A5068862432- Legionella and Acanthamoeba research
- Vibrio bacteria research studies
- Bacterial biofilms and quorum sensing
- Water Treatment and Disinfection
- Plant-Microbe Interactions and Immunity
- Plant Pathogens and Resistance
- Plant Disease Resistance and Genetics
University of Michigan
2019
Purdue University West Lafayette
2014
Phytophthora root and stem rot (PRR) of soybean, caused by sojae, is controlled Rps genes. However, little known regarding the Rps-induced molecular responses to P. sojae how they actually overlap. We thus sequenced, analyzed, compared transcriptomes 10 near isogenic lines (NILs), each with a unique gene/allele, susceptible parent Williams, pre- post-inoculation pathogen. A total 4,330 differentially expressed genes (DEGs) were identified in Williams versus 2,014 5,499 DEGs individual NILs...
Although an intracellular pathogen, L. pneumophila has developed mechanisms to ensure long-term survival in low-nutrient aqueous conditions. Eradication of from contaminated water supplies proven challenging, as outbreaks have been traced previously remediated systems. Understanding the genetic determinants that support persistence environments can inform design and assessment remediation strategies. Here we characterize a locus encodes two-component signaling system ( lpg0278-lpg0277 )...
Communities of bacteria that cause Legionnaires' disease repel other by secreting an acid called HGA
ABSTRACT During its life cycle, the environmental pathogen Legionella pneumophila alternates between a replicative and transmissive cell type when cultured in broth, macrophages, or amoebae. Within protozoan host, L. further differentiates into hardy known as Mature Infectious Form (MIF). The second messenger cyclic-di-GMP coordinates lifestyle changes many bacterial species, but role cycle is less understood. Using an vitro broth culture model that approximates intracellular transition from...