A5000265206- Radiation Dose and Imaging
- Radioactive contamination and transfer
- Radiation Therapy and Dosimetry
- Radioactivity and Radon Measurements
- Medical Imaging Techniques and Applications
- Radiation Detection and Scintillator Technologies
- Advanced Radiotherapy Techniques
- Nuclear and radioactivity studies
- Radioactive Decay and Measurement Techniques
- Graphite, nuclear technology, radiation studies
- Radioactive element chemistry and processing
- Nuclear Physics and Applications
- Digital Radiography and Breast Imaging
- Particle Detector Development and Performance
- Carcinogens and Genotoxicity Assessment
- Lanthanide and Transition Metal Complexes
- Radiopharmaceutical Chemistry and Applications
- Effects of Radiation Exposure
- Advanced X-ray and CT Imaging
- Social and Demographic Issues in Germany
- Radiation Effects and Dosimetry
- Chemical Safety and Risk Management
- Health Systems, Economic Evaluations, Quality of Life
- Optical Imaging and Spectroscopy Techniques
- Social Policies and Healthcare Reform
Karlsruhe Institute of Technology
2011-2024
Helmholtz Zentrum München
2010
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2010
FZI Research Center for Information Technology
2009
FIZ Karlsruhe – Leibniz Institute for Information Infrastructure
2008
University of Cologne
2004
Klinik und Poliklinik für Nuklearmedizin
2004
Since 2012, the European Radiation Dosimetry Group (EURADOS) has developed its Strategic Research Agenda (SRA), which contributes to identification of future research needs in radiation dosimetry Europe. Continued scientific developments this field necessitate regular updates and, consequently, paper summarises latest revision SRA, with input regarding state art and vision for contributed by EURADOS Working Groups through a stakeholder workshop. Five visions define key issues that are...
The TECHREC project, funded by the European Commission, will provide Technical Recommendations for Monitoring Individuals Occupational Intakes of Radionuclides It is expected that document be published Commission as a report in its Radiation Protection Series during 2016. project coordinated Dosimetry Group (EURADOS) and being carried out members EURADOS Working 7 (Internal Dosimetry). This paper describes aims purpose Recommendations, explains how organised.
Diethylene Triamine Pentaacetic Acid (DTPA) is used for decorporation of plutonium because it known to be able enhance its urinary excretion several days after treatment by forming stable Pu-DTPA complexes. The prevents accumulation in organs and results a dosimetric benefit, which difficult quantify from bioassay data using existing models. development biokinetic model describing the mechanisms actinide administration DTPA was initiated as task European COordinated Network on RAdiation...
Abstract Decorporation therapy with salts of diethylenetriamine-pentaacetic acid binds actinides, thereby limiting uptake to organs and enhancing the rate at which actinides are excreted in urine. International Commission on Radiological Protection reference biokinetic models cannot be used fit this enhanced exertion simultaneously baseline actinide excretion that is observed prior start and/or after effects have ceased. In study, Coordinated Network Radiation Dosimetry approach, was...
Parameter uncertainties for the biokinetic model of caesium (Cs) developed by Leggett et al. were inventoried and evaluated. The methods parameter uncertainty analysis used to assess predictions with assumptions distributions. Furthermore, importance individual parameters was assessed means sensitivity analysis. calculated compared human data Cs measured in blood whole body. It found that propagating derived values reproduced range bioassay observed subjects at different times after intake....
To develop a physiologically based compartmental approach for modeling plutonium decorporation therapy with the chelating agent Diethylenetriaminepentaacetic acid (Ca-DTPA/Zn-DTPA).Model calculations were performed using software package SAAM II (©The Epsilon Group, Charlottesville, Virginia, USA). The Luciani/Polig model age-dependent description of bone recycling processes was used biokinetics plutonium.The slightly modified in order to account speciation blood and different affinities...
European Radiation Dosimetry Group e.V. (EURADOS) survey on individual monitoring data and dose assessment has been carried out for 550 foreigners returning home after being exposed in Japan to intakes of radionuclides (mainly (131)I, (132)I, (132)Te, (134)Cs (137)Cs) as a consequence the Fukushima Daiichi NPP accident. In vivo vitro measurements were performed their respective countries at an early stage that Intakes detected 208 persons from Europe Canada, but committed effective E(50) was...
