A5002034222- Enzyme Catalysis and Immobilization
- Pancreatic function and diabetes
- Lipid metabolism and biosynthesis
- Infant Nutrition and Health
- Diabetes Management and Research
- Diet and metabolism studies
- Pharmacology and Obesity Treatment
- Proteins in Food Systems
- Microbial Metabolic Engineering and Bioproduction
- Diet, Metabolism, and Disease
- Clinical Nutrition and Gastroenterology
- Breastfeeding Practices and Influences
- Neonatal Respiratory Health Research
- Analytical Chemistry and Chromatography
- Lipid Membrane Structure and Behavior
- Algal biology and biofuel production
- Biochemical Analysis and Sensing Techniques
- Plant biochemistry and biosynthesis
- Pancreatitis Pathology and Treatment
- Muscle metabolism and nutrition
- Digestive system and related health
- Drug Solubulity and Delivery Systems
- Fatty Acid Research and Health
- Diabetes and associated disorders
- Photosynthetic Processes and Mechanisms
Bioénergétique et Ingénierie des Protéines
2014-2025
Centre National de la Recherche Scientifique
2016-2025
Aix-Marseille Université
2015-2024
Délégation Provence et Corse
2014-2020
Institute of Molecular Life Sciences
2005-2017
Centre National pour la Recherche Scientifique et Technique (CNRST)
1992-2017
Institut de Physique de Rennes
2016
Bipar
2014
Architecture et Fonction des Macromolécules Biologiques
1997-2008
Territoires
2008
The paper presents an international consensus for a standardised static<italic>in vitro</italic>digestion method food.
Developing a mechanistic understanding of the impact food structure and composition on human health has increasingly involved simulating digestion in upper gastrointestinal tract. These simulations have used wide range different conditions that often very little physiological relevance, this impedes meaningful comparison results. The standardized protocol presented here is based an international consensus developed by COST INFOGEST network. method designed to be with standard laboratory...
Standardised recommendations for a physiologically relevant, semi-dynamic <italic>in vitro</italic> simulation of upper GI tract digestion.
Understanding the mechanisms of food digestion is paramount importance to determine effect foods have on human health. Significant knowledge fate during has been generated in healthy adults due development physiologically-relevant vitro models. However, it appears that performance oro-gastrointestinal tract affected by ageing and a model simulating digestive conditions found younger adult (<65 years) not relevant for an older (>65 years). The objectives present paper were: (1) conduct...
Summary The early light‐induced proteins (ELIPs) belong to the multigenic family of pigment‐binding light‐harvesting complexes. ELIPs accumulate transiently and are believed play a protective role in plants exposed high levels light. Constitutive expression ELIP2 gene Arabidopsis resulted marked reduction pigment content chloroplasts, both mature leaves during greening etiolated seedlings. chlorophyll loss was associated with decrease number photosystems thylakoid membranes, but present were...
Background Few studies have tested the small intestine microbiota in humans, where most nutrient digestion and absorption occur. Here, our objective was to examine duodenal between obese normal volunteers using metagenomic techniques. Methodology/Principal Findings We samples from five 16S rDNA V6 pyrosequencing Illumina MiSeq deep sequencing. The predominant phyla of were Firmicutes Actinobacteria, whereas Bacteroidetes absent. Obese individuals had a significant increase anaerobic genera...
The LFCS Consortium was established to develop standardized in vitro tests for lipid-based formulations (LBFs) and examine the utility of these probe fundamental mechanisms that underlie LBF performance. In this publication, impact bile salt (sodium taurodeoxycholate, NaTDC) concentration drug loading on ability a range representative LBFs generate sustain solubilization supersaturation during digestion testing has been explored common driver potential precipitation identified. Danazol used...
Some Lactobacillus species are associated with obesity and weight gain while others loss. spp. bifidobacteria represent a major bacterial population of the small intestine where lipids simple carbohydrates absorbed, particularly in duodenum jejunum. The objective this study was to identify proteins involved carbohydrate lipid metabolism modifications.We examined total 13 complete genomes belonging seven different previously or protection. We combined data obtained from Rapid Annotation using...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA structural domain (the lid) found in pancreatic lipases is absent the guinea pig (phospho)lipaseAnnegrethe Hjorth, Frederic Carriere, Claire Cudrey, Helle Woldike, Esper Boel, David M. Lawson, Francine Ferrato, Christian Cambillau, Guy G. Dodson, and Cite this: Biochemistry 1993, 32, 18, 4702–4707Publication Date (Print):May 11, 1993Publication History Published online1 May 2002Published inissue 11...
The inhibition of digestive lipases by the antiobesity drug Orlistat along with lipolysis levels and fecal fat excretion were measured in healthy humans. was found to be a powerful gastric lipase inhibitor, achieving 46.6–91.4% enzyme thus greatly reducing solid liquid meals (11–33% respective controls). Gastric extremely fast (half-inhibition time < 1 min). Duodenal reduced significantly given meal (32.6–37.6% controls) but only slightly (74.5–100% Human pancreatic (HPL) high...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEvidence for a Pancreatic Lipase Subfamily with New Kinetic PropertiesKenneth Thirstrup, Robert Verger, and Frederic CarriereCite this: Biochemistry 1994, 33, 10, 2748–2756Publication Date (Print):March 15, 1994Publication History Published online1 May 2002Published inissue 15 March 1994https://pubs.acs.org/doi/10.1021/bi00176a002https://doi.org/10.1021/bi00176a002research-articleACS PublicationsRequest reuse permissionsArticle...