A5037485998- Solar and Space Plasma Dynamics
- Ionosphere and magnetosphere dynamics
- Astro and Planetary Science
- Stellar, planetary, and galactic studies
- Geomagnetism and Paleomagnetism Studies
- Astrophysics and Star Formation Studies
- Gamma-ray bursts and supernovae
- Astrophysics and Cosmic Phenomena
- Geophysics and Gravity Measurements
- Astrophysical Phenomena and Observations
- Axon Guidance and Neuronal Signaling
- Astronomy and Astrophysical Research
- Neurogenesis and neuroplasticity mechanisms
- Magnetic confinement fusion research
- Plasma Diagnostics and Applications
- Pharmacy and Medical Practices
- Angiogenesis and VEGF in Cancer
- Heat Transfer Mechanisms
- Plasma Applications and Diagnostics
- Pulsars and Gravitational Waves Research
- Heat Transfer and Optimization
- Laser Design and Applications
- Hippo pathway signaling and YAP/TAZ
- Quantum, superfluid, helium dynamics
- Spectroscopy and Laser Applications
Tokyo University of Science
1997-2024
Osaka University
2012-2024
Ube Frontier University
2019-2024
National Institute of Biomedical Innovation, Health and Nutrition
2022-2024
National Institutes of Health
2011-2020
Japan Science and Technology Agency
2019
Centre for Research in Engineering Surface Technology
2019
The University of Tokyo
1993-2017
National Heart Lung and Blood Institute
2011-2017
Semiconductor Energy Laboratory (Japan)
2015-2017
Collapsin response mediating protein‐2 (CRMP2) has been identified as an intracellular protein Semaphorin3A (Sema3A), a repulsive guidance molecule. In this study, we demonstrate that cyclin‐dependent kinase 5 (Cdk5) and glycogen synthase 3β (GSK3β) plays critical role in Sema3A signalling. vitro assay, Cdk5 phosphorylated CRMP2 at Ser522, while GSK3β did not induce any phosphorylation of CRMP2. Phosphorylation by was exclusively observed Cdk5‐phosphorylated CRMP2, but barely CRMP2T509A....
A number of astronomical systems have been discovered that generate collimated flows plasma with velocities close to the speed light. In all cases, central object is probably a neutron star or black hole and either accreting material from other stars in initial violent stages formation. Supercomputer simulations production relativistic jets based on magnetohydrodynamic model, which differential rotation system creates magnetic coil simultaneously expels pinches some infalling material. The...
A member of semaphorin family, semaphorin3A (Sema3A), acts as a chemorepellent or chemoattractant on wide variety axons and dendrites in the development nervous systems. We here show that Sema3A induces clustering both postsynaptic density-95 (PSD-95) presynaptic synapsin I cultured cortical neurons without changing density spines filopodia. Neuropilin-1 (NRP-1), receptor for Sema3A, is present dendrites. When are exposed to cluster size PSD-95 markedly enhanced, an extensive colocalization...
view Abstract Citations (171) References (15) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Coronal heating by stochastic magnetic pumping Sturrock, P. A. ; Uchida, Y. Recent observational data cast serious doubt on the widely held that sun's corona is heated traveling waves (acoustic or magnetohydrodynamic). It here proposed energy responsible for derived from free of coronal field motion 'feet' lines in photosphere. Stochastic feet leads, average, to a...
Highlights•A portion of pericytes in the skin vasculature has a hematopoietic/myeloid origin•Depletion myeloid lineage causes defective pericyte development•TGF-β signaling controls differentiation progenitors to pericytesSummaryMural cells (pericytes and vascular smooth muscle cells) are essential for regulation networks maintenance integrity, but their origins diverse different tissues not known organs that arise from ectoderm, such as skin. Here, we show tissue-localized contribute...
Abstract Both in the Faraday Rotation Measure and intrinsic polarization angle, new features are revealed to indicate a helical magnetic field operating along jet of bright active galactic nucleus 3C 273. The has been suggested be related formation collimation jets by magnetohydrodynamic models. distribution rotation measure shows systematic gradient with respect axis, which is expected field. In addition, can consistently explain two types direction projected field: parallel perpendicular...
The Japanese Yohkoh satellite is now in orbit observing the sun with a set of x-ray imagers and gamma-ray spectrometers. data from this successful mission provide new information on solar flares sun's corona. This paper discusses observations presents sample first scientific results mission.
Collapsin response mediator protein 1 (CRMP1) is one of the CRMP family members that mediates signal transduction axonal guidance and neuronal migration. We show here evidence CRMP1 involved in semaphorin3A (Sema3A)-induced spine development cerebral cortex. In cultured cortical neurons from crmp1+/- mice, Sema3A increased density clusters synapsin I postsynaptic density-95, but this increase was markedly attenuated crmp1-/- mice. This attenuation also seen cyclin-dependent kinase 5...
Gli3, one of three vertebrate Gli transcription factors in Hedgehog (Hh) pathway, is processed into a repressor form (Gli3R) the absence Hh signal and acts as major negative transducer pathway. Although role Gli3 embryonic patterning has been extensively studied, its cortical neurogenesis, especially regulation neural progenitors proliferation cell fate specification, largely unknown. To bypass defects caused by loss we conditionally deleted after was complete mouse. Our results from...
Anatomical congruence of peripheral nerves and blood vessels is well recognized in a variety tissues. Their physical proximity similar branching patterns suggest that the development these networks might be coordinated process. Here we show large diameter coronary veins serve as an intermediate template for distal sympathetic axon extension subepicardial layer dorsal ventricular wall developing mouse heart. Vascular smooth muscle cells (VSMCs) associate with during angiogenesis. In vivo...
The lymphatic vasculature is essential for maintaining interstitial fluid homeostasis, and dysfunctional lymphangiogenesis contributes to various pathological processes, including inflammatory disease tumor metastasis. Mutations in FOXC2 are dominantly associated with late-onset lymphedema; however, the precise role of a closely related factor, FOXC1, system remains largely unknown. Here we identified molecular cascade by which FOXC1 regulate ERK signaling vessel growth. In mice, endothelial...
Abstract Alveolar macrophages (AMs) are crucial for maintaining normal lung function. They abundant in cancer tissues, but their pathophysiological significance remains unknown. Here we show, using an orthotopic murine model and human carcinoma samples, that AMs support cell proliferation thus contribute to unfavourable outcome. Inhibin beta A (INHBA) expression is upregulated under tumor-bearing conditions, leading the secretion of activin A, a homodimer INHBA. Accordingly, follistatin,...
view Abstract Citations (120) References (47) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Radio Jets and the Formation of Active Galaxies: Accretion Avalanches on Torus by Effect a Large-Scale Magnetic Field Matsumoto, R. ; Uchida, Y. Hirose, S. Shibata, K. Hayashi, M. Ferrari, A. Bodo, G. Norman, C. We present results 2.5-dimensional MHD simulations for magnetohydrodynamic model jet formation associated with active galaxies. also study enhanced accretion...
view Abstract Citations (122) References (33) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Morphology of Active Region Transient Brightenings with the YOHKOH Soft X-Ray Telescope Shimizu, Toshifumi ; Tsuneta, Saku Acton, Loren W. Lemen, James R. Ogawara, Yoshiaki Uchida, Yutaka Frequent transient X-ray brightenings occur in solar active regions. The Yohkoh observed 142 during an interval time late 1991 October. We classify them terms morphology and...