- Sports Performance and Training
- Exercise and Physiological Responses
- Sports injuries and prevention
- Muscle metabolism and nutrition
- Cardiovascular and exercise physiology
- Thermoregulation and physiological responses
- Genetics and Physical Performance
- Muscle activation and electromyography studies
- Body Composition Measurement Techniques
- Diet and metabolism studies
- Occupational Health and Performance
- Dental Trauma and Treatments
- Cardiovascular Effects of Exercise
- Dental Health and Care Utilization
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Multiple Myeloma Research and Treatments
- High Altitude and Hypoxia
- Biochemical effects in animals
- Bone health and osteoporosis research
- Cancer Treatment and Pharmacology
- Genetics and Neurodevelopmental Disorders
- Obesity, Physical Activity, Diet
- Sport Psychology and Performance
- Dental Erosion and Treatment
- Restraint-Related Deaths
Arup Group (United Kingdom)
2024
Atlantic Technological University
2023
Letterkenny Institute of Technology
2021-2022
Northumbria University
2011-2020
GlaxoSmithKline (United Kingdom)
2013-2017
GlaxoSmithKline (Netherlands)
2017
University of East Anglia
2016
Nottingham Trent University
2016
Creative Commons
2016
Sports Science Institute of South Africa
2016
This investigation determined the efficacy of a tart cherry juice in aiding recovery and reducing muscle damage, inflammation oxidative stress. Twenty recreational Marathon runners assigned to either consumed or placebo for 5 days before, day 48 h following run. Markers damage (creatine kinase, lactate dehydrogenase, soreness isometric strength), [interleukin-6 (IL-6), C-reactive protein (CRP) uric acid], total antioxidant status (TAS) stress [thiobarbituric acid reactive species (TBARS)...
Abstract It is unknown if adult human skeletal muscle has an epigenetic memory of earlier encounters with growth. We report, for the first time in humans, genome-wide DNA methylation (850,000 CpGs) and gene expression analysis after hypertrophy (loading), return mass to baseline (unloading), followed by later (reloading). discovered increased frequency hypomethylation across genome reloading (18,816 versus loading (9,153 CpG sites). also identified AXIN1, GRIK2, CAMK4, TRAF1 as...
The aims of the study were to modify training impulse (TRIMP) method quantifying load for use with intermittent team sports, and examine relationship between this modified TRIMP (TRIMP(MOD)) changes in physiological profile sport players during a competitive season. Eight male field hockey players, participating English Premier Division, took part (mean+/-s: age 26+/-4 years, body mass 80.8+/-5.2 kg, stature 1.82+/-0.04 m). Participants performed three treadmill exercise tests at start...
We hypothesized that a bout of high or low volume eccentric exercise would protect against muscle damage following subsequent and adaptation be attributable to neural changes, independent the initial volume. Sixteen males performed either 45 (ECC45) 10 (ECC10) maximal contractions using elbow flexors, followed by an ECC45 2 weeks later. Damage markers were measured for 96 h; EMG work done during first also recorded. CK, soreness, decrements in MVC range motion (ROM) greater 1 than (p <...
Abstract DNA methylation is an important epigenetic modification that can regulate gene expression following environmental encounters without changes to the genetic code. Using Infinium MethylationEPIC BeadChip Arrays (850,000 CpG sites) we analysed for first time, isolated from untrained human skeletal muscle biopsies (vastus lateralis) at baseline (rest) and immediately acute (single) bout of resistance exercise. In same participants, also methylome a period growth (hypertrophy) evoked via...
This study examined the effects of β-hydroxy-β-methylbutyrate (HMB) and α-ketoisocaproic acid (KIC) supplementation on signs symptoms exercise-induced muscle damage following a single bout eccentrically biased resistance exercise. Six non-resistance trained male subjects performed an exercise protocol designed to induce two separate occasions, dominant or non-dominant arm in counter-balanced crossover design. Subjects were assigned HMB/KIC (3 g HMB 0.3 acid, daily) placebo treatment for 14 d...
