Mediget Teshome

ORCID: 0000-0001-8632-0256
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About
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Research Areas
  • Breast Cancer Treatment Studies
  • Breast Lesions and Carcinomas
  • HER2/EGFR in Cancer Research
  • Cancer Treatment and Pharmacology
  • Breast Implant and Reconstruction
  • Cancer Genomics and Diagnostics
  • Advanced Breast Cancer Therapies
  • Global Cancer Incidence and Screening
  • Colorectal Cancer Surgical Treatments
  • Diversity and Career in Medicine
  • Cancer Diagnosis and Treatment
  • Cancer Cells and Metastasis
  • Clinical practice guidelines implementation
  • Economic and Financial Impacts of Cancer
  • Advances in Oncology and Radiotherapy
  • Brain Metastases and Treatment
  • Dental Education, Practice, Research
  • Multiple and Secondary Primary Cancers
  • Surgical Simulation and Training
  • BRCA gene mutations in cancer
  • Gastric Cancer Management and Outcomes
  • Cardiac, Anesthesia and Surgical Outcomes
  • Single-cell and spatial transcriptomics
  • MRI in cancer diagnosis
  • Cancer survivorship and care

The University of Texas MD Anderson Cancer Center
2016-2025

University of California, Los Angeles
2024-2025

UCLA Health
2024-2025

Jimma University
2025

UCLA Jonsson Comprehensive Cancer Center
2025

Northwestern University
2023-2024

UCLA Medical Center
2024

Breast Cancer Care
2024

Northeast Georgia Medical Center
2024

University of Southern California
2023

<h3>Importance</h3> A pathologic complete response (pCR; no invasive or in situ cancer) occurs 40% to 50% of patients with<i>HER2</i>-positive (<i>HER2</i>+) and triple-negative (TN) breast cancer. The need for surgery if percutaneous biopsy the after neoadjuvant chemotherapy (NCT) indicates pCR (hereinafter referred as pCR) has been questioned, appropriate management axilla such is unknown. <h3>Objective</h3> To identify among exceptional responders NCT with a low risk axillary metastases...

10.1001/jamasurg.2017.0562 article EN JAMA Surgery 2017-04-19

Objective: To determine the accuracy of fine-needle aspiration (FNA) and vacuum-assisted core biopsy (VACB) in assessing presence residual cancer breast after neoadjuvant systemic therapy (NST). Summary Background Data: Pathologic complete response (pCR) rates NST have improved dramatically, suggesting that surgery might be avoided some patients. Safe avoidance would require accurate confirmation no invasive/in situ carcinoma. Methods: Forty patients with T1-3N0-3 triple-negative or...

10.1097/sla.0000000000002313 article EN Annals of Surgery 2017-05-26

National and international experts in inflammatory breast cancer (IBC) from high-volume centers treating IBC recently convened at the 10th Anniversary Conference of Morgan Welch Inflammatory Breast Cancer Research Program The University Texas MD Anderson Center Houston Texas. A consensus on clinical management patients with was discussed, summarized, subsequently reviewed. All participants conference (patients, advocates, researchers, trainees, clinicians) were queried using MDRing...

10.7150/jca.23969 article EN cc-by-nc Journal of Cancer 2018-01-01

Importance Neoadjuvant systemic therapy (NST) has been associated with pathologic complete response (pCR) in up to 60% of breast cancers (BCs). The findings this trial question the necessity surgery. Objective To report preplanned 5-year efficacy outcomes evaluating radiotherapy alone without surgery patients selected image-guided vacuum assisted biopsy (VAB). Design, Setting, and Participants This single-arm, prospective, phase 2 nonrandomized clinical was conducted at 7 US medical centers...

10.1001/jamaoncol.2025.0207 article EN JAMA Oncology 2025-03-28

Abstract Background: Increasing use of NCT regimens and improved selection appropriate candidates has increased rates pCR raised the question whether surgical removal primary tumor is required for these patients (pts). To avoid surgery, ability to predict after must be very accurate. Breast imaging alone (even when it includes mammogram, ultrasound, breast MRI), inadequate achieve this. We hypothesized that performing core needle biopsy (bx) bed in addition tri-modality pts who have clinical...

10.1158/1538-7445.sabcs19-gs5-05 article EN Cancer Research 2020-02-15

Objective: To summarize the multi-specialty strategy and initial guidelines of a Case Review Committee in triaging oncologic surgery procedures large Comprehensive Cancer Center to outline current steps moving forward after wave. Summary Background Data: The impetus for strategic rescheduling operations is multifactorial includes our societal responsibility minimize COVID-19 exposure risk propagation among patients, healthcare workforce, community at large. Strategic also driven by need...

10.1097/sla.0000000000004092 article EN Annals of Surgery 2020-05-18

Objective: A prospective, phase IV study was conducted to assess the effectiveness of Magseed localize breast lesions requiring surgical excision. Background: Since Food and Drug Administration approval in 2016, has been increasingly used nonpalpable due advantages over wires or radioactive seeds. This is first postmarketing trial Magseed. Methods: From January 2017 February 2018, 107 women with localization were enrolled at a single institution. Primary endpoint retrieval rate. Secondary...

10.1097/as9.0000000000000008 article EN cc-by-nc-nd Annals of Surgery Open 2020-09-01
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