Xuejian Hou

ORCID: 0000-0003-4880-9055
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About
Contact & Profiles
Research Areas
  • Cardiac and Coronary Surgery Techniques
  • Acute Kidney Injury Research
  • Coronary Interventions and Diagnostics
  • Acute Myocardial Infarction Research
  • Cardiac Arrest and Resuscitation
  • Cardiac Valve Diseases and Treatments
  • Cardiac Imaging and Diagnostics
  • Mechanical Circulatory Support Devices
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Cardiovascular Function and Risk Factors
  • Reconstructive Surgery and Microvascular Techniques
  • Cell death mechanisms and regulation
  • Chronic Kidney Disease and Diabetes
  • Metabolism, Diabetes, and Cancer
  • Autophagy in Disease and Therapy
  • Electrospun Nanofibers in Biomedical Applications
  • Cardiovascular Disease and Adiposity
  • Cardiac Ischemia and Reperfusion
  • Atrial Fibrillation Management and Outcomes
  • Renal and Vascular Pathologies

Beijing Anzhen Hospital
2018-2025

Capital Medical University
2018-2025

Capital University
2020

ORCID
2020

Acute kidney injury (AKI) is a common and serious complication after coronary artery bypass grafting (CABG), significantly affecting patient outcomes. The triglyceride-glucose (TyG) index, marker of insulin resistance, has shown potential in predicting various metabolic cardiovascular conditions. This study aimed to evaluate the predictive value TyG index for AKI occurrence following CABG. retrospective, single-center included 3,260 patients who underwent Patients were categorized into...

10.1186/s12872-025-04584-0 article EN cc-by-nc-nd BMC Cardiovascular Disorders 2025-03-21

This study was designed to explore the protective effect of 2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucoside (TSG) against ischemia/reperfusion (I/R) injury-induced cardiomyocytes apoptosis.The H9c2 cell I/R injury model induced by simultaneous shortage nutrients and oxygen. TSG administration (0.10, 0.25, 0.50 mM) performed before during stimulation. Cell apoptosis evaluated using terminal deoxynucleotidyl transferase dUTP nick end labeling assay. Expression cell-related proteins detected...

10.1002/jcb.27949 article EN Journal of Cellular Biochemistry 2019-03-19

Background: The incidence of postoperative acute kidney injury (AKI) is high due to insufficient perfusion in patients with heart failure. Heart failure preserved ejection fraction (HFpEF) have strong heterogeneity, which can obtain more accurate results. There are few studies for predicting AKI after coronary artery bypass grafting (CABG) HFpEF especially using machine learning methodology. Methods: Patients were recruited this study from 2018 2022. was defined according the Kidney Disease...

10.31083/j.rcm2502043 article EN cc-by Reviews in Cardiovascular Medicine 2024-01-29

To compare the long-term outcomes of coronary artery bypass grafting (CABG) vs. percutaneous intervention (PCI) with drug-eluting stents (DESs) for disease (CAD) patients chronic kidney (CKD).Coronary decreased function (estimated glomerular filtration rate <60 ml/min/1.73 m2) who underwent CABG (n = 533) or PCI DES 952) from 2013 to 2020 were enrolled at a single center. The baseline characteristics and clinical compared between groups each matched pair CKD. primary endpoint was occurrence...

10.3389/fcvm.2022.802181 article EN cc-by Frontiers in Cardiovascular Medicine 2022-04-01

Acute kidney injury (AKI) after coronary artery bypass graft (CABG) surgery is associated with significant morbidity and mortality. This retrospective study aimed to establish a risk score for postoperative AKI in Chinese population.A total of 1138 patients undergoing CABG were collected from September 2018 May 2020 divided into derivation validation cohort. was defined according the Kidney Disease Improving Global Outcomes (KDIGO) criteria. Multivariable logistic regression analysis used...

10.11909/j.issn.1671-5411.2021.09.011 article EN PubMed 2021-09-28

In the mid-1990s, Swedish expert team proposed saphenous vein graft (SVG) harvesting with pedicle tissue. The short-term and long-term patency rates of great obtained by no-touch (NT) were higher than those conventional (CON). past, NT was mainly used in on-pump coronary artery bypass grafting (CABG), grafts mostly single grafts. this study, we retrospectively analyzed safety effectiveness sequential using off-pump CABG.From 2017 to 2019, a total 505 patients included study. There 150 group...

10.3389/fcvm.2021.804739 article EN cc-by Frontiers in Cardiovascular Medicine 2022-01-24

Objectives Aims to compare the contemporary and long-term outcomes of coronary artery bypass grafting (CABG) percutaneous intervention (PCI) in disease (CAD) patients with advanced chronic kidney (CKD). Methods 823 CAD CKD (eGFR &amp;lt; 30 ml/min/1.73 m 2 ) were collected, including 247 who underwent CABG 576 received PCI from January 2014 February 2021. The primary endpoint was all-cause death. secondary endpoints included major adverse cardiac cerebrovascular events (MACCEs), myocardial...

