually taken into consideration for the etiology prolonged cough Previous studies variety populations developed have documented that quite common, ranging from 2.9 to 32 % adults cough. The anticipation early recognition this change epidemiology because affected act...
Background: The 7th Asia Dengue Summit (ADS), titled “Road Map to Zero Death”, was held in Malaysia from 5 7 June 2024. summit co-organized by Voice and Action (ADVA); Global Aedes-Transmitted Diseases Consortium (GDAC); Southeast Asian Ministers of Education Tropical Medicine Public Health Network (SEAMEO TROPMED); Fondation Mérieux (FMx); the International Society for Neglected (ISNTD). Objectives: experts academia research, as well representatives Ministries Health, Regional World...
We report the case of a 6-y-old HIV-infected girl with severe immune deficiency who failed to respond intramuscular pre-exposure rabies vaccination using human diploid cell vaccine on days 0, 7 and 28. She also an intradermal postexposure regimen purified verocell at 4 sites 3 2 30 90 (double usual regimen). Sequentially monitored neutralizing antibody titers were below WHO minimum acceptable level (> 0.15 IU/ml) in all specimens. Rabies prevention persons suppression requires further study.
Complicated skin and structure infections (cSSSIs) frequently result in hospitalization with significant morbidity mortality. In this phase 3b/4 parallel, randomized, open-label, comparative study, 531 subjects cSSSI received tigecycline (100 mg initial dose, then 50 intravenously every 12 hrs) or ampicillin-sulbactam 1.5-3 g IV 6 hrs amoxicillin-clavulanate 1.2 6-8 hrs. Vancomycin could be added at the discretion of investigator to comparator arm if methicillin-resistant Staphylococcus...
BackgroundRabies has become a forgotten and neglected disease in Japan. In 2006, there was slight increase social awareness of rabies when Japan had two reported cases human rabies, originating the Philippines. Although number Japanese either traveling or living other Asian countries been increasing, exact risk this population contracting is unknown. Thus, study utilized questionnaire to investigate incidence exposure, as well knowledge, attitude, practice toward prevention among expatriates...
Abstract Purpose When severe, COVID-19 shares many clinical features with bacterial sepsis. Yet, secondary infection is uncommon. However, as epithelium are injured and barrier function lost, products entering the circulation might contribute to pathophysiology of COVID-19. Methods We studied 19 adults, severely ill patients infection, who were admitted King Chulalongkorn Memorial Hospital, Bangkok, Thailand, between 13 th March 17 April 2020. Blood samples on day 1, 3, 7 enrollment analyzed...