Franziska Werner

ORCID: 0000-0003-4912-1615
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About
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Research Areas
  • Characterization and Applications of Magnetic Nanoparticles
  • Geomagnetism and Paleomagnetism Studies
  • Microfluidic and Bio-sensing Technologies
  • Minerals Flotation and Separation Techniques
  • Parallel Computing and Optimization Techniques
  • Modular Robots and Swarm Intelligence
  • Mental Health Research Topics
  • Embedded Systems Design Techniques
  • Functional Brain Connectivity Studies
  • Magnetic properties of thin films
  • Advanced MRI Techniques and Applications
  • Distributed and Parallel Computing Systems
  • Electrical and Bioimpedance Tomography
  • Sperm and Testicular Function
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Computational Physics and Python Applications
  • Advanced Data Storage Technologies
  • Magnetic and Electromagnetic Effects
  • Behavioral Health and Interventions
  • Veterinary Medicine and Surgery
  • Cardiovascular Health and Disease Prevention

University Medical Center Hamburg-Eppendorf
2015-2023

Universität Hamburg
1975-2023

Hamburg University of Technology
2015-2023

Abstract Determining the brain perfusion is an important task for diagnosis of vascular diseases such as occlusions and intracerebral haemorrhage. Even after successful diagnosis, there a high risk restenosis or rebleeding that patients need intense attention in days treatment. Within this work, we present diagnostic tomographic imager allows access to quantitatively short intervals. The device based on magnetic particle imaging technology designed human scale. It highly sensitive detection...

10.1038/s41467-019-09704-x article EN cc-by Nature Communications 2019-04-26

Purpose In-vitro evaluation of the feasibility 4D real time tracking endovascular devices and stenosis treatment with a magnetic particle imaging (MPI) / resonance (MRI) road map approach an MPI-guided using blood pool tracer. Materials Methods A guide wire angioplasty-catheter were labeled thin layer lacquer. For MPI custom made software framework was developed. stenotic vessel phantom filled saline or superparamagnetic iron oxide nanoparticles (MM4) equipped bimodal fiducial markers for...

10.1371/journal.pone.0156899 article EN cc-by PLoS ONE 2016-06-01

Biomedical applications such as cell tracking and angiography require the detection of low concentrations superparamagnetic iron oxide nanoparticles (SPIOs) for imaging purposes. Magnetic particle (MPI) is a new technology which enables quantitative time-resolved localization SPIO distributions. However, minimum concentration at SPIOs can be reconstructed with suitable quality still remains to investigated. In this work we examine background signals in raw data that were measured without any...

10.1109/tmi.2015.2501462 article EN IEEE Transactions on Medical Imaging 2015-11-20

The purpose of this work was to demonstrate the capability magnetic particle imaging (MPI) assess hemodynamics in a realistic 3D aneurysm model obtained by additive manufacturing. MPI compared with resonance (MRI) and dynamic digital subtraction angiography (DSA).The saccular morphology (7 mm dome height, 5 cross-section, 3-4 neck, 3.5 parent artery diameter) connected peristaltic pump delivering physiological flow (250 mL/min) pulsation rate (70/min). High-resolution (4 h long) 4D phase...

10.1371/journal.pone.0160097 article EN cc-by PLoS ONE 2016-08-05

Magnetic particle imaging is a tracer-based method that utilizes the non-linear magnetization response of iron-oxide for determining their spatial distribution. The based on sampling scheme where sensitive spot moved along trajectory captured predefined field-of-view (FOV). However, particles outside FOV also contribute to measurement signal due rotation and non-sharpness spot. In present work we investigate artifacts are induced by not covered show can be mitigated using system matrix...

10.1088/0031-9155/61/2/475 article EN Physics in Medicine and Biology 2015-12-18

Magnetic particle imaging (MPI) is a tomographic technique for determining the spatial distribution of superparamagnetic nanoparticles. Current MPI systems are capable iron masses over wide dynamic range more than four orders magnitude. In theory, this could be further increased using adaptive amplifiers, which prevent signal clipping. While applies to single sample, severely limited if several samples with different concentrations or strongly inhomogeneous distributions considered. One...

10.1088/1361-6560/abf202 article EN Physics in Medicine and Biology 2021-03-25

Magnetic particle imaging (MPI) is a quantitative modality that allows us to determine the distribution of superparamagnetic nanoparticles. Sampling achieved by moving field-free point (FFP) along specific trajectory through volume interest. The magnetic material lies path or in close vicinity FFP changes its magnetization and induces voltage surrounding receiver coils. Various trajectories for are conceivable, but most experimental MPI scanners either use Cartesian Lissajous sampling...

10.1088/1361-6560/aa6177 article EN Physics in Medicine and Biology 2017-02-20

Magnetic particle imaging (MPI) is a quantitative modality that allows the distribution of superparamagnetic nanoparticles to be visualized. Compared other techniques like x-ray radiography, computed tomography (CT), and magnetic resonance (MRI), MPI only provides signal from administered tracer, but no additional morphological information, which complicates geometry planning interpretation MP images. The purpose authors' study was develop bimodal fiducial markers can visualized by MRI in...

10.1118/1.4948998 article EN Medical Physics 2016-05-16

The Spielberger State Trait Anxiety Inventory (STAI) is the most cited measure of general trait negative affect and employed in a wide variety research contexts. Although STAI scale (STAI-T) assumed to assess trait-like characteristic, little known about its long-term temporal stability. Here, we investigate stability German version STAI-T across multiple measurement time points spanning 5 months 3.5 years two independent samples (105 female Caucasians 120 mixed sex Caucasians). We replicate...

10.31234/osf.io/mubgv preprint EN 2022-05-06

Magnetic Particle Imaging (MPI) determines the distribution of superparamagnetic nanoparticles. Signal encoding is achieved by moving a field-free point (FFP) through volume interest. Due to its simplicity Cartesian trajectory used in many experimental scanner setups. One drawback that spatial resolution anisotropic and particular lower orthogonal excitation direction. In order get fully isotropic one can extend unidirectional bidirectional switches direction after first pass over When...

10.18416/ijmpi.2017.1703007 article EN International journal on magnetic particle imaging 2017-03-22
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