A5009958972- Breast Cancer Treatment Studies
- Global Cancer Incidence and Screening
- Economic and Financial Impacts of Cancer
- Breast Lesions and Carcinomas
- Health Systems, Economic Evaluations, Quality of Life
- Breast Implant and Reconstruction
- HER2/EGFR in Cancer Research
- Digital Radiography and Breast Imaging
- Reconstructive Surgery and Microvascular Techniques
- Patient-Provider Communication in Healthcare
- Body Contouring and Surgery
- AI in cancer detection
- Diversity and Career in Medicine
- Advanced Breast Cancer Therapies
- Biomedical and Engineering Education
- Cervical Cancer and HPV Research
- Health and Medical Research Impacts
- Statistical Methods in Clinical Trials
- Palliative Care and End-of-Life Issues
- Opioid Use Disorder Treatment
- Anesthesia and Pain Management
- Surgical site infection prevention
- Cancer survivorship and care
- BRCA gene mutations in cancer
- Cancer Treatment and Pharmacology
The University of Texas MD Anderson Cancer Center
2018-2024
Johns Hopkins Medicine
2022
Johns Hopkins Hospital
2022
Johns Hopkins University
2022
Harvard University
2022
The Ohio State University Wexner Medical Center
2018-2019
NYU Langone Health
2009-2012
The Relationship of Mammographic Density and Age: Implications for Breast Cancer ScreeningCristina M. Checka1, Jennifer E. Chun1, Freya R. Schnabel1, Jiyon Lee2 Hildegard Toth2Audio Available | Share
Abstract Background Traditional 2-stage breast reconstruction involves placement of a textured-surface tissue expander (TTE). Recent studies have demonstrated textured surface devices higher propensity for bacterial contamination and biofilm formation. Objectives The purpose this study was to evaluate the safety efficacy smooth expanders (STE) in immediate reconstruction. Methods authors retrospectively reviewed consecutive women who underwent STE from 2016 2017 at 3 institutions....
Abstract Background Patients with triple-negative breast cancer (TNBC) and a pathological complete response (pCR) after neoadjuvant chemotherapy may be suitable for non-surgical management. The goal of this study was to identify baseline clinicopathological variables that are associated residual disease, evaluate the effect on both invasive ductal carcinoma in situ (DCIS) components TNBC. Methods TNBC treated followed by surgical resection were identified. pCR compared those who had disease...
PURPOSE: Patients with cancer frequently encounter financial hardship, yet systematic strategies to identify at-risk patients are not established in care delivery. We assessed sensitivity of distress-based screening cancer-related hardship and associated delivery outcomes. METHODS: A survey 225 at a large center (0-10 Likert scale; highest quintile scores ≥ 5 defined severe hardship). Responses were linked electronic medical records identifying patients’ distress 6 months presurvey scale)...
Objectives This study sought to evaluate advanced psychometric properties of the 15-item Economic Strain and Resilience in Cancer (ENRICh) measure financial toxicity for cancer patients. Methods We surveyed 515 patients greater Houston metropolitan area using ENRICh from March 2019 2020. conducted a series factor analyses alongside parametric non-parametric item response theory (IRT) assessments Mokken analysis graded model (GRM). utilized parameters derived GRM run simulated computerized...
To evaluate the acceptability and impact of 3D-printed breast models (3D-BMs) on treatment-related decisional conflict (DC) cancer patients.Patients with were accrued in a prospective institutional review board-approved trial. All patients underwent contrast-enhanced magnetic resonance imaging (MRI). A personalized 3D-BM was derived from MRI. DC evaluated pre- post-3D-BM review. assessed review.DC surveys before after completed by 25 patients. generated two bilateral cancer. The mean patient...
153 Background: Financial toxicity is a patient-reported outcome reflecting burdens of cancer treatment costs. There need to assess financial in care, as its unique domains—upstream factors like direct medical costs or downstream economic impact bankruptcy—predict worse QOL, adherence, and mortality. Socioeconomically disadvantaged patients bear disparate burdens. We thus developed report performance new measure, the Economic StraiN Resilience Cancer (ENRICh), all domains economically...