EURADOS working group on 'Internal Dosimetry (WG7)' represents a frame to develop activities in the field of internal exposures as coordinated actions quality assurance (QA), research and training. The main tasks carry out are update IDEAS Guidelines reference document for dosimetry community, implementation QA new ICRP biokinetic models, assessment uncertainties related models their application, development physiology-based biokinetics radionuclides, stable isotope studies, modelling...
European Radiation Dosimetry Group (EURADOS) Working 7 is a network on internal dosimetry that brings together researchers from more than 60 institutions in 21 countries. The work of the group organised into task groups focus different aspects, such as development and implementation biokinetic models (e.g. for diethylenetriamine penta-acetic acid decorporation therapy), individual monitoring dose assessment process, Monte Carlo simulations dosimetry, uncertainties microdosimetry. Several...
Virtual models of real phantoms used with Monte Carlo methods facilitate the calibration and other studies associated whole-body partial-body counting systems. In this investigation, a voxel model an LLNL torso phantom, available physically in vivo laboratory at KIT, was created from computed tomography scans. Series measurements high-purity germanium detector loaded different radioactive organs, have been carried out. Computer simulations these measurement setups were performed aid MCNPX,...
Journal Article 30-y follow-up of a Pu/Am inhalation case Get access Christian Wernli, Wernli * 1Paul Scherrer Institute (PSI), Villigen, Switzerland *Corresponding author: christian.wernli@alumni.ethz.ch Search for other works by this author on: Oxford Academic PubMed Google Scholar Jost Eikenberg, Eikenberg Olaf Marzocchi, Marzocchi 2Karlsruhe Technology (KIT), Karlsruhe, Germany Bastian Breustedt, Breustedt Ursula Oestreicher, Oestreicher 3Federal Office Radiation Protection (BfS),...
Monte Carlo (MC) methods are numerical simulation techniques that can be used to extend the scope of calibrations performed in vivo monitoring laboratories. These allow carried out for a much wider range body shapes and sizes than would feasible using physical phantoms. Unfortunately, nowadays, this powerful technique is still mainly research institutions only. In 2013, EURADOS laboratory Karlsruhe Institute Technology (KIT) organized 3-d training course disseminate knowledge on application...
The work of the Task Group 5.2 ‘Research Studies on Biokinetic Models’ CONRAD project is presented. New biokinetic models have been implemented by several European institutions. Quality assurance procedures included intercomparison results as well quality model formulation. Additionally, use was examined leading to proposals tuning parameters. Stable isotope studies were evaluated with respect their implications new models, and proposed basis results. Furthermore, development a describing...
The CONRAD Project is a Coordinated Network for Radiation Dosimetry funded by the European Commission 6th Framework Programme. activities developed within Work Package 5 ('Coordination of Research on Internal Dosimetry') have contributed to improve harmonisation and reliability in assessment internal doses. tasks carried out included study uncertainties refinement IDEAS Guidelines associated with evaluation doses after intakes radionuclides. implementation quality assurance new biokinetic...
Journal Article Analysis of the effects inter-individual variation in distribution plutonium skeleton and liver Get access W. Klein, Klein * Karlsruhe Institute Technology (KIT), for Nuclear Waste Disposal (INE), Karlsruhe, Germany *Corresponding author: wolfgang.klein@kit.edu Search other works by this author on: Oxford Academic PubMed Google Scholar B. Breustedt Radiation Protection Dosimetry, Volume 158, Issue 3, February 2014, Pages 276–284, https://doi.org/10.1093/rpd/nct233 Published:...
A goal of whole body counting (WBC) is the estimation total burden radionuclides disregarding actual position within body. To achieve goal, detectors need to be placed in regions where photon flux as independent possible from distribution source. At same time, high fluxes order better efficiency and lower minimum detectable activities. This work presents a method able define layout new WBC systems study behaviour existing ones using both detection its dependence on source computational phantoms.
This paper describes new biokinetic and dosimetric models, especially those being developed by ICRP which will be used in the forthcoming documents on Occupational Intakes of Radionuclides. It also presents results a working group within European project CONRAD is continued EURADOS. implementing performing quality assurance model implementation (including their description) giving guidance to scientific community application models for individual dose assessment.
This paper provides a summary of the Education and Training (E&T) activities that have been developed organised by European Radiation Dosimetry Group (EURADOS) in recent years case Courses over last decade. These E&T actions include short duration on well-established topics within activity EURADOS Working Groups (WGs), or one-day events integrated Annual Meeting (workshops, winter schools, intercomparison participants' sessions learning network, among others). Moreover, has recently...