A5073964868- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Non-Invasive Vital Sign Monitoring
- Cardiac Arrest and Resuscitation
- Renal function and acid-base balance
- Ultrasound in Clinical Applications
- Central Venous Catheters and Hemodialysis
- Emergency and Acute Care Studies
- Vascular Procedures and Complications
- Foreign Body Medical Cases
- Respiratory Support and Mechanisms
- Adrenal Hormones and Disorders
- Clinical Reasoning and Diagnostic Skills
- Gastrointestinal Tumor Research and Treatment
- Intensive Care Unit Cognitive Disorders
- Hematological disorders and diagnostics
- Healthcare Technology and Patient Monitoring
- Pneumocystis jirovecii pneumonia detection and treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Abdominal vascular conditions and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
Rho (United States)
2025
Lurie Children's Hospital
2021-2024
Northwestern University
2022-2023
Children's Hospital of Philadelphia
2018-2020
University of Pennsylvania
2020
Philadelphia University
2020
Chesterfield Royal Hospital
2017
University of Nebraska Medical Center
2016
Medical Research Council
2014
Borgess Medical Center
2011-2012
Background: Trauma centers are more frequently evaluating patients who receiving anticoagulant or prescription antiplatelet (ACAP) therapy at the time of injury. Because there reports delayed intracranial hemorrhage (ICH) after blunt trauma in this patient group, we evaluated ACAP with a head computed tomography (CT) on admission (CT1) followed by routine repeat CT (CT2) 6 hours. We hypothesized that among no traumatic findings CT1 and normal unchanged interval neurologic examination,...
Objectives: To assess focused cardiac ultrasound impact on clinician hemodynamic characterization of patients with suspected septic shock as well expert-generated algorithm performance. Design: Retrospective, observational study. Setting: Single-center, noncardiac PICU. Patients: Less than 18 years old receiving study within 72 hours sepsis pathway initiation from January 2014 to December 2016. Interventions: Hemodynamics were characterized fluid responsive, myocardial dysfunction,...
Autoimmune disease patients on immunosuppressants exhibit reduced humoral responses to primary COVID-19 vaccination. Booster vaccine and the effects of holding immunosuppression around vaccination are less studied. We evaluated efficacy safety additional in mycophenolate mofetil/mycophenolic acid (MMF/MPA)-, methotrexate (MTX)-, B cell-depleting therapy (BCDT)-treated autoimmune patients, including impact withholding MMF/MPA MTX. In this open-label, multicenter, randomized trial, 22...
Background and Purpose— Although atherosclerotic plaque in the carotid coronary arteries is accepted as a cause of ischemia, vertebral artery ostium (VAO) not widely recognized source ischemic stroke. We seek to demonstrate its implication some posterior circulation ischemia. Methods— This nonrandomized, prospective, single-center registry on consecutive patients presenting with ischemia who underwent VAO stenting for significant stenosis. Diagnostic evaluation imaging studies determined...
Despite increased recanalization rates in the treatment of acute ischemic stroke, percentage patients with a good clinical outcome all those treated has not risen above 50%. This 50% barrier may be broken by improving criteria for selection. study investigated addition capillary index score (CIS), new assessing remaining viable tissue area, to existing criteria.The Borgess Medical Center Ischemic Stroke Registry is non-randomized single-center single-operator registry consecutive subjects...
Background: Optimal care of trauma patients requires cost-effective organization and commitment center resources. We examined the impact creating a dedicated unit (TCU) adding advanced practice nurses on quality cost at an adult Level I center. Methods: Patient demographic injury data, length stay, complications, outcomes, total direct were evaluated for four 1-year intervals in recent history our center: Year A, team in-house surgeons resident physicians; B, addition nurse practitioners to...
<h3>BACKGROUND AND PURPOSE:</h3> Intracranial angioplasty and stent placement are used to treat intracranial atherosclerotic disease. The 2 interventions have not been directly compared. <h3>MATERIALS METHODS:</h3> This was a single-center, single-operator registry of consecutive, symptomatic subjects receiving treatment (angioplasty, BMS, or WS, chosen based on safety as judged by the operator). After November 2005, alone abandoned following introduction WS. primary end point stroke rate...
