Xiaoling Liao

ORCID: 0000-0003-4905-845X
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Research Areas
  • Bone Tissue Engineering Materials
  • Electrospun Nanofibers in Biomedical Applications
  • Cellular Mechanics and Interactions
  • Graphene and Nanomaterials Applications
  • Advanced Nanomaterials in Catalysis
  • Silk-based biomaterials and applications
  • 3D Printing in Biomedical Research
  • Nanocluster Synthesis and Applications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Nanoplatforms for cancer theranostics
  • Nanoparticle-Based Drug Delivery
  • Advanced biosensing and bioanalysis techniques
  • Cancer-related molecular mechanisms research
  • Cell Adhesion Molecules Research
  • Polymer Surface Interaction Studies
  • Carbon and Quantum Dots Applications
  • Fish Biology and Ecology Studies
  • Fish Ecology and Management Studies
  • Electrochemical sensors and biosensors
  • Algebraic structures and combinatorial models
  • Advanced Topics in Algebra
  • Advanced Sensor and Energy Harvesting Materials
  • Cerebrospinal fluid and hydrocephalus
  • Surface Modification and Superhydrophobicity
  • Dental Implant Techniques and Outcomes

Beijing Tian Tan Hospital
2024-2025

Capital Medical University
2023-2025

Guangxi Medical University
2024

Chongqing University of Science and Technology
2015-2024

Tianjin Stomatological Hospital
2024

National Clinical Research Center for Digestive Diseases
2024

First Affiliated Hospital of GuangXi Medical University
2024

The People's Hospital of Guangxi Zhuang Autonomous Region
2024

Southwest University
2022-2023

Capital University
2023

Atherosclerosis (AS), the underlying cause of most cardiovascular events, is one common causes human morbidity and mortality worldwide due to lack an efficient strategy for targeted therapy. In this work, we aimed develop ideal biomimetic nanoparticle AS Methods: Based on macrophage "homing" into atherosclerotic lesions cell membrane coating nanotechnology, nanoparticles (MM/RAPNPs) were fabricated with a (MM) surface rapamycin-loaded poly (lactic-co-glycolic acid) copolymer (PLGA) (RAPNPs)....

10.7150/thno.47841 article EN cc-by Theranostics 2020-10-09

Object. The purpose of this paper is to elucidate the safety and efficacy of, indications outcome prognosis for endoscopic third ventriculostomy (ETV) in 58 patients with obstructive hydrocephalus. Methods. Between September 1999 April 2003, ETVs were performed hydrocephalus (36 male 22 female patients) at authors' institution. ages ranged from 5 67 years (mean age 35 years) follow-up period 3 41 months duration follow up 24 months). Patients divided into four subgroups based on cause...

10.3171/jns.2004.100.4.0626 article EN Journal of neurosurgery 2004-04-01

Abstract The development of nanomedicines provides new opportunities for the treatment atherosclerosis (AS) due to their great advantages such as improved drug solubility, enhanced bioavailability and reduced side effects. Despite these advantages, are still facing some challenges. problems remain in short circulation life, lack specific targeting poor release controllability. In order overcome shortages conventional nanomedicines, combination biomimetic strategy with smart nanoagents has...

10.1093/rb/rbab033 article EN cc-by Regenerative Biomaterials 2021-06-21

While Src plays crucial roles in shear stress-induced cellular processes, little is known on the spatiotemporal pattern of high stress (HSS)-induced activation. HSS (65 dyn/cm(2)) was applied bovine aortic endothelial cells to visualize dynamic activation at subcellular levels utilizing a membrane-targeted biosensor (Kras-Src) based fluorescence resonance energy transfer (FRET). A polarized observed with higher activity side facing flow, which enhanced by cytochalasin D-mediated disruption...

10.1038/srep07008 article EN cc-by-nc-nd Scientific Reports 2014-11-12

Nanofibrous poly(l-lactic acid) (PLLA) membrane-simulated extracellular matrices (ECMs) can be used in the biomedical field. However, hydrophobic nature and poor osteoinductive property of PLLA limit its application guided bone regeneration (GBR). In this work, a methacrylated gelatin/nano-HA (GelMA/nHA) complex was first synthesized situ then introduced into to fabricate biomimetic GelMA/nHA/PLLA membranes, mimicking nanofibrous architecture composition ECMs by electrospinning...

10.1021/acsbiomaterials.0c00972 article EN ACS Biomaterials Science & Engineering 2020-11-09

Abstract Minimally invasive treatment via injectable delivery of cells has drawn extensive attention for tissue regeneration because it reduces the need substantial open surgery and fits defects with complex shapes, making a suitable option repairing articular cartilage defects. This work presents an alkaline method to fabricate open‐porous poly (lactic‐co‐glycolic acid) microspheres (OPMs) as bone marrow stromal (BMSCs) carriers regeneration. OPMs have better biodegradation property...

10.1002/jbm.a.37196 article EN Journal of Biomedical Materials Research Part A 2021-04-18

Silk fibroin (SF) from Bombyx mori is a natural polymer with exceptional biocompatibility, low immunogenicity, and ease of processability. SF-based hydrogels have been identified as one the most attractive candidate scaffolds for tissue engineering can be fabricated through various physical or chemical crosslinking approaches. However, conventional SF may suffer several major drawbacks, such structural inhomogeneity, poor mechanical properties utilization cytotoxic reagents. Herein, dually...

10.1080/09205063.2021.1932070 article EN Journal of Biomaterials Science Polymer Edition 2021-05-18

Cell membrane is the first medium from where a cell senses and responds to external stress stimuli. Exploring tension changes in will help us understand intracellular force transmission. Here, biosensor (named MSS) based on fluorescence resonance energy transfer developed visualize tension. Validity of verified for detection Results show shear stress-induced heterogeneous distribution with biosensor, which strengthened by disruption microfilaments or enhancement fluidity, but weakened...

10.1016/j.isci.2018.09.002 article EN cc-by-nc-nd iScience 2018-09-01

Abstract Polymer‐stabilized liquid crystal (PSLC) devices can realize fast switching between transparent and scattering state, have been widely applied as smart windows optical shutters. It has many advantages such high transmittance, haze value, response speed, low driving voltage. The electro‐optical of PSLC depends on the properties molecules influence polymer network motion molecules. In this paper, effect morphology performance is systematically studied. By adding mono‐acrylate monomer...

10.1002/macp.202000185 article EN Macromolecular Chemistry and Physics 2020-08-25
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