A5101450364- Migraine and Headache Studies
- Trigeminal Neuralgia and Treatments
- Sympathectomy and Hyperhidrosis Treatments
- Ophthalmology and Eye Disorders
- Cardiovascular Syncope and Autonomic Disorders
- Cerebral Venous Sinus Thrombosis
- Botulinum Toxin and Related Neurological Disorders
- Neurological disorders and treatments
- Olfactory and Sensory Function Studies
- Restraint-Related Deaths
- Neurosurgical Procedures and Complications
- Neuroscience of respiration and sleep
- Pituitary Gland Disorders and Treatments
- Blood disorders and treatments
- Health, Medicine and Society
- Vascular Malformations Diagnosis and Treatment
- Peripheral Neuropathies and Disorders
- Cerebrospinal fluid and hydrocephalus
- Body Image and Dysmorphia Studies
- Oropharyngeal Anatomy and Pathologies
- S100 Proteins and Annexins
- Acute Ischemic Stroke Management
- Alzheimer's disease research and treatments
- SARS-CoV-2 and COVID-19 Research
- Stress and Burnout Research
Hospital Clínico Universitario de Valencia
2010-2024
Universitat de València
2008-2024
Sociedad Española de Nefrología
2024
INCLIVA Health Research Institute
2024
Plains Health Centre
2000
Epsom Hospital
2000
Hospital General Universitario de Alicante Doctor Balmis
2000
Karolinska University Hospital
2000
Hospital General Universitario De Valencia
1999
Headache disorders are very common, but their monetary costs in Europe unknown. We performed the first comprehensive estimation of how economic resources lost to headache Europe. From November 2008 August 2009, a cross-sectional survey was conducted eight countries representing 55% adult EU population. Participation rates varied between 11% and 59%. In total, 8412 questionnaires contributed this analysis. Using bottom-up methodology, we estimated direct (medications, outpatient health care,...
European data, at least from Western Europe, are relatively good on migraine prevalence but less sound for tension-type headache (TTH) and medication-overuse (MOH). Evidence impact of disorders is very limited. Eurolight was a data-gathering exercise primarily to inform health policy in the Union (EU). This manuscript reports personal impact. The study cross-sectional with modified cluster sampling. Surveys were conducted by structured questionnaire, including diagnostic questions based...
Headache disorders and psychiatric are both common, while evidence, mostly pertaining to migraine, suggests they comorbid more often than might be expected by chance. There good reasons for establishing whether are: symptoms of illnesses may summate synergistically; comorbidities hinder management, negatively influencing outcomes; high-level comorbidity indicates that, where one disease occurs, the other should looked for. The Eurolight project gathered population-based data on these from...
Objectives The sphenopalatine ganglion (SPG) plays a pivotal role in cluster headache (CH) pathophysiology as the major efferent parasympathetic relay. We evaluated long-term effectiveness of SPG stimulation medically refractory, chronic CH patients. Methods Thirty-three patients were enrolled an open-label follow-up study original Pathway CH-1 study, and participated through 24 months post-insertion microstimulator. Response to therapy was defined acute ≥ 50% attacks or reduction attack...
Most primary headaches are episodic, and most estimates of the heavy disability burden attributed to headache derive from epidemiological data focused on episodic subtypes migraine tension-type (TTH). These disorders give rise directly but intermittently symptom burden. Nevertheless, people with these may not be symptom-free between attacks. We analysed Eurolight dataset for interictal was a cross-sectional survey using modified cluster sampling adult population (18–65 years) in 10 countries...
Cluster headache (CH) is a debilitating disorder with severe consequences for patient quality of life. On-demand neuromodulation targeting the sphenopalatine ganglion (SPG) effective in treating acute pain and subgroup patients experience decreased frequency CH attacks. We monitored self-reported attack frequency, disability, medication intake 33 medically refractory, chronic (CCH) an open label follow-up study original Pathway CH-1 study. Patients were followed at least 24 months (average...
The Eurolight project is the first at European Union level to assess impact of headache disorders, and also its scale performed by collaboration between professional lay organizations individuals. Here are reported methods developed for it. took form surveys, structured questionnaire, conducted in ten countries Europe which together represented 60% adult population Union. In Lithuania, survey was population-based. Elsewhere, truly population-based studies were impractical reasons cost,...
Introduction. Since the beginning of COVID-19 epidemic caused by SARS-CoV-2 virus, olfactory alterations have been observed at a greater frequency than in other coronavirus epidemics. While may be patients with rhinovirus, influenza or parainfluenza virus infection, they are typically explained nasal obstruction mucus direct epithelial damage; case SARS-CoV-2, present without congestion mucus. We performed study presenting olfactory/gustatory context infection order to contribute...
Conclusion: The calcineurin inhibitor tacrolimus (TCR) and the pineal gland hormone antioxidant melatonin (MLT) have been shown to possess otoprotective properties against noise-induced hearing loss (NIHL). In contrast, dexamethasone (DXM) was not effective as an agent NIHL. Further studies are needed understand exact molecular mechanisms involved. Objective: Exposure noise pollution use of audio devices for long periods time at high volume is known cause or Our goal evaluate effectiveness...
We developed a 103-item self-reporting questionnaire to assess the burden of primary headache disorders on those affected by them, including characteristics, associated disability, co-morbidities, disease-management and quality life. validated in five languages with 426 participants (131 UK, 60 Italy, 107 Spain, 83 Germany/Austria, 45 France). After linguistic face-content validation, we tested for comprehensibility, internal consistency test–retest reliability at an interval one month. In...
To analyze the trajectory to diagnosis and information provided in a series of cluster headache (CH) patients from five clinics.CH were asked fill an ad hoc questionnaire.Seventy-five (mean age 41.5 years, 67 males) completed questionnaire. Patients had visited during average 4.9 years mean 4.6 physicians who obtained 2.5 neuroimaging procedures per patient before getting CH. Sixty-three (84%) received no (21 cases; 28%), while 43 (57%) been given 2.1 alternative diagnoses. Migraine,...
Abstract Background Surveys enquiring about burden of headache over a prior period time ( eg , 3 months) are subject to recall bias. To eliminate this as far possible, we focused on presence and impact the preceding day (“headache yesterday”). Methods Adults (18-65 years) were surveyed from general populations Germany, Italy, Lithuania, Luxembourg Netherlands, work-force population in Spain mostly non-headache patient Austria, France UK. A study non-responders some countries allowed...
This randomized, double-blind, double-dummy, multicenter, parallel-group study aimed at comparing the efficacy and safety of calcium carbasalate (equivalent to 900 mg aspirin) plus metoclopramide 10 (CM) with ergotamine tartrate 1 caffeine 100 (EC) administered in treatment 2 acute migraine attacks. A total 296 patients fulfilling International Headache Society diagnostic criteria for were enrolled. In total, one or two attacks treated 268 235 patients, respectively. The primary endpoint...