Mark J. La Guardia

ORCID: 0000-0003-4866-4992
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About
Contact & Profiles
Research Areas
  • Toxic Organic Pollutants Impact
  • Air Quality and Health Impacts
  • Effects and risks of endocrine disrupting chemicals
  • Microplastics and Plastic Pollution
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Carcinogens and Genotoxicity Assessment
  • Mercury impact and mitigation studies
  • Atmospheric chemistry and aerosols
  • Recycling and Waste Management Techniques
  • Environmental Justice and Health Disparities
  • Per- and polyfluoroalkyl substances research
  • Occupational Health and Performance
  • Environmental Toxicology and Ecotoxicology
  • Oil Spill Detection and Mitigation
  • Heavy metals in environment
  • biodegradable polymer synthesis and properties
  • Noise Effects and Management
  • Skin Protection and Aging
  • Flame retardant materials and properties
  • Dermatological diseases and infestations
  • Autoimmune Neurological Disorders and Treatments
  • Fire effects on ecosystems
  • Traffic and Road Safety
  • Automotive and Human Injury Biomechanics
  • Phosphorus and nutrient management

William & Mary
2015-2024

National Institute for Occupational Safety and Health
2018

Virginia Institute of Marine Science
2004-2013

Moss Landing Marine Laboratories
2008

United States Fish and Wildlife Service
2008

National Wildlife Federation
2008

Boston University
2007

University of Massachusetts Lowell
2007

Polybrominated diphenyl ethers (PBDEs) have been widely used to flame-retard products common in homes and the workplace, subsequently, they become dispersed environment. Detailed compositional knowledge of these complex PBDE mixtures is crucial a fuller understanding their toxicological potencies environmental fate due selective congener biomagnification, degradation, transport. Utilizing recent technical enhancements newly available commercial standards, we developed method capable...

10.1021/es060630m article EN Environmental Science & Technology 2006-09-16

Abstract Society has become increasingly reliant on plastics since commercial production began in about 1950. Their versatility, stability, light weight, and low costs have fueled global demand. Most are initially used discarded land. Nonetheless, the amount of microplastics some oceanic compartments is predicted to double by 2030. To solve this problem, we must understand plastic composition, physical forms, uses, transport, fragmentation into (and nanoplastics). Plastic...

10.1029/2018jc014719 article EN publisher-specific-oa Journal of Geophysical Research Oceans 2020-01-01

This study was designed to determine the body burden of polybrominated diphenyl ethers (PBDEs) among first-time mothers in Greater Boston, Massachusetts area and explore key routes exposure. We collected breast milk samples from 46 mothers, 2−8 weeks after birth. also sampled house dust homes a subset participants by vacuuming commonly used areas. Data on personal characteristics, diet, home furniture, electrical devices were gathered each participant using questionnaire. Breast analyzed for...

10.1021/es0620282 article EN Environmental Science & Technology 2007-01-17

Levels of flame retardants in house dust and a transport pathway from homes to the outdoor environment were investigated communities near Columbia River Washington state (WA). Residential laundry wastewater collected 20 Vancouver Longview, WA analyzed for suite test hypothesis that collecting on clothing transferring water is source treatment plants (WWTPs) subsequently waterways. Influent effluent two WWTPs servicing these also retardants. A total 21 compounds detected dust, including...

10.1021/es502227h article EN Environmental Science & Technology 2014-09-17

Polybrominated diphenyl ethers (PBDEs) were examined in fish fillets collected from two large Virginia watersheds. Emphasis was on the tetra- to hexabrominated congeners since these exhibit greatest bioaccumulation and toxicological potentials. These are dominant constituents of Penta-, a commercial PBDE product used flame retard polyurethane foam. In 1999, North America accounted for98% global Penta-demand. Concentrations total ranged <5 47,900 microg/kg (lipid basis). BDE-47, one major...

