A5008193884- Nanoparticles: synthesis and applications
- Graphene and Nanomaterials Applications
- Computational Drug Discovery Methods
- Advanced Nanomaterials in Catalysis
- Graphene research and applications
- Nanoparticle-Based Drug Delivery
- SARS-CoV-2 and COVID-19 Research
- 2D Materials and Applications
- Advanced biosensing and bioanalysis techniques
- MXene and MAX Phase Materials
- Acute Myeloid Leukemia Research
- Alzheimer's disease research and treatments
- Bacteriophages and microbial interactions
- Environmental Toxicology and Ecotoxicology
- Advancements in Battery Materials
- vaccines and immunoinformatics approaches
- CRISPR and Genetic Engineering
- Bacterial biofilms and quorum sensing
- Medicinal Plants and Neuroprotection
- Protein Structure and Dynamics
- Machine Learning in Bioinformatics
- Cancer-related molecular mechanisms research
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Salmonella and Campylobacter epidemiology
Uppsala University
2019-2024
KIIT University
2017-2023
Karolinska Institutet
2022-2023
University of Southern Denmark
2023
University of Freiburg
2017-2021
Indian Institute of Technology Bhubaneswar
2021
University Medical Center Freiburg
2018-2021
University of Lucknow
2020
D.Y. Patil University
2015-2018
Society of Paediatric Oncology and Haematology
2018
We report development of in-silico approaches for the identification anti-coronaviral drugs against SARS-CoV-2.
As bioapplications of 0D and 1D zinc oxide (ZnO) seem a recent development, they have brought many exciting proposals showing exquisite signs as sensors assay platforms offering biomolecular selectivity sensitivity for cancer diagnosis treatment. Cancer researchers are looking diagnostic molecular instruments to identify the cancer-causing agents subtle shifts. The inclusion high-performance ZnO materials due their intrinsic properties such viability, bio-acceptability, high isoelectric...
Over the years, seaweeds have been highlighted as valuable natural sources of bioactive polysaccharides. Fucoidan, a sulphated polysaccharide mainly from brown composed fucopyranose backbone and several monosaccharides, reported to possess numerous biological activities such anticancer, antioxidant, immunoregulatory, antiviral, antithrombic, anti-inflammatory properties thus may confer health benefits humans. However, main mechanisms bridging structural complexity fucoidans their activity...
Zinc oxide nanomaterials have been the cynosure of this decade because their immense potential in different biomedical applications. It includes usage prognosis and treatment infectious cellular diseases, owing to peculiar physiochemical properties such as variable shape, size, surface charge etc. Increasing demand ZnO raise concerns about molecular toxicity biocompatibility with human cells. This review comprehensively details for Furthermore, toxicological types systems reviewed. Moreover,...
The aggrandised advancement in utility of advanced day-to-day materials and nanomaterials has raised serious concern on their biocompatibility with human other biotic members. In last few decades, understanding toxicity these been given the centre stage research using many vitro vivo models. Zebrafish (Danio rerio), a freshwater fish member minnow family garnered much attention due to its distinct features, which make it an important frequently used animal model various fields embryology...
With the rapid development of nanotechnology, much has been anticipated with copper oxide nanoparticles (CuO NP) due to their extensive industrial and commercial application. However, it raised concern over environmental safety human health effects. In this study, CuO were synthesized using green method floral extract Calotropis gigantea characterized by standard physiochemical techniques like DLS, Zeta potential determination, UV- Visible Spectroscopy, XRD, FTIR, FESEM, TEM. Mechanistic...
Abstract The design and synthesis of a necklace‐like nitrogen‐doped tubular carbon (NTC) are presented by growing microporous polyhedral ZIF‐8 particles uniform layer on sacrificial ZnO tetrapods (ZTPs). Oxygen vacancies together with defect regions the surface ZTPs result in formation polyhedra conjunction very thin shell. This NTC structure has high N content, large area, ultrahigh microporosity, quite electrical conductivity. NTC‐based symmetrical supercapacitor zinc‐ion capacitor (ZIC)...
This study investigates the in vivo cytotoxicity of ZnO nanoparticles synthesized at industrial scale with embryonic Zebrafish. Industrial synthesis was mimicked lab by high energy ball milling technique bulk particles for 15 h. Synthesized 7 h and 10 showed significant alteration size, zeta potential optical properties comparison to Bulk ZnO. Mortality hatching rate Zebrafish embryos were influenced these alterations. Size charge dependent effect exposure on physiology development evident...
To investigate molecular aspects of the antibacterial effect size-dependent core-shell intrinsic defects nanocrystalline ZnO synthesized through high energy ball milling technique.Mechanically and characterized 7, 10 15 h milled nanoparticles were evaluated for activity with investigation by computational docking.Synthesized displayed shrinkage core increase shell reduction in size bulk particles from 250 to 80, 40 20 nm zeta potential up -19 mV nano ZnO. Antibacterial was found increased...
Immune evasion is one of the unique characteristics severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) attributed to its ORF8 protein. This protein modulates adaptive host immunity through down-regulation MHC-1 (Major Histocompatibility Complex) molecules and innate immune responses by surpassing host's interferon-mediated antiviral response. To understand perspective in reference protein, a comprehensive study mutations possessed it have been performed. Chemical structural...
An in-depth understanding of the practical sensing mechanism two-dimensional (2D) materials is critically important for design efficient nanosensors toward environmentally toxic gases. Here, we have performed van der Waals-corrected density functional theory (DFT) simulations along with nonequilibrium Green's function (NEGF) to investigate structural, electronic, transport, thermodynamic, and gas-sensing properties pristine defect-crafted bismuthene (bBi) sheets sulfur- (H2S, SO2)...
Rapid biosynthesis of silver nanoparticles from Gram +ve and −ve bacterial strains their hiogenicity dependent antibacterial cytntoxicity.
Thermodynamics and electronic investigations of Li/Na-functionalized BP monolayer reveals that it may operate as an attractive basis material for hydrogen storage applications.