A5075197560- Genetics, Aging, and Longevity in Model Organisms
- Animal Behavior and Reproduction
- Insect and Arachnid Ecology and Behavior
- Circadian rhythm and melatonin
- Dietary Effects on Health
- Software Engineering Research
- Insect Utilization and Effects
- Scientific Computing and Data Management
- Reproductive biology and impacts on aquatic species
- Obesity and Health Practices
- Species Distribution and Climate Change
- Physiological and biochemical adaptations
- Genomics and Phylogenetic Studies
- Plant and animal studies
- Meta-analysis and systematic reviews
- Insect and Pesticide Research
- Forest Insect Ecology and Management
- Insect Pest Control Strategies
- Fish Ecology and Management Studies
- Data Analysis with R
- Insect-Plant Interactions and Control
- Spaceflight effects on biology
- Research Data Management Practices
- Technology Assessment and Management
- Climate Change and Health Impacts
University of Glasgow
2022-2025
University of East Anglia
2019-2023
Google (United States)
2023
University of Edinburgh
2018-2022
Norwich Research Park
2019-2021
Institut de Biologia Evolutiva
2018
Contributor Roles Taxonomy (CRediT) has recently changed how author contributions are acknowledged. To extend and complement CRediT, we propose MeRIT, a new way of writing the Methods section using author's initials to further clarify contributor roles for reproducibility replicability. Lack information on authors' contribution specific aspects study hampers Here, authors new, easily implemented reporting system in an article.
High quality research data and analytical code are essential for ensuring the credibility of scientific results, key outputs, crucial elements to facilitate reproducibility. However, in ecology evolution (E&E) particular, it is currently unknown how many journals have policies on data- code-sharing peer review purposes, or upon manuscript acceptance. Furthermore, clarity such may impact authors' compliance. Thus, we assessed clarity, strictness, timing across 275 E&E. We also...
Code review increases reliability and improves reproducibility of research. As such, code is an inevitable step in software development common fields such as computer science. However, despite its importance, noticeably lacking ecology evolutionary biology. This problematic it facilitates the propagation coding errors a reduction published results. To address this, we provide detailed commentary on how to effectively code, set up your project enable this form detail possible implementation...
Maternal senescence is the detrimental effect of increased maternal age on offspring performance. Despite much recent interest given to describing this phenomenon, its distribution across animal species poorly understood. A review published literature finds that affects pre-adult survival in 252 272 populations (93%) representing 97 species. Age effects tended be deleterious invertebrates and mammals, including humans, confirming presence senescence. However, bird were a conspicuous...
Publishing preprints is quickly becoming commonplace in ecology and evolutionary biology. Preprints can facilitate the rapid sharing of scientific knowledge establishing precedence enabling feedback from research community before peer review. Yet, significant barriers to preprint use exist, including language barriers, a lack understanding about benefits diversity types outputs accepted (e.g. reports). Community-driven initiatives allow come together break down these improve equity coverage...
Heatwaves, temporary periods of elevated temperatures, are increasing both in magnitude and frequency have been shown to devastating negative effects on a wide range taxa. However, date, most studies investigating the impacts heatwaves either focus populations that evolved under constant conditions prior assaying or, more importantly, only investigated short-term outcomes temperatures. Here, using seed beetle, Callosobruchus maculatus, we investigate short- long-term evolution after 43...
Abstract The theory that ageing evolves because of competitive resource allocation between the soma and germline has been challenged by studies showing somatic maintenance can be improved without impairing reproduction. However, it suggested cost-free improvement in is possible only under a narrow range benign conditions. Here, we show experimental downregulation insulin/IGF-1 signaling (IIS) C. elegans nematodes, robustly reproducible life span- health span-extending treatment, reduces...
Dietary restriction (DR) increases lifespan in a broad variety of organisms and improves health humans. However, long-term transgenerational consequences dietary interventions are poorly understood. Here, we investigated the effect DR by temporary fasting (TF) on mortality risk, age-specific reproduction fitness across three generations descendants Caenorhabditis elegans . We show that while TF robustly reduces risk late-life individuals subject to (P 0 ), it has wide range both positive...
Dietary restriction (DR) improves survival across a wide range of taxa yet remains poorly understood. The key unresolved question is whether this evolutionarily conserved response to temporary lack food adaptive. Recent work suggests that early-life DR reduces and reproduction when nutrients subsequently become plentiful, thereby challenging adaptive explanations. A new hypothesis maintains increased under results from reduced costs overfeeding. We tested the value in an outbred population...
