Feng Lin

ORCID: 0000-0001-7491-4444
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About
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Research Areas
  • Plant Disease Resistance and Genetics
  • Soybean genetics and cultivation
  • Plant Pathogens and Resistance
  • Legume Nitrogen Fixing Symbiosis
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Liver Disease Diagnosis and Treatment
  • Plant Pathogens and Fungal Diseases
  • Plant-Microbe Interactions and Immunity
  • Plant Virus Research Studies
  • Genetic Mapping and Diversity in Plants and Animals
  • Influenza Virus Research Studies
  • Genetic and Environmental Crop Studies
  • Cancer-related molecular mechanisms research
  • Immunotherapy and Immune Responses
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Cancer Immunotherapy and Biomarkers
  • Nematode management and characterization studies
  • Long-Term Effects of COVID-19
  • Chromosomal and Genetic Variations
  • Cancer Diagnosis and Treatment
  • Plant Pathogenic Bacteria Studies
  • Wheat and Barley Genetics and Pathology
  • Crustacean biology and ecology
  • Inhalation and Respiratory Drug Delivery

Delta Air Lines (United States)
2024-2025

University of Missouri
2024-2025

University of Hong Kong - Shenzhen Hospital
2024-2025

University of Hong Kong
2024-2025

Michigan State University
2018-2024

Hainan General Hospital
2017-2024

Harbin Medical University
2016-2024

Second Affiliated Hospital of Harbin Medical University
2016-2024

Shanghai Jiao Tong University
2021-2022

Chinese PLA General Hospital
2021

Abstract Similar to Arabidopsis thaliana, the wild soybeans (Glycine soja) and many cultivars exhibit indeterminate stem growth specified by shoot identity gene Dt1, functional counterpart of TERMINAL FLOWER1 (TFL1). Mutations in TFL1 Dt1 both result apical meristem (SAM) switching from vegetative reproductive state initiate terminal flowering thus produce determinate stems. A second soybean (Dt2) regulating was identified, which, presence produces semideterminate plants with racemes similar...

10.1105/tpc.114.126938 article EN The Plant Cell 2014-07-01

Phytophthora root and stem rot (PRR) of soybean, caused by sojae, is controlled Rps genes. However, little known regarding the Rps-induced molecular responses to P. sojae how they actually overlap. We thus sequenced, analyzed, compared transcriptomes 10 near isogenic lines (NILs), each with a unique gene/allele, susceptible parent Williams, pre- post-inoculation pathogen. A total 4,330 differentially expressed genes (DEGs) were identified in Williams versus 2,014 5,499 DEGs individual NILs...

10.1186/1471-2164-15-18 article EN cc-by BMC Genomics 2014-01-10

As computer science progresses, neuromusculoskeletal models are increasingly applied in clinical settings, particularly when studying abnormal characteristics patients with cerebral palsy. Digital enable researchers and clinicians to gain a deeper understanding of movement mechanisms, providing additional insights for diagnosis treatment. While biomechanical simulation platforms like OpenSim offer standardized simulation, relying on generic healthy simulate movements palsy can lead...

10.1109/tnsre.2025.3544551 article EN cc-by IEEE Transactions on Neural Systems and Rehabilitation Engineering 2025-01-01

Sweetpotato (Ipomoea batatas (L.) Lam.) is the seventh most important crop in world and mainly cultivated for its underground storage root (SR). The genetic studies of this species have been hindered by a lack high-quality reference sequence due to complex genome structure. Diploid Ipomoea trifida closest relative putative progenitor sweetpotato, which considered model including genetic, cytological, physiological analyses.Here, we generated chromosome-scale SR-forming diploid I. var. Y22...

10.1186/s12870-019-1708-z article EN cc-by BMC Plant Biology 2019-04-01

Abstract Objective: We conducted this study to compare the efficacy and safety of entecavir tenofovir in treatment treatment-naïve HBV e antigen (HBeAg)-positive patients with chronic hepatitis B (CHB) for 144 weeks. Methods: A total 320 HBeAg-positive CHB who received randomly a single regimen either capsule (ETV) (n = 160) or disoproxil fumarate (TDF) weeks were consecutively enrolled from 14 tertiary hospitals university China between January 2012 December 2014. Results: Two groups showed...

10.1097/md.0000000000013983 article EN cc-by-nc Medicine 2019-01-01

Tenofovir alafenamide (TAF) has similar efficacy to tenofovir disoproxil fumarate (TDF) but with improved renal and bone safety in chronic hepatitis B patients studied outside of China. We report 3-year results from two phase 3 studies TAF China (Clinicaltrials.gov: NCT02836249 NCT02836236).Chinese e antigen (HBeAg)-positive -negative viremia elevated alanine aminotransferase were randomized 2:1 or TDF treatment groups treated a double-blind fashion for 144 weeks (3 years). Efficacy...