10.3389/fsurg.2022.1042186 article EN cc-by Frontiers in Surgery 2023-01-20

Background and Aim of the Study Many studies support that no-touch (NT) procedure can improve patency rate vein grafts. However, it is not clear sequential graft early expansion in NT technique during off-pump coronary artery bypass grafting (CABG). This study will explore this issue. Methods was a prospective single-center randomized controlled clinical trial. A total 100 patients undergoing CABG with saphenous were randomly assigned to two groups: conventional (CON) groups. Perioperative...

10.1111/jocs.15577 article EN Journal of Cardiac Surgery 2021-05-07

Despite its limitations, unfractionated heparin (UFH) has been the standard anticoagulant used during percutaneous coronary intervention (PCI). This study compared safety of low-dose UFH with sequential enoxaparin that in patients diabetes mellitus (DM) and complex artery disease receiving elective PCI.In this retrospective study, 514 consecutive atherosclerotic cardiovascular diseases type 2 DM were admitted to hospital received selective PCI, from January 2013 December 2015. All PCI...

10.4103/0366-6999.228251 article EN cc-by-nc-nd Chinese Medical Journal 2018-03-22

Objective To evaluate the safety and cost of early discharge compared with ordinary in patients diabetes mellitus (DM) following percutaneous coronary intervention (PCI) for acute syndrome. Methods We performed a retrospective analysis prospectively collected data from 474 DM who were discharged hospital PCI at regional center between 2012 2015. Results A total 192 (40.5%) included group 282 (59.5%) group. Mortality morbidity after recorded. Kaplan–Meier showed similar prognosis two groups...

10.1177/0300060519842777 article EN cc-by-nc Journal of International Medical Research 2019-06-13

Abstract Objectives Aims to compare the contemporary and long-term outcomes of coronary artery bypass grafting (CABG) percutaneous intervention (PCI) in disease (CAD) patients with advanced chronic kidney (CKD). Design Observational cohort study, single-center. Setting The largest cardiac surgery center China. Participants 823 CAD CKD (eGFR&lt;30 ml/min/1.73m 2 ) were collected, including 247 who underwent CABG 576 received PCI from January 2010 February 2019. Main outcome measures primary...

10.21203/rs.3.rs-92124/v1 preprint EN cc-by Research Square (Research Square) 2020-10-16

Abstract Background: Elderly patients are more likely to have adverse complications after coronary artery bypass grafting (CABG). There few studies on the risk factors of acute kidney injury (AKI) surgery in elderly patients, especially Asian population. This study retrospectively analyse AKI Chinese CABG, and establish a prediction model detect these early take active intervention measures. Methods: A total 432 were included this from 2018 2019. was defined according Kidney Disease...

10.21203/rs.3.rs-119398/v1 preprint EN cc-by Research Square (Research Square) 2020-12-10

Abstract Background: Coronary artery bypass grafting (CABG) materials comprise the combination of left internal mammary and saphenous vein. The patency rate vein grafts is considered not ideal; more studies support that no-touch (NT) procedure can improve grafts. However, it clear NT technology used in sequential during off-pump coronary surgery. This study explored whether technique safety efficacy compared to conventional manner surgery using graft. Methods: was a prospective single-center...

10.21203/rs.3.rs-78252/v1 preprint EN cc-by Research Square (Research Square) 2020-09-23

Background and aim of the study: Elderly patients are more likely to have adverse complications after coronary artery bypass grafting (CABG). There few studies on risk factors for acute kidney injury (AKI) surgery in elderly patients, especially Asian population. This study retrospectively analysed AKI Chinese CABG established a prediction model detect these early take active intervention measures. Methods: A total 432 were included this from 2018 2019. was defined according Kidney Disease...

10.22541/au.161399701.10586159/v1 preprint EN Authorea (Authorea) 2021-02-22

Abstract Background: The main graft material for coronary artery bypass grafting (CABG) is the combination of internal mammary and great saphenous vein. patency rate vein grafts considered not ideal; more studies support that no-touch (NT) procedure can improve grafts. However, it clear NT technology used in sequential during off-pump surgery. This study explored whether technique as safe effective conventional surgery using Methods: was a prospective single-centre randomized controlled...

10.21203/rs.3.rs-151059/v1 preprint EN cc-by Research Square (Research Square) 2021-01-22

Abstract Background In the mid-1990s, Swedish expert team proposed saphenous vein graft (SVG) harvesting with pedicle tissue. The short-term and long-term patency rates of great obtained by no-touch technique (NT) were higher than those conventional (CON). past, NT technology was mainly used in on-pump coronary artery bypass grafting (CABG), grafts mostly single grafts. this study, we retrospectively analysed safety effectiveness sequential using off-pump CABG. Methods From 2017 to 2019, a...

10.21203/rs.3.rs-155554/v1 preprint EN cc-by Research Square (Research Square) 2021-02-02
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