A5056580459- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Quantum Computing Algorithms and Architecture
- Blockchain Technology Applications and Security
- Image Retrieval and Classification Techniques
- Genomics and Phylogenetic Studies
- Neural Networks and Reservoir Computing
- Quantum Information and Cryptography
Simon Fraser University
2021-2022
The occurrence of multiple strains a bacterial pathogen such as M. tuberculosis or C. difficile within single human host, referred to mixed infection, has important implications for both healthcare and public health. However, methods detecting it, especially determining the proportion identities underlying strains, from WGS (whole-genome sequencing) data, have been limited. In this paper we introduce SplitStrains, novel method addressing these challenges. Grounded in rigorous statistical...
An essential consideration in urban transit facility planning is service efficiency and accessibility. Previous research has shown that reducing the number of facilities along a route may increase but decrease Striking balance between these two critical planning. Transit consolidation cost-effective way to improve quality by strategically determining desirable allocation limited facilities. This paper develops an optimization framework integrates Geographical Information systems (GIS),...
We propose an approach to solving constrained combinatorial optimization problems based on embedding the concept of Lagrangian duality into framework discretized adiabatic quantum computation (DAQC). Within setting circuit-model fault-tolerant computation, we present numerical evidence that our achieves a quadratic improvement in circuit depth and maintains constraint-independent width, contrast prevalent via reformulations unconstrained binary (QUBO) formalism. Our study includes detailed...