Melin Özgün Geçer

ORCID: 0000-0003-4849-0793
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Soft tissue tumor case studies
  • Cancer and Skin Lesions
  • Sarcoma Diagnosis and Treatment
  • Breast Implant and Reconstruction
  • Cervical Cancer and HPV Research
  • Tumors and Oncological Cases
  • Gastric Cancer Management and Outcomes
  • Genital Health and Disease
  • HER2/EGFR in Cancer Research
  • Cancer Diagnosis and Treatment
  • Colorectal and Anal Carcinomas
  • Glycosylation and Glycoproteins Research
  • Endometrial and Cervical Cancer Treatments
  • Breast Lesions and Carcinomas
  • Galectins and Cancer Biology
  • Gastrointestinal Tumor Research and Treatment
  • Breast Cancer Treatment Studies
  • Cancer Cells and Metastasis
  • Metastasis and carcinoma case studies
  • Renal and related cancers
  • Acute Kidney Injury Research
  • Bariatric Surgery and Outcomes
  • Ocular Infections and Treatments
  • Genetic and rare skin diseases.
  • Advanced Glycation End Products research

Bezmiâlem Vakıf Üniversitesi
2016-2024

Marconi University
2020

Central Michigan University
2020

Michigan United
2020

Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2007-2015

Diabetes mellitus is a multisystemic metabolic disorder that may affect the eyes, kidneys, vessels, and heart. Chronic hyperglycemia causes non-enzymatic glycation of proteins elevation polyol pathway resulting in oxidative stress damages organs. The current study aimed to investigate dose-dependent effects orally consumed Rosa damascena Mill. hydrosol on hematology, clinical biochemistry, lens enzymatic activity, pathology streptozotocin (STZ)-induced diabetic rats. was induced into male...

10.3390/molecules24224069 article EN cc-by Molecules 2019-11-10

Objective. To report a case of toxic anterior segment syndrome (TASS) that was caused by inadvertent chamber and cornea stromal injection with high dose gentamicin following cataract surgery. Methods. Case report. Results. We 72-year-old female patient who developed TASS (20 mg/0.5 mL), which inadvertently used during the formation hydration corneal incision. Unlike previous cases, hyphema hemorrhagic fibrinous reaction were seen in chamber. Despite treatment, bullous keratopathy penetrating...

10.1155/2014/143564 article EN cc-by Case Reports in Medicine 2014-01-01

Metastasis in the axillary lymph nodes is most important known prognostic factor for breast cancer. We aimed to investigate contribution of radioisotope tracer method dye-only by performing sentinel node biopsy on same patient group during a single surgical session.Forty-two patients who underwent operations our clinic from February 2010 October 2011 and with masses <5 cm clinically radiologicallly negative axilla (T1-2 N0) were prospectively included this study. After paraffin examination...

10.1186/1471-2482-13-13 article EN cc-by BMC Surgery 2013-04-25

Seroma formation is the most common complication after breast cancer surgery. It an important since it prolongs therapy duration, increases cost, and negatively affects patient psychology. Currently, there no widely accepted method that prevents seroma formation. We tried to investigate impact of local phenytoin application on following experimental mastectomy model created in rats.Two groups including eight rats each were randomized. Saline injection was applied first group, whereas 1%...

10.1186/1471-2482-12-25 article EN cc-by BMC Surgery 2012-12-01

This study aimed to determine the rates of distribution high-risk HPV (hrHPV) genotypes according cervical smear samples and biopsy results in a large sample Turkish women.

10.4103/joc.joc_129_22 article EN cc-by-nc-sa Journal of Cytology 2023-01-01

Amaç: bu çalışmada, Her-2 durumları önceden immünohistokimyasal olarak skor 0 veya 1+ tanımlanmış meme karsinomu olgularında silver in situ hibridizasyon ile tekrar test yapılarak pozitiflik oranının tespit edilmesi amaçlanmıştır.Gereç ve Yöntem: Çalışmada 9 merkezin katkısıyla, 552 olgu değerlendirildi.Çalışmaya, immünohistokimya sonucu 0/1+ bulunmuş kanseri olguları alındı.bu olgulara ait parafin blok kesitlerinde merkez laboratuvarında durumu yöntemiyle yeniden değerlendirildi.Her-2 gen...

