Lin Wen

ORCID: 0009-0009-4042-1006
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Effects and risks of endocrine disrupting chemicals
  • GABA and Rice Research
  • Allelopathy and phytotoxic interactions
  • Remote Sensing and Land Use
  • Plant Parasitism and Resistance
  • Rice Cultivation and Yield Improvement
  • Angiogenesis and VEGF in Cancer
  • Advanced Algorithms and Applications
  • Advanced Measurement and Detection Methods
  • Health, Environment, Cognitive Aging
  • Phytochemistry and Biological Activities
  • Nutritional Studies and Diet
  • Spam and Phishing Detection
  • Face and Expression Recognition
  • Air Quality and Health Impacts
  • Data Stream Mining Techniques
  • Pesticide Exposure and Toxicity
  • Heavy Metal Exposure and Toxicity
  • Per- and polyfluoroalkyl substances research
  • MicroRNA in disease regulation
  • Zebrafish Biomedical Research Applications
  • RNA and protein synthesis mechanisms
  • Weed Control and Herbicide Applications
  • Plant Physiology and Cultivation Studies
  • Traditional Chinese Medicine Studies

Dalian Medical University
2023-2024

Chongqing University
2017-2023

Jinan University
2021-2023

Southeast University
2021-2023

Guangdong Medical College
2020

Qingdao Mental Health Center
2018-2019

Harbin Medical University
2017-2019

Fujian Agriculture and Forestry University
2013

South China Agricultural University
2012

Sichuan University
2010-2011

Excess activation of cardiac fibroblasts inevitably induces fibrosis. Emodin has been used as a natural medicine against several chronic diseases. The objective this study is to determine the effects emodin on fibrosis and underlying molecular mechanisms. Intragastric administration markedly decreased left ventricular wall thickness in mouse model pathological hypertrophy with excess induced by transaortic constriction (TAC) suppressed angiotensin II (AngII). upregulated expression...

10.1016/j.apsb.2019.04.003 article EN cc-by-nc-nd Acta Pharmaceutica Sinica B 2019-04-22

Abstract Background Bisphenol F (BPF) and bisphenol S (BPS) have replaced A (BPA) in the manufacturing of products containing polycarbonates epoxy resins; however, effects these substitutes on risk cardiovascular disease (CVD), including congestive heart failure, coronary disease, angina pectoris, attack, stroke, not been assessed. Objective To examine association urinary BPS BPF with CVD a U.S. representative population. Methods Cross-sectional data from 1267 participants aged 20–80 years...

10.1186/s12302-021-00586-9 article EN cc-by Environmental Sciences Europe 2022-01-10

The transport and metabolism of lipids in cerebrovascular endothelial cells (ECs) have been hypothesized to regulate blood-brain barrier (BBB) maturation homeostasis. Long-chain polyunsaturated fatty acids (LCPUFAs) as the important components cell membranes are essential for development function BBB, but direct links lipid ECs remain be established. Here, we comprehensively characterize transcriptomic phenotype developmental single-cell resolution firstly find that trans-2-enoyl-CoA...

10.34133/2022/9839368 article EN cc-by Research 2022-01-01

Background: Acrylamide is a well-known potential carcinogenic compound formed as an intermediate in the Maillard reaction during heat treatment, mainly from high-temperature frying, and found baked goods coffee, well resulting water textiles paper processing. The effects of acrylamide on lung disease humans remains unclear. We aimed to investigate association between blood glycidamide chronic obstructive pulmonary (COPD) United States America (U.S.) population using PROC logistic regression...

10.1039/d1fo02612g article EN Food & Function 2021-01-01

Clear-cell renal cell carcinoma (ccRCC) is an aggressive and malignant kidney cancer which has the worst prognosis. Although microRNAs (miRNAs) have recently been identified as a novel class of regulators in oncogenesis metastasis, there are few studies on their participation ccRCC. In present study, we observed that miR-367 expression was increased both human ccRCC tissues lines. Cell proliferation evaluated by MTT assay 5-Ethynyl-2'-deoxyuridine (EdU) kit, indicated inhibition could...

10.18632/oncotarget.18647 article EN Oncotarget 2017-06-27

There is little research on the relationship between phthalates exposure and sleep problems in adult females, with existing studies only assessing association to individual problems. We aimed analyse 1366 US females aged 20 years older from 2011-2014 National Health Nutrition Examination Survey (NHANES) by age stratification. Multivariate logistic regression showed that fourth quartile of MECPP increased risk 20–39 compared reference (OR: 1.87, 95% CI: 1.14, 3.08). The WQS index was...

10.1080/09603123.2023.2196056 article EN International Journal of Environmental Health Research 2023-03-27

Dark green islands (DGIs) are a common symptom of plants systemically infected with the mosaic virus. DGIs clusters leaf cells that free virus but surrounded by yellow tissue is full particles. In Cucumber (CMV)-infected Nicotiana tabacum leaves, respiration and photosynthesis capabilities tissues were measured. The results showed cyanide-resistant was enhanced in declined, while they less affected. activities oxygen-scavenging enzymes catalase (CAT), peroxidase (POD), superoxide dismutase...

10.1515/znc-2010-1-213 article EN cc-by-nc-nd Zeitschrift für Naturforschung C 2010-02-01

Wnt/β-catenin is a signaling pathway associated with embryonic development, organ formation, cancer, and fibrosis. Its activation can repair kidney damage during acute injury (AKI) accelerate the occurrence of renal fibrosis after chronic disease (CKD). Interestingly, p53 has also been found as key modulator in AKI CKD recent years. Meantime, some studies have crosstalk between pathways p53, but more evidence required on whether they synergistic effects progression. This article reviews role...

10.23876/j.krcp.23.344 article EN cc-by-nc-nd Kidney Research and Clinical Practice 2024-11-18

Alzheimer's Disease (AD) is a chronic progressive neurodegenerative disorder in central nervous system seen.We aimed to study the miR-107 pathology through regulating SYK and NF-κB signaling pathway.Bioinformatics analysis was performed screen pathway differentially expressed genes. The target relationship between verified by dual luciferase assay. QRT-PCR western blot were used verify expression level of miR-107, NF- κB related proteins hippocampus primary neurons. BAY61-3606 BAY11-7082...

10.2174/1567205016666181212154347 article EN Current Alzheimer Research 2018-12-13

Recent studies have focused on capillary pruning in various organs and species. However, the way which large-diameter vessels are pruned remains unclear. Here we show that of zebrafish caudal vein (CV) from ventral capillaries CV plexus different transgenic embryos is driven by endothelial cell (EC) rearrangement, involves EC nucleus migration, junction remodeling, actin cytoskeleton remodeling. Further observation reveals a growing difference blood flow velocity between two embryos. With...

10.1371/journal.pgen.1009690 article EN cc-by PLoS Genetics 2021-07-28
Coming Soon ...