10.1021/es010845q article EN Environmental Science & Technology 2001-10-30

Decabromodiphenyl ether (BDE-209) is a high production volume flame retardant. To date, regulation and control of its environmental release have been minimal. Once in the environment, BDE-209 may encounter conditions favoring debromination, potentially forming congeners with greater toxicity, bioaccumulation potential, persistence. However, (photolytic vivo) debromination has only demonstrated under laboratory scenarios. examine whether was likely field, PBDE congener profiles were tracked...

10.1021/es070728g article EN Environmental Science & Technology 2007-09-05

Contemporary studies of chemical contamination in Antarctica commonly focus on remnants historical local releases or long-range transport legacy pollutants. To protect the continent's pristine status, Antarctic Treaty's Protocol Environmental Protection prohibits importation persistent organic However, some polybrominated diphenyl ether (PBDE) congeners exhibit similar properties. Many modern polymer-containing products, e.g., home/office furnishings and electronics, contain percent levels...

10.1021/es702547a article EN Environmental Science & Technology 2008-01-23

Alkylphenol ethoxylates, widely used in commercial and household detergents the United States, can degrade during wastewater treatment process to more toxic, estrogenic, lipophilic compounds. These include octylphenol (OP), nonylphenols (NPs), nonylphenol monoethoxylates (NP1EOs), diethoxylates (NP2EOs). compounds have received considerable attention due their acute toxicity ability disrupt endocrine system. In Europe, regulations been established control impact on environment. this study,...

10.1021/es0109040 article EN Environmental Science & Technology 2001-11-15

Alternative brominated flame-retardants (BFRs), 2-ethylhexyl 2,3,4,5-tetrabromobenzoate (TBB), 2,3,4,5-tetrabromophthalate (TBPH), 1,2-bis(2,4,6-tribromophenoxy) ethane (BTBPE) and decabromodiphenyl (DBDPE), are now being detected in the environment. However, contaminant bioavailability is influenced by organisms' ecology (i.e., route of uptake) situ environmental factors. We observed that filter-feeding bivalve (Corbicula fluminea) grazing gastropod (Elimia proxima), collected downstream...

10.1021/es3004238 article EN Environmental Science & Technology 2012-05-09

Brominated flame-retardant (BFR) additives are present in many polymeric consumer products at percent levels. High environmental concentrations have been observed near cities and polymer, textile, electronics manufacturing centers. Most studies focused on European, North American, Asian locales. Releases likely rising most dramatically countries with weak human health regulation enforcement, demand for electrical electronic equipment (EEE) is escalating, importation of waste EEE occurs....

10.1021/es4020212 article EN Environmental Science & Technology 2013-07-30

This study evaluated workers' exposures to flame retardants, including polybrominated diphenyl ethers (PBDEs), organophosphate esters (OPEs), and other brominated retardants (BFRs), in various industries. The aimed characterize OPE metabolite urinary concentrations PBDE serum among workers from different industries, compare these between industries the general population, evaluate likely route of exposure (dermal or inhalation). results showed that chemical manufacturing had significantly...

10.1021/acs.est.3c09342 article EN Environmental Science & Technology 2024-05-03

A total of 114 peregrine falcon eggs from nests in Connecticut, Massachusetts, Maine, New Hampshire, Rhode Island, and Vermont were analyzed for polybrominanted diphenyl ethers (PBDEs). Eggs collected 1996 to 2006, excluding 1997 1998. Total PBDE concentrations ranged 74.5 6610 ng/g wet weight, with a median 440. These levels generally higher than those observed European eggs, but comparable North American seabird eggs. Congener patterns differed such seabirds dominated by BDE-153, followed...

10.1021/es8010749 article EN Environmental Science & Technology 2008-09-18

Polybrominated diphenyl ethers (PBDEs) have been used extensively to flame-retard polymers and textiles. These persistent chemicals enter wastewater streams following manufacture, use, disposal, concentrating in the settled solids during treatment. Land application of stabilized sewage sludge (known as biosolids) can contribute PBDEs terrestrial systems. Monitoring sludge/biosolids contaminant burdens may be valuable revealing trends societal chemical usage environmental release. In archived...

10.1021/es203149g article EN Environmental Science & Technology 2012-01-26
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