Objectives: Determine level of agreement among clinical signs shock type, identify which clinicians prioritize to determine type and select vasoactive medications, test the association type-vasoactive mismatch with prolonged organ dysfunction or death (complicated course). Design: Retrospective observational study. Setting: Single large academic PICU. Patients: Patients less than 18 years treated on a critical care sepsis pathway between 2012 2016. Interventions: None. Measurements Main...
<h3>BACKGROUND AND PURPOSE:</h3> The WASID study established the risk of subsequent ischemic stroke at 1 year in subjects with symptomatic intracranial atherosclerotic stenosis (70%–99%) 18%. efficacy different methods endovascular revascularization prevention still has not been established. We compared rate our registry following intervention results to identify which method, if any, provides most benefit prevention. This result from BMC-IRR follows a previously published article comparing...
Peripheral arterial catheters (PACs), and their associated complications, are common in the pediatric intensive care unit (PICU). Accidental catheter displacement non-functional PACs most this may be related to inadequate securement. There is mixed guidance on best way secure prevent complications. The authors hypothesized that sutures would not with a decreased risk of malfunction or accidental removal.
Impacted esophageal foreign bodies are a relatively common indication for urgent endoscopy [1]. We report case, and demonstrate with video, the endoscopic removal of perforating fish bone closure perforation.
Background and aims: Sepsis remains an important cause of death disability among children. Low-dose corticosteroid replacement therapy is used on PICU for children with severe septic shock, without evidence benefit or no harm. Aims: We aimed to explore potential endocrine immune-modulatory effects corticosteroids inform a phase 3 trial. Methods: Children shock were recruited from three UK PICUs. After ACTH test, patients randomised 2:1 standard care plus hydrocortisone (25 mg/m2/q 6 hourly...
OBJECTIVES/GOALS: Fluid boluses are administered to hypotensive, critically ill children but may not reverse hypotension, leading delay of vasoactive infusion, end-organ damage, and mortality. We hypothesize that a machine learning-based model will predict which have sustained response fluid bolus. METHODS/STUDY POPULATION: conduct single-center retrospective observational cohort study hypotensive who received intravenous isotonic at least 10 ml/kg within 72 hours pediatric intensive care...
Arnoldi, Sara; Glau, Christie; Walker, Sarah; Himebauch, Adam; Parikh, Darshana; Udeh, Simone; Weiss, Scott; Fitzgerald, Julie; Nishisaki, Akira; Conlon, Thomas Author Information
Introduction: Arterial catheters are a common form of monitoring in the pediatric intensive care unit (PICU) but complication is accidental line displacement. Although arterial lines frequently sutured to decrease risk displacement, it unknown whether this practice reduces inadvertent removal. We aimed determine association suturing as securement method with displacement due Methods: conducted single site retrospective cohort study placed by member PICU team from December 2019 April 2023....
Walker, Sarah1; Conlon, Thomas2; Zhang, Bingqing1; Mensinger, Janell3; Fitzgerald, Julie1; Himebauch, Adam4; Glau, Christie1; Nishisaki, Akira4; Ranjit, Suchitra5; Nadkarni, Vinay6; Weiss, Scott4 Author Information
Introduction: Fluid boluses are commonly administered to critically ill children with hypotension, but response is inconsistent. Inability predict bolus may delay vasoactive infusion, increasing time in shock and leading fluid overload. Stroke volume (SV) varies both contractility of via the Starling curve relationship. The maximum rate systolic upstroke arterial line waveform (dp/dtmax) a load-dependent estimate cardiac associated SV bolus. We hypothesized that as dp/dtmax has previously...
Walker, Sarah; Honegger, Kyle; Carroll, Michael; Weese-Mayer, Debra; Sanchez-Pinto, L. Nelson Author Information