The purpose of this investigation was to, firstly, examine the effects repeated applications ice massage on indirect markers associated with muscle damage using a within‐subjects cross‐over design and secondly, to how affects function in both static dynamic contractions following unaccustomed eccentric exercise. Twelve males performed damaging exercise two separate occasions. protocol consisted three sets 10 maximal repetitions elbow flexors isokinetic dynamometry. Subjects were randomly...
Abstract Background Exercise programmes are beneficial for cancer patients however evidence is limited in with multiple myeloma (MM), a that characterised by osteolytic bone disease, giving rise to high levels of morbidity including fractures and pain. Methods We conducted single arm phase 2 study an exercise programme (EP) as rehabilitation treated MM patients, evaluate feasibility, effects on QOL physiological parameters. Patients were given individualised programmes, comprising...
Hill, JA, Howatson, G, van Someren, KA, Walshe, I, and Pedlar, CR. Influence of compression garments on recovery after marathon running. J Strength Cond Res 28(8): 2228–2235, 2014—Strenuous physical activity can result in exercise-induced muscle damage. The purpose this study was to investigate the efficacy a lower limb garment accelerating from run. Twenty four subjects (female, n = 7; male, 17) completed run before being assigned treatment group or sham group. wore tights for 72 hours run,...
Introduction This case study reports a range of physiological characteristics in two-time Tour de France champion. Methods After body composition assessment (dual-energy x-ray absorptiometry), two submaximal cycling step tests were performed ambient (20°C, 40%) and hot humid (30°C, 60% [HH]) conditions from which measures gross efficiency (GE), lactate-power landmarks, heart rate responses calculated. In addition, thermoregulatory sweat collected throughout. V˙O2peak peak power output (PPO)...
The aim of this study was to determine the anthropometric and physiological profile 200-m sprint kayakers examine relationships with race performance. Twenty-six male who were categorised in two ability groups, international (Int) national (Nat) level, underwent a battery tests race. Race time significantly lower Int than Nat (39.9 +/- 0.8 s 42.6 0.9 s, respectively). demonstrated greater measures mesomorphy, biepycondylar humeral breadth, circumferences upper arm, forearm chest, peak power...
To determine the relative importance of anthropometric and physiological attributes for performance in 1000-m, 500-m, 200-m flatwater kayaking events.Eighteen competitive male kayakers completed trials over 3 distances a battery tests.Performance times (mean +/- SD) 1000 m, 500 200 m were 262.56 36.44 s, 122.10 5.74 41.59 2.12 respectively. Performance all events was correlated with number parameters; addition, 500-m upper body dimensions. 1000-m time predicted by power output at lactate...
Compression garments are frequently used to facilitate recovery from strenuous exercise.To identify the effects of 2 different grades compression garment on indices after exercise.Forty-five recreationally active participants (n = 26 male and n 19 female) completed an eccentric-exercise protocol consisting 100 drop jumps, which they were matched for body mass randomly but equally assigned a high-compression pressure (HI) group, low-compression (LOW) or sham ultrasound group (SHAM)....
Exercise-induced laryngeal obstruction (EILO) is a key differential diagnosis for respiratory symptoms in athletes and particularly prevalent aquatic athletes. A definitive of EILO dependent on laryngoscopy, performed continuously, while an athlete engages the sport that precipitates their symptoms. This report provides first description feasibility performing continuous laryngoscopy during exercise swimming environment. The describes methodology safety use swimming. Laryngoscope,...
During adolescence, an adequate diet is needed to fuel performance and support growth development. While many factors may impact dietary practices, there are some positive associations between nutritional knowledge (NK) intake. Understanding levels of NK a key aspect in improving athletic performance. The aims this research were evaluate the adolescent Ladies Gaelic Football (LGF) players determine whether any differences age groups competitive level. One hundred seven LGF completed abridged...