- Soft tissue tumor case studies
- Cancer and Skin Lesions
- Sarcoma Diagnosis and Treatment
- Breast Implant and Reconstruction
- Cervical Cancer and HPV Research
- Tumors and Oncological Cases
- Gastric Cancer Management and Outcomes
- Genital Health and Disease
- HER2/EGFR in Cancer Research
- Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Glycosylation and Glycoproteins Research
- Endometrial and Cervical Cancer Treatments
- Breast Lesions and Carcinomas
- Galectins and Cancer Biology
- Gastrointestinal Tumor Research and Treatment
- Breast Cancer Treatment Studies
- Cancer Cells and Metastasis
- Metastasis and carcinoma case studies
- Renal and related cancers
- Acute Kidney Injury Research
- Bariatric Surgery and Outcomes
- Ocular Infections and Treatments
- Genetic and rare skin diseases.
- Advanced Glycation End Products research
Bezmiâlem Vakıf Üniversitesi
2016-2024
Marconi University
2020
Central Michigan University
2020
Michigan United
2020
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2007-2015
Diabetes mellitus is a multisystemic metabolic disorder that may affect the eyes, kidneys, vessels, and heart. Chronic hyperglycemia causes non-enzymatic glycation of proteins elevation polyol pathway resulting in oxidative stress damages organs. The current study aimed to investigate dose-dependent effects orally consumed Rosa damascena Mill. hydrosol on hematology, clinical biochemistry, lens enzymatic activity, pathology streptozotocin (STZ)-induced diabetic rats. was induced into male...
Objective. To report a case of toxic anterior segment syndrome (TASS) that was caused by inadvertent chamber and cornea stromal injection with high dose gentamicin following cataract surgery. Methods. Case report. Results. We 72-year-old female patient who developed TASS (20 mg/0.5 mL), which inadvertently used during the formation hydration corneal incision. Unlike previous cases, hyphema hemorrhagic fibrinous reaction were seen in chamber. Despite treatment, bullous keratopathy penetrating...
Metastasis in the axillary lymph nodes is most important known prognostic factor for breast cancer. We aimed to investigate contribution of radioisotope tracer method dye-only by performing sentinel node biopsy on same patient group during a single surgical session.Forty-two patients who underwent operations our clinic from February 2010 October 2011 and with masses <5 cm clinically radiologicallly negative axilla (T1-2 N0) were prospectively included this study. After paraffin examination...
Seroma formation is the most common complication after breast cancer surgery. It an important since it prolongs therapy duration, increases cost, and negatively affects patient psychology. Currently, there no widely accepted method that prevents seroma formation. We tried to investigate impact of local phenytoin application on following experimental mastectomy model created in rats.Two groups including eight rats each were randomized. Saline injection was applied first group, whereas 1%...
This study aimed to determine the rates of distribution high-risk HPV (hrHPV) genotypes according cervical smear samples and biopsy results in a large sample Turkish women.
Amaç: bu çalışmada, Her-2 durumları önceden immünohistokimyasal olarak skor 0 veya 1+ tanımlanmış meme karsinomu olgularında silver in situ hibridizasyon ile tekrar test yapılarak pozitiflik oranının tespit edilmesi amaçlanmıştır.Gereç ve Yöntem: Çalışmada 9 merkezin katkısıyla, 552 olgu değerlendirildi.Çalışmaya, immünohistokimya sonucu 0/1+ bulunmuş kanseri olguları alındı.bu olgulara ait parafin blok kesitlerinde merkez laboratuvarında durumu yöntemiyle yeniden değerlendirildi.Her-2 gen...
Ovarian metasteses are often mistaken for primary adenocarcinoma. Studies conducted in recent years have focused on a search an immunohistochemical marker to aid the differential diagnosis and metastatic ovarian carcinoma. Our study objective was usefulness of Wilms tumor 1 (WT 1) antigen this context.The at pathology clinic Lütfi Kırdar Training Research Hospital. Deparaffinated blocks 40 epithelial tumors, colon adenocarcinomas, 35 cases omentum metastases were studied. Cytokeratin 7 (CK...
Fingolimod is an oral disease-modifying treatment used for the relapsing-remitting forms of multiple sclerosis, which may render patients susceptible to opportunistic infections and lead increased risk skin cancer. We report a 56-year-old woman with sclerosis in remission on fingolimod five years presenting following lesions. Our patient presented non-healing ulcerated erythematous lesion left lower abdomen six months crusted plaque forehead that had not healed one year. Skin biopsy from...
Objectives: Gastric carcinoma (GC) is the fourth most common cause of cancer-related tumor deaths worldwide. The prognostic significance CD44, CD133 and human epidermal growth factor receptor 2 (HER2) expression in GC remains controversial. Therefore, we aimed to investigate relationship HER2 with clinicopathological features metastatic non-metastatic patients. Methods: A total 139 patients (68 metastasis, 71 without metastasis) diagnosed were retrospectively analyzed. CD44 determined by...
Liver function is affected by ischemiareperfusion. Ischemia-reperfusion injury to the liver often follows hepatobiliary surgery. Here, we investigated biomarkers of ischemia-reperfusion using an animal model.
Objective: Breast carcinomas positive for the estrogen receptor (ER+) but negative progesterone (PR-) have unfavorable prognostic features and are resistant to tamoxifen therapy.The goal of this study was highlight significance PR-breast carcinomas.Methods: Therefore, 146 breast comprising 87 ER+/PR+ 59 ER+/PR-carcinomas were examined.These two groups compared in terms age; tumor type; size; histologic grade; presence an situ component; lymphovascular perineural invasion; ER, PR, c-Erb B2,...
Objective: Galectin-3 is an endogenous β-galactoside binding protein which S-type lectin family member with intracellular and extracellular localization has certain tasks for controlling cell adhesion, growth, proliferation, differentiation, migration, apoptosis. In this study we aimed to elucidate the role of galectin-3 expression in metastasis biology its predicting tumor colon carcinomas.
 Materials Method: research, 80 cases adenocarcinoma containing transition normal mucosa-tumor...
Objective: Colon adenocarcinomas are the most common gastrointestinal tract malignancy and constitute one of leading causes mortality morbidity worldwide. STAT3 is a transcription factor activated by many cytokines growth factors plays crucial role in cell survival, proliferation, differentiation. In this research, we aimed to elucidate molecular properties colon tumors. Materials & Methods:A total 196 patients with metastatic tumors whose samples were analyzed for KRAS, NRAS, BFAF...