10.5146/tjpath.2014.01240 article TR cc-by Turkish Journal of Pathology 2014-01-01

Ovarian metasteses are often mistaken for primary adenocarcinoma. Studies conducted in recent years have focused on a search an immunohistochemical marker to aid the differential diagnosis and metastatic ovarian carcinoma. Our study objective was usefulness of Wilms tumor 1 (WT 1) antigen this context.The at pathology clinic Lütfi Kırdar Training Research Hospital. Deparaffinated blocks 40 epithelial tumors, colon adenocarcinomas, 35 cases omentum metastases were studied. Cytokeratin 7 (CK...

10.4274/tjod.22220 article EN Journal of Turkish Society of Obstetric and Gynecology 2016-03-20

Fingolimod is an oral disease-modifying treatment used for the relapsing-remitting forms of multiple sclerosis, which may render patients susceptible to opportunistic infections and lead increased risk skin cancer. We report a 56-year-old woman with sclerosis in remission on fingolimod five years presenting following lesions. Our patient presented non-healing ulcerated erythematous lesion left lower abdomen six months crusted plaque forehead that had not healed one year. Skin biopsy from...

10.7759/cureus.71050 article EN Cureus 2024-10-08

Objectives: Gastric carcinoma (GC) is the fourth most common cause of cancer-related tumor deaths worldwide. The prognostic significance CD44, CD133 and human epidermal growth factor receptor 2 (HER2) expression in GC remains controversial. Therefore, we aimed to investigate relationship HER2 with clinicopathological features metastatic non-metastatic patients. Methods: A total 139 patients (68 metastasis, 71 without metastasis) diagnosed were retrospectively analyzed. CD44 determined by...

10.18621/eurj.1296567 article EN The European Research Journal 2023-08-08

Liver function is affected by ischemiareperfusion. Ischemia-reperfusion injury to the liver often follows hepatobiliary surgery. Here, we investigated biomarkers of ischemia-reperfusion using an animal model.

10.6002/ect.2021.0023 article EN Experimental and Clinical Transplantation 2021-08-09

Objective: Breast carcinomas positive for the estrogen receptor (ER+) but negative progesterone (PR-) have unfavorable prognostic features and are resistant to tamoxifen therapy.The goal of this study was highlight significance PR-breast carcinomas.Methods: Therefore, 146 breast comprising 87 ER+/PR+ 59 ER+/PR-carcinomas were examined.These two groups compared in terms age; tumor type; size; histologic grade; presence an situ component; lymphovascular perineural invasion; ER, PR, c-Erb B2,...

10.14235/bs.2015.493 article EN cc-by-nc-nd Bezmialem Science 2015-09-22

Objective: Galectin-3 is an endogenous β-galactoside binding protein which S-type lectin family member with intracellular and extracellular localization has certain tasks for controlling cell adhesion, growth, proliferation, differentiation, migration, apoptosis. In this study we aimed to elucidate the role of galectin-3 expression in metastasis biology its predicting tumor colon carcinomas.&#x0D; Materials Method: research, 80 cases adenocarcinoma containing transition normal mucosa-tumor...

10.33716/bmedj.1233053 article EN Balıkesir Medical Journal 2023-01-29

Objective: Colon adenocarcinomas are the most common gastrointestinal tract malignancy and constitute one of leading causes mortality morbidity worldwide. STAT3 is a transcription factor activated by many cytokines growth factors plays crucial role in cell survival, proliferation, differentiation. In this research, we aimed to elucidate molecular properties colon tumors. Materials &amp; Methods:A total 196 patients with metastatic tumors whose samples were analyzed for KRAS, NRAS, BFAF...

10.5455/annalsmedres.2023.04.103 article EN cc-by-nc-nd Annals of Medical Research 2023-01-01
Coming Soon ...