- Cancer Genomics and Diagnostics
- Molecular Biology Techniques and Applications
- T-cell and B-cell Immunology
- Thyroid Cancer Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Immune Cell Function and Interaction
- Cancer Immunotherapy and Biomarkers
- Cancer, Hypoxia, and Metabolism
- Colorectal Cancer Treatments and Studies
- Inflammatory Biomarkers in Disease Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Cytomegalovirus and herpesvirus research
- Cancer Cells and Metastasis
Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research
2021-2025
Universidad de Granada
2021-2023
In the tumor context, platelets play a significant role in primary progression, dissemination and metastasis. Analysis of this interaction various cancers, such as non-small cell lung cancer (NSCLC), demonstrate that can both transfer receive biomolecules (e.g. RNA proteins) to from at different stages, becoming tumor-educated platelets. To investigate how are able oncogenic material, we developed vitro platelet-like particles (PLPs), differentiated MEG-01 line, stably carry protein KRASG12D...
The isolation of circulating tumour cells (CTCs) in colorectal cancer (CRC) mostly relies on the expression epithelial markers such as EpCAM, and phenotypic characterisation is usually performed under fluorescence microscopy with only one or two additional markers. This limits ability to detect different CTC subpopulations based multiple aim this work was develop a novel protocol combining platforms (IsoFluxTM ImageStream®X) improve evaluation. Cancer cell lines peripheral blood from healthy...
Leishmaniasis is an infectious disease caused by protozoa of the genus Leishmania, which endemic in certain areas Europe, such as southern Spain. The manifests various clinical phenotypes, including visceral, cutaneous, mucosal, or asymptomatic leishmaniasis. This diversity outcomes may be influenced host immune response, with human leukocyte antigen (HLA) molecules playing a crucial role determining susceptibility and progression infection. study explores association between specific HLA...