Ageing evolves because the force of selection on traits declines with age but proximate causes ageing are incompletely understood. The ‘disposable soma’ theory (DST) upholds that competitive resource allocation between reproduction and somatic maintenance underpins evolution lifespan. In contrast, developmental (DTA) suggests organismal senescence is caused by suboptimal gene expression in adulthood. While DST predicts trade-off lifespan, DTA age-specific optimization can increase lifespan...
Abstract In some species, permanent curtailment of reproduction part‐way through the lifespan adult females is a feature their evolved life history. The existence such post‐reproductive stage apparently rare; reasonably robust evidence for this confined to only six species (humans, Asian elephants and four whales). That it occurs at all appears contradict our view natural selection operating maximize fitness special circumstances must exist explain its occurrence. We evaluate main hypotheses...
Maternal effect senescence has attracted much recent scientific interest. However, the age-related effects of pre- and postnatal maternal age are often conflated, as these naturally originate from same individual. Additionally, many studies fail to account for potential biases associated with selective disappearance. Here we use a cross-fostered laboratory population burying beetle, Nicrophorus vespilloides, examine both female on offspring life-history traits postcare outcomes mothers while...
Code review increases reliability and improves reproducibility of research. As such, code is an inevitable step in software development common subjects such as computer science. However, despite its importance, noticeably lacking ecology evolutionary biology. This problematic it facilitates the propagation coding errors a reduction published results. To address this, we provide detailed commentary on how to effectively code, set up your project enable this form detail possible implementation...
Parental age at reproduction influences offspring size and survival by affecting prenatal postnatal conditions in a wide variety of species, including humans. However, most investigations into this manifestation ageing focus upon maternal effects; the effects paternal interactions between are often neglected. Furthermore, even when studied, pre- post-natal confounded. Using cross-fostered experimental design, we investigated joint pre-natal ages on five traits related to outcomes laboratory...
Fasting increases lifespan in invertebrates, improves biomarkers of health vertebrates and is increasingly proposed as a promising route to improve human health. Nevertheless, little known about how fasted animals use resources upon refeeding, such decisions affect putative trade-offs between somatic growth repair, reproduction gamete quality. Such fasting-induced are based on strong theoretical foundations have been recently discovered but the data lacking. Here, we report that female zebrafish,
Abstract Dietary restriction increases lifespan in a broad variety of organisms and improves health humans. However, long-term transgenerational consequences dietary interventions are poorly understood. Here we investigated the effect by temporary fasting (TF) on mortality risk, age-specific reproduction fitness across three generations descendants C. elegans . We show that while TF robustly reduces risk late-life parental generation (P 0 ), it has wide range both positive deleterious...
Human-induced environmental change can influence populations both at the global level through climatic warming and local habitat fragmentation. As become more isolated, they suffer from high levels of inbreeding, which contributes to a reduction in fitness, termed inbreeding depression. However, it is still unclear if this increase homozygosity also results corresponding sensitivity stressful conditions, could intensify already detrimental effects warming. Here, fully factorial design, we...
Abstract Climate change is associated with the increase in both mean and variability of thermal conditions. Therefore, use more realistic fluctuating regimes most appropriate laboratory method for predicting population responses to heterogeneity. However, long- short-term implications evolving under such conditions are not well understood. Here, we examined differences key life-history traits among populations seed beetles (Callosobruchus maculatus) that evolved either constant control or an...
Abstract Maternal senescence is a reduction in individual performance associated with an increase its mother’s age at conception. When manifested on adult lifespan, this known as the ‘Lansing Effect’. Single-species studies report both maternal age-related increases and decreases but no comprehensive review of literature has yet determined if Lansing Effect widespread phenomenon. To address knowledge gap, we performed meta-analysis aging rates taken from all available published studies. We...
Abstract Fasting increases lifespan in invertebrates, improves biomarkers of health vertebrates, and is increasingly proposed as a promising route to improve human health. Nevertheless, little known about how fasted animals use resources upon refeeding, such decisions affect putative trade-offs between somatic growth repair, reproduction, gamete quality. Such fasting-induced are based on strong theoretical foundations have been recently discovered but the data vertebrates lacking. Here we...