10.14218/jcth.2020.00145 article EN Journal of Clinical and Translational Hepatology 2021-04-28

Abstract A survey of grass species associated with Neotyphodium and Epichloë fungal endophytes was made in the permanent grasslands northern China. total 41 species, 56 sites 172 local populations were examined to reveal endophytic infection native grasses. Twenty‐five forty‐one grasses (proportionately 0·61) infected by endophytes: twenty‐two had a mean rate 0·01–0·50 only three >0·50. Of examined, however, proportionately 0·72 not infected, 0·181 an 0·099 0·51–1·00. Two genera grasses,...

10.1111/j.1365-2494.2006.00551.x article EN Grass and Forage Science 2006-12-01

We sampled five Achnatherum sibiricum populations and documented the distribution abundance of endophytes. In total, 438 fungal isolates were obtained. They classified into 11 morphotypes based on growth rate morphological characters including colonial morphology, production conidiogenous cells, conidial size dimension potato dextrose agar medium. Both tub2 actG sequences identified only a single product in all representative from three dominant morphotypes. All fell same main clade,...

10.1111/j.1574-6968.2009.01789.x article EN FEMS Microbiology Letters 2009-09-11

Recent sequencing of the Brassica rapa and oleracea genomes revealed extremely contrasting genomic features such as abundance distribution transposable elements between two genomes. However, whether how these structural differentiations may have influenced evolutionary rates since their split from a common ancestor are unknown. Here, we investigated compared nucleotide substitution long terminal repeats (LTRs) individual orthologous LTR-retrotransposons, synonymous non-synonymous among...

10.1111/tpj.12291 article EN The Plant Journal 2013-07-19

Disease-related genes, particularly the nucleotide binding site (NB)-leucine-rich repeat (LRR) class of R plant genes can be triggered by microRNAs (miRNAs) to generate phased small interfering RNAs (phasiRNAs), which could reduce transcript levels their targets. However, how global changes in NB-LRR coordinate with miRNA and phasiRNA defense responses remains largely unknown. Here, we investigated relative abundance (sRNAs), a focus on miRNAs phasiRNAs potential targets response pathogen...

10.3835/plantgenome2014.09.0044 article EN The Plant Genome 2015-02-06

Aconitum chasmanthum Stapf ex Holmes, a highly valued medicinal plant, is critically endangered plant species with restricted global distribution. Because there no published report on the in vitro micropropagation of A. chasmanthum, present study was undertaken to contribute development an efficient protocol for its conservation. Seeds collected from wild showed enhanced germination after being given chilling treatment (−4 °C and −20 °C) different durations (10, 20, 30 40 days). −4 10 days...

10.3390/horticulturae7120586 article EN cc-by Horticulturae 2021-12-17

Abstract Caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), disease 2019 (COVID‐19) primarily manifests as dysfunction. However, emerging evidence suggests SARS‐CoV‐2 can invade the brain, leading to cognitive impairment (CI). It may spread other brain regions through transsynaptic neurons, including olfactory, optic, and vagus nerves. Moreover, it central nervous system blood transmission or lymphatic system. This review summarizes neuroimaging from clinical imaging...

10.1002/brx2.58 article EN cc-by Brain‐X 2024-04-16

Phytophthora root rot, caused by oomycete pathogens in the genus, poses a significant threat to soybean productivity. While resistance mechanisms against sojae have been extensively studied soybean, molecular basis underlying immune responses sansomeana remains unclear. In this study, we investigated transcriptomic and epigenetic of two resistant (Colfax NE2701) susceptible (Williams 82 Senaki) lines at four time points (2, 4, 8, 16 h post inoculation [hpi]) after P. inoculation. Comparative...

10.1002/tpg2.20487 article EN cc-by-nc-nd The Plant Genome 2024-07-12

Abstract Pythium root rot is one of the significant diseases soybean (Glycine max (L.) Merr.) in United States. The causal agent disease a soil-borne oomycete pathogen irregulare, most prevalent and aggressive species North Central However, few studies have been conducted for identification quantitative trait loci (QTL) tolerance to P. irregulare. In this study, two recombinant inbred line (RIL) populations (designated as POP1 POP2) were challenged with irregulare (isolate CMISO2-5-14)...

10.1534/g3.118.200368 article EN cc-by G3 Genes Genomes Genetics 2018-10-01
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