A5082744662- Hepatitis B Virus Studies
- Respiratory viral infections research
- Influenza Virus Research Studies
- T-cell and B-cell Immunology
- COVID-19 Clinical Research Studies
- Immune Cell Function and Interaction
- vaccines and immunoinformatics approaches
- Immunotherapy and Immune Responses
- Pneumonia and Respiratory Infections
- Viral Infections and Outbreaks Research
- Cancer Immunotherapy and Biomarkers
- SARS-CoV-2 and COVID-19 Research
Huashan Hospital
2023-2025
Fudan University
2023-2025
Abstract Inactivated coronavirus disease 2019 (COVID-19) vaccines and receptor binding domain subunit (RBD-subunit) booster vaccination can induce effective humoral immune response. CD4+ T helper cells are essential in helping B antibody However, the response of to vaccination, especially virus-induced follicular (Tfh) cells, needs be better characterized. In this study, it was investigated using tools single-cell sequencing flow cytometry. Additionally, a customized analysis algorithm...
BackgroundSeveral respiratory infections outbreaks have been observed in mainland China after reduction of non-pharmaceutical interventions. Other countries seen increases outside typical seasons post-COVID-19, warranting investigation into underlying causes.MethodsWe established monitoring networks for suspected infection 14 tertiary hospitals nationwide. PCR SARS-CoV-2, influenza A and B were performed on 3708 specimens deep sequencing conducted to identify co-infections or newly emerging...
The understanding of dynamic plasma proteome features in hybrid immunity and breakthrough infection is limited. A deeper the immune differences between heterologous homologous immunization could assist future establishment vaccination strategies. In this study, 40 participants who received a third dose either BBIBP-CorV or ZF2001 protein subunit vaccine following two doses inactivated coronavirus disease 2019 vaccines 12 patients with BA2.2 infections were enrolled. Serum samples collected...