Abstract Background: The addition of trastuzumab+/-pertuzumab to chemotherapy has changed the natural history earlyHER2+ breast cancer. However, trials with targeted therapy alone are needed avoid acute and chronic toxicities chemotherapy. Zanidatamab is a novel, humanized, bispecific, immunoglobulin G isotype 1-like, monoclonal antibody directed against juxtamembrane extracellular dimerization domains (ECD2, ECD4) HER2. biparatopic nature zanidatamab results in HER2 clustering that...
Background: The low uptake of antiestrogen preventive therapy among women at high risk developing breast cancer remains a challenge. We implemented performance improvement program to increase the with atypical hyperplasia (AH) and lobular in situ (LCIS).Methods: A was MD Anderson Cancer Center (Houston, TX), November 2015 February 2017, for patients new (<6 months) or existing (≥6 diagnosis AH/LCIS. consisted an audit eligible who were recommended prescribed provision clinical feedback...
Outcome of patients (pts) w/ stage I node neg HER2+ treated wkly paclitaxel x 12 doses and trastuzumab 1yr is excellent (10yr RFS 96%). Therefore, trials to de-escalate chemo use targeted therapy alone are underway. Zanidatamab a novel, humanized, bispecific, immunoglobulin G isotype 1-like, monoclonal antibody directed against the juxtamembrane extracellular domain (ECD4) dimerization (ECD2) HER2. This results in HER2 clustering that modulates signaling leads immune activation. demonstrated...
Abstract Previous studies have demonstrated that use of chaperones by physicians occurs most consistently for pelvic and rectal exams than breast examinations. Factors may influence chaperone examination include duration doctor-patient relationship, gender the examiner, availability an assistant. The purpose this study is to characterize patient preferences, not previously reported, use.A questionnaire was approved institutional IRB at NYU Langone Medical Center Bellevue Hospital. It...
Abstract Background: Mammographic density generally decreases over time, which increases the sensitivity of screening mammography. However a significant proportion older women have persistently dense breast tissue. This raises question how best to screen women, particularly those with mammographically tissue or other risk factors. Little information exists about accuracy mammography in than seventy years. Additionally, frequency mammographically-occult cancer is also unknown. The purpose...
1598 Background: Recent recommendations by the U.S. Preventive Services Task Force were based on population-based studies and meta-analyses that did not specifically address minority women. A recognized disparity in health care delivery is underutilization of screening services patients. The purpose this study was to characterize clinico-pathologic features multi-ethnic breast cancer patients at an urban tertiary hospital who would be screened under these new guidelines. Methods:...
Introduction. Elucent Medical has introduced a novel EnVisio™ Surgical Navigation system which uses SmartClips™ that generate unique electromagnetic signal triangulated in 3 dimensions for real-time navigation. The purpose of this study was to evaluate the efficacy and feasibility EnVisio localizing excising nonpalpable lesions breast axillary surgery. Methods. This pilot prospectively examined patients undergoing nodal localization using system. SmartClips were placed by designated...
Abstract Mammographic density has been established as an independent risk factor for breast cancer, and there is data to suggest that the degree of lobular involution in tissue may also function disease. The present study was designed investigate relationship between mammographic a population mature women undergoing open biopsy non-palpable lesions.A total 199 over age 60 who underwent with image-guided localization 2008 at NYU Langone Medical Center formed population. Variables interest...
e11064 Background: We demonstrated in three prospective trials that taxane-based concurrent chemo-radiation achieves high pathological response rates correlate with decreased recurrence and improved survival locally advanced breast cancers (LABC, Adams et al, BCRT 2010). now report the results among HER-2 positive LABC patients treated trastuzumab paclitaxel radiotherapy, preoperatively. Methods: Patients (stages IIB-IIIC) were prospectively as part of an IRB-approved neoadjuvant...
e18799 Background: Post-operative analgesia requirements vary, but no guidelines exist for opioid prescription (Rx) after breast surgical oncology (BSO) procedures. Given the national epidemic, we sought to characterize prescribing and patterns of use in a large academic BSO practice. Methods: Consecutive patients (n = 253) undergoing operation from November 13, 2017 January 12, 2018 at cancer center were surveyed 1 week post-operatively number pills used. Surgeons 17) about pain management...
Park, Ko Un MD; Clemens, Mark W. MD, FACS; Lange, Caitlin E. PA-C; Bridges, Christian A. Checka, Cristina M. MD Author Information